Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Lodewyk F Wessels"'
Autor:
Kristel Kemper, Oscar Krijgsman, Paulien Cornelissen‐Steijger, Aida Shahrabi, Fleur Weeber, Ji‐Ying Song, Thomas Kuilman, Daniel J Vis, Lodewyk F Wessels, Emile E Voest, Ton NM Schumacher, Christian U Blank, David J Adams, John B Haanen, Daniel S Peeper
Publikováno v:
EMBO Molecular Medicine, Vol 7, Iss 9, Pp 1104-1118 (2015)
Abstract The development of targeted inhibitors, like vemurafenib, has greatly improved the clinical outcome of BRAFV600E metastatic melanoma. However, resistance to such compounds represents a formidable problem. Using whole‐exome sequencing and f
Externí odkaz:
https://doaj.org/article/8743728c73b5476d9e877b496d1b360e
Autor:
Adrian C. Begg, Marcel Verheij, Michiel W.M. van den Brekel, Hein te Riele, Ron Kerkhoven, Lodewyk F. Wessels, Reidar Grénman, Jelle J. ten Hoeve, Monique C. de Jong
Supplementary Figure 1 and Tables 1-8. Supplementary figure 1. Heatmap of common response, 2 and 6 hours after irradiation. Heatmap of the common response to 4 Gy irradiation in all 32 cell lines, adapted from the BRB-array tools time course plug-in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85c75d76e59327c9a6632145004d999f
https://doi.org/10.1158/1078-0432.22460798.v1
https://doi.org/10.1158/1078-0432.22460798.v1
Autor:
Adrian C. Begg, Marcel Verheij, Michiel W.M. van den Brekel, Hein te Riele, Ron Kerkhoven, Lodewyk F. Wessels, Reidar Grénman, Jelle J. ten Hoeve, Monique C. de Jong
Supplementary Information. This file contains a text file with the interactions between miRs and mRNAs used for the analyses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86459a1a7fd7e7b93db1cf1973b48578
https://doi.org/10.1158/1078-0432.22460795
https://doi.org/10.1158/1078-0432.22460795
Autor:
Adrian C. Begg, Marcel Verheij, Michiel W.M. van den Brekel, Hein te Riele, Ron Kerkhoven, Lodewyk F. Wessels, Reidar Grénman, Jelle J. ten Hoeve, Monique C. de Jong
Purpose: Predominant causes of head and neck cancer recurrence after radiotherapy are rapid repopulation, hypoxia, fraction of cancer stem cells, and intrinsic radioresistance. Currently, intrinsic radioresistance can only be assessed by ex vivo colo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3921aee5c179bb9b506e07f368a84821
https://doi.org/10.1158/1078-0432.c.6524594.v1
https://doi.org/10.1158/1078-0432.c.6524594.v1
Autor:
Kees Jalink, Frank N. van Leeuwen, Paul N. Span, Peter Bult, Fred C.G.J. Sweep, Lodewyk F. Wessels, Wilbert Zwart, Sander V. Canisius, Bé Wieringa, Remco van Horssen, Ilse Eidhof, Daan Visser, Linda Henneman, Arthur J. Kuipers, Jeroen Middelbeek
PDF file - 114K, Uncropped immunoblots and autoradiograms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a89df7cba3e3c9743f858681131479c7
https://doi.org/10.1158/0008-5472.22391468
https://doi.org/10.1158/0008-5472.22391468
Autor:
Kees Jalink, Frank N. van Leeuwen, Paul N. Span, Peter Bult, Fred C.G.J. Sweep, Lodewyk F. Wessels, Wilbert Zwart, Sander V. Canisius, Bé Wieringa, Remco van Horssen, Ilse Eidhof, Daan Visser, Linda Henneman, Arthur J. Kuipers, Jeroen Middelbeek
PDF file - 54K, TRPM7 shRNA#2 treatment reduces malignant phenotype of MDA-MB-231 cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::715cc78a45e64242b0fc2be64ee73a64
https://doi.org/10.1158/0008-5472.22391474
https://doi.org/10.1158/0008-5472.22391474
Autor:
Kees Jalink, Frank N. van Leeuwen, Paul N. Span, Peter Bult, Fred C.G.J. Sweep, Lodewyk F. Wessels, Wilbert Zwart, Sander V. Canisius, Bé Wieringa, Remco van Horssen, Ilse Eidhof, Daan Visser, Linda Henneman, Arthur J. Kuipers, Jeroen Middelbeek
PDF file - 643K, Rho-kinase inhibition rescues contractile and migratory phenotype of TRPM7 shRNA cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83479f9f2f87545dbb9f8b57ca3c7f89
https://doi.org/10.1158/0008-5472.22391471
https://doi.org/10.1158/0008-5472.22391471
Autor:
Kees Jalink, Frank N. van Leeuwen, Paul N. Span, Peter Bult, Fred C.G.J. Sweep, Lodewyk F. Wessels, Wilbert Zwart, Sander V. Canisius, Bé Wieringa, Remco van Horssen, Ilse Eidhof, Daan Visser, Linda Henneman, Arthur J. Kuipers, Jeroen Middelbeek
PDF file - 3.9MB, TRPM7 knockdown does not affect MDA-MB-231 cell proliferation but impairs metastasis formation in vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e281d902da8e07439e5758cdb5bed58a
https://doi.org/10.1158/0008-5472.22391477
https://doi.org/10.1158/0008-5472.22391477
Autor:
Kees Jalink, Frank N. van Leeuwen, Paul N. Span, Peter Bult, Fred C.G.J. Sweep, Lodewyk F. Wessels, Wilbert Zwart, Sander V. Canisius, Bé Wieringa, Remco van Horssen, Ilse Eidhof, Daan Visser, Linda Henneman, Arthur J. Kuipers, Jeroen Middelbeek
TRPM7 encodes a Ca2+-permeable nonselective cation channel with kinase activity. TRPM7 has been implicated in control of cell adhesion and migration, but whether TRPM7 activity contributes to cancer progression has not been established. Here we repor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac63bd0966d9d9a6b01fcc527adc9f08
https://doi.org/10.1158/0008-5472.c.6503270.v1
https://doi.org/10.1158/0008-5472.c.6503270.v1
Autor:
Kees Jalink, Frank N. van Leeuwen, Paul N. Span, Peter Bult, Fred C.G.J. Sweep, Lodewyk F. Wessels, Wilbert Zwart, Sander V. Canisius, Bé Wieringa, Remco van Horssen, Ilse Eidhof, Daan Visser, Linda Henneman, Arthur J. Kuipers, Jeroen Middelbeek
PDF file - 96K, TRPM7 expression levels and clinical parameters
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d5cf22ec65998c14ba082b303349be4
https://doi.org/10.1158/0008-5472.22391459
https://doi.org/10.1158/0008-5472.22391459