The Role of Lysosomes in a Broad Disease-Modifying Approach Evaluated across Transgenic Mouse Models of Alzheimer's Disease and Parkinson's Disease and Models of Mild Cognitive Impairment.

Autor: Hwang J; William C. Friday Laboratory, Biotechnology Research and Training Center, University of North Carolina-Pembroke, Pembroke, NC 28372, USA.; Department of Pharmaceutical Sciences and the Neurosciences Program, University of Connecticut, Storrs, CT 06269, USA., Estick CM; Department of Pharmaceutical Sciences and the Neurosciences Program, University of Connecticut, Storrs, CT 06269, USA.; Department of Physiology and Neurobiology, University of Connecticut, Storrs, CT 06269, USA., Ikonne US; William C. Friday Laboratory, Biotechnology Research and Training Center, University of North Carolina-Pembroke, Pembroke, NC 28372, USA., Butler D; Department of Pharmaceutical Sciences and the Neurosciences Program, University of Connecticut, Storrs, CT 06269, USA.; Center for Drug Discovery, Northeastern University, Boston, MA 02115, USA., Pait MC; William C. Friday Laboratory, Biotechnology Research and Training Center, University of North Carolina-Pembroke, Pembroke, NC 28372, USA.; Department of Chemistry and Physics, University of North Carolina-Pembroke, Pembroke, NC 28372, USA., Elliott LH; William C. Friday Laboratory, Biotechnology Research and Training Center, University of North Carolina-Pembroke, Pembroke, NC 28372, USA.; Department of Biology, University of North Carolina-Pembroke, Pembroke, NC 28372, USA., Ruiz S; William C. Friday Laboratory, Biotechnology Research and Training Center, University of North Carolina-Pembroke, Pembroke, NC 28372, USA.; Department of Biology, University of North Carolina-Pembroke, Pembroke, NC 28372, USA., Smith K; William C. Friday Laboratory, Biotechnology Research and Training Center, University of North Carolina-Pembroke, Pembroke, NC 28372, USA.; Molecular Biotechnology Program University of North Carolina-Pembroke, Pembroke, NC 28372, USA., Rentschler KM; William C. Friday Laboratory, Biotechnology Research and Training Center, University of North Carolina-Pembroke, Pembroke, NC 28372, USA., Mundell C; William C. Friday Laboratory, Biotechnology Research and Training Center, University of North Carolina-Pembroke, Pembroke, NC 28372, USA.; Department of Biology, University of North Carolina-Pembroke, Pembroke, NC 28372, USA., Almeida MF; William C. Friday Laboratory, Biotechnology Research and Training Center, University of North Carolina-Pembroke, Pembroke, NC 28372, USA., Stumbling Bear N; William C. Friday Laboratory, Biotechnology Research and Training Center, University of North Carolina-Pembroke, Pembroke, NC 28372, USA.; Department of Biology, University of North Carolina-Pembroke, Pembroke, NC 28372, USA., Locklear JP; William C. Friday Laboratory, Biotechnology Research and Training Center, University of North Carolina-Pembroke, Pembroke, NC 28372, USA.; Department of Biology, University of North Carolina-Pembroke, Pembroke, NC 28372, USA., Abumohsen Y; William C. Friday Laboratory, Biotechnology Research and Training Center, University of North Carolina-Pembroke, Pembroke, NC 28372, USA.; Department of Biology, University of North Carolina-Pembroke, Pembroke, NC 28372, USA., Ivey CM; William C. Friday Laboratory, Biotechnology Research and Training Center, University of North Carolina-Pembroke, Pembroke, NC 28372, USA.; Department of Biology, University of North Carolina-Pembroke, Pembroke, NC 28372, USA., Farizatto KLG; William C. Friday Laboratory, Biotechnology Research and Training Center, University of North Carolina-Pembroke, Pembroke, NC 28372, USA.; Department of Biology, University of North Carolina-Pembroke, Pembroke, NC 28372, USA., Bahr BA; William C. Friday Laboratory, Biotechnology Research and Training Center, University of North Carolina-Pembroke, Pembroke, NC 28372, USA. bahr@uncp.edu.; Department of Pharmaceutical Sciences and the Neurosciences Program, University of Connecticut, Storrs, CT 06269, USA. bahr@uncp.edu.; Department of Physiology and Neurobiology, University of Connecticut, Storrs, CT 06269, USA. bahr@uncp.edu.; Department of Chemistry and Physics, University of North Carolina-Pembroke, Pembroke, NC 28372, USA. bahr@uncp.edu.; Department of Biology, University of North Carolina-Pembroke, Pembroke, NC 28372, USA. bahr@uncp.edu.; Molecular Biotechnology Program University of North Carolina-Pembroke, Pembroke, NC 28372, USA. bahr@uncp.edu.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2019 Sep 09; Vol. 20 (18). Date of Electronic Publication: 2019 Sep 09.