Zobrazeno 1 - 10
of 145
pro vyhledávání: '"Lodewijk W. van Rhijn"'
Autor:
Esther R.C. Janssen, Ilona M. Punt, Johan van Soest, Yvonne F. Heerkens, Hillegonda A. Stallinga, Huib ten Napel, Lodewijk W. van Rhijn, Barend Mons, Andre Dekker, Paul C. Willems, Nico L.U. van Meeteren
Publikováno v:
BMC Medical Informatics and Decision Making, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract An ever-increasing amount of data on a person’s daily functioning is being collected, which holds information to revolutionize person-centered healthcare. However, the full potential of data on daily functioning cannot yet be exploited as
Externí odkaz:
https://doaj.org/article/bed68761d8224ade96c790aaa56a5c44
Autor:
Mandy M.F. Steinbusch, Guus G.H. van den Akker, Andy Cremers, Adhiambo M.A. Witlox, Heleen M. Staal, Mandy J. Peffers, Lodewijk W. van Rhijn, Marjolein M.J. Caron, Tim J.M. Welting
Publikováno v:
Non-coding RNA Research, Vol 7, Iss 2, Pp 55-65 (2022)
Introduction: Ribosome biogenesis is integrated with many cellular processes including proliferation, differentiation and oncogenic events. Chondrogenic proliferation and differentiation require a high cellular translational capacity to facilitate ca
Externí odkaz:
https://doaj.org/article/bb29e52f629949dba5afb57af8b7828c
Autor:
Alzbeta Chabronova, Guus van den Akker, Bas A. C. Housmans, Marjolein M. J. Caron, Andy Cremers, Don A. M. Surtel, Mandy J. Peffers, Lodewijk W. van Rhijn, Virginie Marchand, Yuri Motorin, Tim J. M. Welting
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 16, p 12578 (2023)
Eukaryotic ribosomes are complex molecular nanomachines translating genetic information from mRNAs into proteins. There is natural heterogeneity in ribosome composition. The pseudouridylation (ψ) of ribosomal RNAs (rRNAs) is one of the key sources o
Externí odkaz:
https://doaj.org/article/f79530137c2145ee8eaffd0161a54d5d
Autor:
Alzbeta Chabronova, Guus G.H. van den Akker, Mandy M.F. Meekels-Steinbusch, Franziska Friedrich, Andy Cremers, Don A.M. Surtel, Mandy J. Peffers, Lodewijk W. van Rhijn, Ekkehart Lausch, Bernhard Zabel, Marjolein M.J. Caron, Tim J.M. Welting
Publikováno v:
Non-coding RNA Research, Vol 6, Iss 4, Pp 211-224 (2021)
Mutations in the non-coding snoRNA component of mitochondrial RNA processing endoribonuclease (RMRP) are the cause of cartilage-hair hypoplasia (CHH). CHH is a rare form of metaphyseal chondrodysplasia characterized by disproportionate short stature
Externí odkaz:
https://doaj.org/article/d37c8f7d561c4191a6c92acb6d382bcf
Autor:
Ellen G. J. Ripmeester, Marjolein M. J. Caron, Guus G. H. van den Akker, Jessica Steijns, Don A. M. Surtel, Andy Cremers, Laura C. W. Peeters, Lodewijk W. van Rhijn, Tim J. M. Welting
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract The fibrocartilage chondrocyte phenotype has been recognized to attribute to osteoarthritis (OA) development. These chondrocytes express genes related to unfavorable OA outcomes, emphasizing its importance in OA pathology. BMP7 is being expl
Externí odkaz:
https://doaj.org/article/01cfdb8fb7d54afe8a50c8e5b9da0ebe
Autor:
Marjolein M.J. Caron, Ellen G.J. Ripmeester, Guus van den Akker, Nina K.A. P. Wijnands, Jessica Steijns, Don A.M. Surtel, Andy Cremers, Pieter J. Emans, Lodewijk W. van Rhijn, Tim J.M. Welting
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 21, Iss , Pp 247-261 (2021)
Treatment of osteoarthritis (OA) is mainly symptomatic by alleviating pain to postpone total joint replacement. Bone morphogenetic protein 7 (BMP7) is a candidate morphogen for experimental OA treatment that favorably alters the chondrocyte and carti
Externí odkaz:
https://doaj.org/article/fe01f116b8f2411686d416b75c812172
Autor:
Ellen G. J. Ripmeester, Tim J. M. Welting, Guus G. H. van den Akker, Don A. M. Surtel, Jessica S. J. Steijns, Andy Cremers, Lodewijk W. van Rhijn, Marjolein M. J. Caron
Publikováno v:
PLoS ONE, Vol 17, Iss 2 (2022)
BMP7 is a morphogen capable of counteracting the OA chondrocyte hypertrophic phenotype via NKX3-2. NKX3-2 represses expression of RUNX2, an important transcription factor for chondrocyte hypertrophy. Since RUNX2 has previously been described as an in
Externí odkaz:
https://doaj.org/article/68066cf15959463cbf6882b07c7b2fb3
Autor:
Lotte Deirdre Elizabeth Dingena Maria Smals, Marcus Hubertus Harrietta Maria Hulsbosch, Sjoerd Ian Patrick Jozef de Faber, Jacobus J.C. Arts, Lodewijk W. van Rhijn, Paul Cornelis Willems
Publikováno v:
North American Spine Society Journal, Vol 8, Iss , Pp 100085- (2021)
Background: Post-Market Clinical Follow-Up has been integrated into the new Medical Device Regulations since 2020. The CD Horizon Solera 4.75 mm instrumentation (CD-Solera) was introduced worldwide in 2009, and specifically intended for surgical trea
Externí odkaz:
https://doaj.org/article/512e9c49525648f4905834c5f2b7e63e
Autor:
Marjolein M. J. Caron, Maxime Eveque, Berta Cillero-Pastor, Ron M. A. Heeren, Bas Housmans, Kasper Derks, Andy Cremers, Mandy J. Peffers, Lodewijk W. van Rhijn, Guus van den Akker, Tim J. M. Welting
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
IntroductionIn addition to the well-known cartilage extracellular matrix-related expression of Sox9, we demonstrated that chondrogenic differentiation of progenitor cells is driven by a sharply defined bi-phasic expression of Sox9: an immediate early
Externí odkaz:
https://doaj.org/article/29467c415e404b3c97d0e75e58695b9e
Autor:
Freek Hollman, M.D., Wanda M. de Raadt, M.Sc., Nienke Wolterbeek, Ph.D., Lodewijk W. van Rhijn, Ph.D., M.D., Kiem G. Auw Yang, Ph.D., M.D.
Publikováno v:
Arthroscopy, Sports Medicine, and Rehabilitation, Vol 3, Iss 2, Pp e521-e526 (2021)
Purpose: To assess the interchangeability of various existing answering scales within the subjective part of the Constant–Murley Score (CMS) and to determine the effect of the different answering scales on the inter- and intraobserver reliability.
Externí odkaz:
https://doaj.org/article/95bbbd414fee4f33849b2eee3a97ffa8