Zobrazeno 1 - 10 of 1 422 pro vyhledávání: '"Loenarz C"'
1
Akademický článek
Non-canonical nucleosides: Biomimetic triphosphorylation, incorporation into mRNA and effects on translation and structure.
Autor: Benčić P; Institute of Pharmaceutical Sciences, University of Freiburg, Germany., Keppler M; Institute of Pharmaceutical Sciences, University of Freiburg, Germany., Kuge M; Institute of Pharmaceutical Sciences, University of Freiburg, Germany., Qiu D; Institute of Organic Chemistry, University of Freiburg, Germany., Schütte LM; Institute of Pharmaceutical Sciences, University of Freiburg, Germany., Häner M; Institute of Organic Chemistry, University of Freiburg, Germany., Strack K; Institute of Pharmaceutical Sciences, University of Freiburg, Germany., Jessen HJ; Institute of Organic Chemistry, University of Freiburg, Germany., Andexer JN; Institute of Pharmaceutical Sciences, University of Freiburg, Germany., Loenarz C; Institute of Pharmaceutical Sciences, University of Freiburg, Germany.
Publikováno v: The FEBS journal [FEBS J] 2023 Oct; Vol. 290 (20), pp. 4899-4920. Date of Electronic Publication: 2023 Jun 26.
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2
Akademický článek
β-lapachone regulates mammalian inositol pyrophosphate levels in an NQO1- and oxygen-dependent manner.
Autor: Eisenbeis VB; Faculty of Chemistry and Pharmacy, Institute of Organic Chemistry, Albert-Ludwigs-Universität Freiburg, Freiburg im Breisgau 79104, Germany., Qiu D; Faculty of Chemistry and Pharmacy, Institute of Organic Chemistry, Albert-Ludwigs-Universität Freiburg, Freiburg im Breisgau 79104, Germany.; The Center for Integrative Biological Signaling Studies, Albert-Ludwigs-Universität Freiburg, Freiburg im Breisgau 79104, Germany., Gorka O; Institute of Neuropathology, Faculty of Medicine, Medical Center, University of Freiburg, Freiburg 79106, Germany., Strotmann L; Faculty of Chemistry and Pharmacy, Institute of Organic Chemistry, Albert-Ludwigs-Universität Freiburg, Freiburg im Breisgau 79104, Germany., Liu G; Faculty of Chemistry and Pharmacy, Institute of Organic Chemistry, Albert-Ludwigs-Universität Freiburg, Freiburg im Breisgau 79104, Germany.; The Center for Integrative Biological Signaling Studies, Albert-Ludwigs-Universität Freiburg, Freiburg im Breisgau 79104, Germany., Prucker I; Faculty of Chemistry and Pharmacy, Institute of Organic Chemistry, Albert-Ludwigs-Universität Freiburg, Freiburg im Breisgau 79104, Germany., Su XB; Medical Research Council, Laboratory for Molecular Cell Biology, University College London, WC1E 6BT London, United Kingdom., Wilson MSC; Medical Research Council, Laboratory for Molecular Cell Biology, University College London, WC1E 6BT London, United Kingdom., Ritter K; Faculty of Chemistry and Pharmacy, Institute of Organic Chemistry, Albert-Ludwigs-Universität Freiburg, Freiburg im Breisgau 79104, Germany., Loenarz C; Faculty of Chemistry and Pharmacy, Institute for Pharmaceutical Sciences, Pharmaceutical and Medicinal Chemistry, Albert-Ludwigs-Universität Freiburg, Freiburg im Breisgau 79104, Germany., Groß O; The Center for Integrative Biological Signaling Studies, Albert-Ludwigs-Universität Freiburg, Freiburg im Breisgau 79104, Germany.; Institute of Neuropathology, Faculty of Medicine, Medical Center, University of Freiburg, Freiburg 79106, Germany., Saiardi A; Medical Research Council, Laboratory for Molecular Cell Biology, University College London, WC1E 6BT London, United Kingdom., Jessen HJ; Faculty of Chemistry and Pharmacy, Institute of Organic Chemistry, Albert-Ludwigs-Universität Freiburg, Freiburg im Breisgau 79104, Germany.; The Center for Integrative Biological Signaling Studies, Albert-Ludwigs-Universität Freiburg, Freiburg im Breisgau 79104, Germany.
Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2023 Aug 22; Vol. 120 (34), pp. e2306868120. Date of Electronic Publication: 2023 Aug 14.
