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Small Molecules Targeting Mycobacterium tuberculosis Type II NADH Dehydrogenase Exhibit Antimycobacterial Activity.

Autor: Harbut MB; California Institute for Biomedical Research, La Jolla, CA, 92037, USA., Yang B; California Institute for Biomedical Research, La Jolla, CA, 92037, USA., Liu R; California Institute for Biomedical Research, La Jolla, CA, 92037, USA., Yano T; Department of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Vilchèze C; Howard Hughes Medical Institute, Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY, 10461, USA., Cheng B; California Institute for Biomedical Research, La Jolla, CA, 92037, USA., Lockner J; California Institute for Biomedical Research, La Jolla, CA, 92037, USA., Guo H; Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China., Yu C; California Institute for Biomedical Research, La Jolla, CA, 92037, USA., Franzblau SG; Institute for Tuberculosis Research, University of Illinois at Chicago, Chicago, IL, 60612, USA., Petrassi HM; California Institute for Biomedical Research, La Jolla, CA, 92037, USA., Jacobs WR Jr; Howard Hughes Medical Institute, Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY, 10461, USA., Rubin H; Department of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Chatterjee AK; California Institute for Biomedical Research, La Jolla, CA, 92037, USA., Wang F; Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.; California Institute for Biomedical Research, La Jolla, CA, 92037, USA.

Publikováno v: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2018 Mar 19; Vol. 57 (13), pp. 3478-3482. Date of Electronic Publication: 2018 Feb 22.