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3
Akademický článek
Biomimetic S-Adenosylmethionine Regeneration Starting from Multiple Byproducts Enables Biocatalytic Alkylation with Radical SAM Enzymes.
Autor: Gericke L; Institute of Pharmaceutical Sciences, Pharmaceutical and Medicinal Chemistry, University of Freiburg, Albertstr. 25, 79104, Freiburg, Germany., Mhaindarkar D; Institute of Pharmaceutical Sciences, Pharmaceutical and Medicinal Chemistry, University of Freiburg, Albertstr. 25, 79104, Freiburg, Germany., Karst LC; Institute of Pharmaceutical Sciences, Pharmaceutical and Medicinal Chemistry, University of Freiburg, Albertstr. 25, 79104, Freiburg, Germany., Jahn S; Institute of Pharmaceutical Sciences, Pharmaceutical and Medicinal Chemistry, University of Freiburg, Albertstr. 25, 79104, Freiburg, Germany., Kuge M; Institute of Pharmaceutical Sciences, Pharmaceutical and Medicinal Chemistry, University of Freiburg, Albertstr. 25, 79104, Freiburg, Germany., Mohr MKF; Institute of Pharmaceutical Sciences, Pharmaceutical and Medicinal Chemistry, University of Freiburg, Albertstr. 25, 79104, Freiburg, Germany., Gagsteiger J; Institute of Pharmaceutical Sciences, Pharmaceutical Biology, University of Freiburg, Stefan-Meier-Str. 19, 79104, Freiburg, Germany., Cornelissen NV; Institute of Biochemistry, University of Münster, Corrensstr. 36, 48149, Münster, Germany., Wen X; Department of Chemistry, University of Basel, Mattenstr. 22, 4058, Basel, Switzerland., Mordhorst S; Institute of Pharmaceutical Sciences, Pharmaceutical and Medicinal Chemistry, University of Freiburg, Albertstr. 25, 79104, Freiburg, Germany.; Present address: Pharmaceutical Institute, Pharmaceutical Biology, University of Tübingen, Auf der Morgenstelle 8, 72076, Tübingen, Germany., Jessen HJ; Institute of Organic Chemistry, University of Freiburg, Albertstr. 21, 79104, Freiburg, Germany., Rentmeister A; Institute of Biochemistry, University of Münster, Corrensstr. 36, 48149, Münster, Germany., Seebeck FP; Department of Chemistry, University of Basel, Mattenstr. 22, 4058, Basel, Switzerland., Layer G; Institute of Pharmaceutical Sciences, Pharmaceutical Biology, University of Freiburg, Stefan-Meier-Str. 19, 79104, Freiburg, Germany., Loenarz C; Institute of Pharmaceutical Sciences, Pharmaceutical and Medicinal Chemistry, University of Freiburg, Albertstr. 25, 79104, Freiburg, Germany., Andexer JN; Institute of Pharmaceutical Sciences, Pharmaceutical and Medicinal Chemistry, University of Freiburg, Albertstr. 25, 79104, Freiburg, Germany.
Publikováno v: Chembiochem : a European journal of chemical biology [Chembiochem] 2023 May 02; Vol. 24 (9), pp. e202300133. Date of Electronic Publication: 2023 Apr 04.
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4
Born to sense: biophysical analyses of the oxygen sensing prolyl hydroxylase from the simplest animal Trichoplax adhaerens
Autor: Lippl, K, Boleininger, A, McDonough, M, Abboud, M, Tarhonskaya, H, Chowdhury, R, Loenarz, C, Schofield, C
Publikováno v: Hypoxia, Vol Volume 6, Pp 57-71 (2018)
Hypoxia
Kerstin Lippl, Anna Boleininger, Michael A McDonough, Martine I Abboud, Hanna Tarhonskaya, Rasheduzzaman Chowdhury, Christoph Loenarz, Christopher J Schofield Chemistry Research Laboratory, University of Oxford, Oxford, UK Background: In humans and o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::12df0e50165f2978b896ee7717d9e019
https://www.dovepress.com/born-to-sense-biophysical-analyses-of-the-oxygen-sensing-prolyl-hydrox-peer-reviewed-article-HP
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5
Akademický článek
A Cobalamin-Dependent Radical SAM Enzyme Catalyzes the Unique C α -Methylation of Glutamine in Methyl-Coenzyme M Reductase.
Autor: Gagsteiger J; Institut für Pharmazeutische Wissenschaften, Pharmazeutische Biologie, Albert-Ludwigs-Universität Freiburg, Stefan-Meier-Str. 19, 79104, Freiburg, Germany., Jahn S; Institut für Pharmazeutische Wissenschaften, Pharmazeutische und Medizinische Chemie, Albert-Ludwigs-Universität Freiburg, Albertstr. 25, 79104, Freiburg, Germany., Heidinger L; Institut für Biochemie, Albert-Ludwigs-Universität Freiburg, Albertstr. 21, 79104, Freiburg, Germany., Gericke L; Institut für Pharmazeutische Wissenschaften, Pharmazeutische und Medizinische Chemie, Albert-Ludwigs-Universität Freiburg, Albertstr. 25, 79104, Freiburg, Germany., Andexer JN; Institut für Pharmazeutische Wissenschaften, Pharmazeutische und Medizinische Chemie, Albert-Ludwigs-Universität Freiburg, Albertstr. 25, 79104, Freiburg, Germany., Friedrich T; Institut für Biochemie, Albert-Ludwigs-Universität Freiburg, Albertstr. 21, 79104, Freiburg, Germany., Loenarz C; Institut für Pharmazeutische Wissenschaften, Pharmazeutische und Medizinische Chemie, Albert-Ludwigs-Universität Freiburg, Albertstr. 25, 79104, Freiburg, Germany., Layer G; Institut für Pharmazeutische Wissenschaften, Pharmazeutische Biologie, Albert-Ludwigs-Universität Freiburg, Stefan-Meier-Str. 19, 79104, Freiburg, Germany.
Publikováno v: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2022 Aug 08; Vol. 61 (32), pp. e202204198. Date of Electronic Publication: 2022 Jun 29.
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7
Akademický článek
Human prolyl hydroxylase domain 2 reacts with O2 and 2-oxoglutarate to enable formation of inactive Fe(III).2OG.hypoxia-inducible-factor α complexes.
Autor: Fiorini, Giorgia1 (AUTHOR), Marshall, Stephen A.1 (AUTHOR), Figg Jr., William D.1 (AUTHOR), Myers, William K.2 (AUTHOR), Brewitz, Lennart1 (AUTHOR), Schofield, Christopher J.1 (AUTHOR) christopher.schofield@chem.ox.ac.uk
Publikováno v: Scientific Reports. 10/30/2024, Vol. 14 Issue 1, p1-17. 17p.
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8
Akademický článek
An Oxygen Sensation: Progress in Macromolecule Hydroxylation Triggered by the Elucidation of Cellular Oxygen Sensing.
Autor: Loenarz C; Institute of Pharmaceutical Sciences, Albert Ludwig University of Freiburg, Albertstr. 25, 79104, Freiburg, Germany.
Publikováno v: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2020 Mar 02; Vol. 59 (10), pp. 3776-3780. Date of Electronic Publication: 2020 Jan 21.
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9
Akademický článek
Complicated role of ALKBH5 in gastrointestinal cancer: an updated review.
Autor: Shu, Weitong1,2 (AUTHOR), Huang, Qianying1,2 (AUTHOR), Chen, Rui1,2 (AUTHOR), Lan, Huatao1,2 (AUTHOR), Yu, Luxin1,2 (AUTHOR), Cui, Kai1,2 (AUTHOR), He, Wanjun1,2 (AUTHOR), Zhu, Songshan1,2 (AUTHOR), Chen, Mei1,2 (AUTHOR), Li, Li1,2 (AUTHOR), Jiang, Dan1,2 (AUTHOR) jiangdan@gdmu.edu.cn, Xu, Guangxian1,2 (AUTHOR) xuguangxian@gdmu.edu.cn
Publikováno v: Cancer Cell International. 8/24/2024, Vol. 24 Issue 1, p1-11. 11p.
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10
Akademický článek
Gamma-glutamyl transferase secreted by Helicobacter pylori promotes the development of gastric cancer by affecting the energy metabolism and histone methylation status of gastric epithelial cells.
Autor: Jiang, Xin1 (AUTHOR), Wang, Weijun1 (AUTHOR), Wang, Zeyu1 (AUTHOR), Wang, Zhe1 (AUTHOR), Shi, Huiying1 (AUTHOR), Meng, Lingjun1 (AUTHOR), Pang, Suya1 (AUTHOR), Fan, Mengke1 (AUTHOR), Lin, Rong1 (AUTHOR) linrong@hust.edu.cn
Publikováno v: Cell Communication & Signaling. 8/15/2024, Vol. 22 Issue 1, p1-22. 22p.
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