Zobrazeno 1 - 10
of 2 126
pro vyhledávání: '"Locker, A. P."'
Autor:
Zhiping Hu, Takeshi Kurihara, Yiyue Sun, Zeliha Cetin, Rodrigo M. Florentino, Lanuza A. P. Faccioli, Zhenghao Liu, Bo Yang, Alina Ostrowska, Joseph D. Locker, Alejandro Soto-Gutierrez, Evan R. Delgado
Publikováno v:
Frontiers in Gastroenterology, Vol 3 (2024)
Hepatocellular carcinoma (HCC) is a leading cause of cancer-related deaths, and commonly associated with hepatic fibrosis or cirrhosis. This study aims to establish a rat model mimicking the progression from liver fibrosis to cirrhosis and subsequent
Externí odkaz:
https://doaj.org/article/0ba87285b6114e80a427824b190da594
Publikováno v:
Current Issues in Sport Science, Vol 9, Iss 4 (2024)
Introduction & Purpose The idea of some athletes having high strength levels but being too slow for a particular movement while others are fast but not strong enough for the demands of their sport exists among many coaches. Therefore, planning deci
Externí odkaz:
https://doaj.org/article/6eb0a186c73d4be48fed02ae68d82c05
Autor:
Juliette Bitard, Elodie-Kim Grellier, Sophie Lourdel, Helena Prior Filipe, Annaïg Hamon, François Fenaille, Florence Anne Castelli, Emeline Chu-Van, Jérôme E. Roger, Morgane Locker, Muriel Perron
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-14 (2024)
Abstract Glaucoma is a multifactorial neurodegenerative disease characterized by the progressive and irreversible degeneration of the optic nerve and retinal ganglion cells. Despite medical advances aiming at slowing degeneration, around 40% of treat
Externí odkaz:
https://doaj.org/article/5094564ec34949d59e846b3ed1d20852
Autor:
Marta Melis, Rebecca Marino, Jianmin Tian, Carla Johnson, Rahil Sethi, Michael Oertel, Ira J. Fox, Joseph Locker
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 17, Iss 3, Pp 453-479 (2024)
Background & Aims: HNF4α, a master regulator of liver development and the mature hepatocyte phenotype, is down-regulated in chronic and inflammatory liver disease. We used contemporary transcriptomics and epigenomics to study the cause and effects o
Externí odkaz:
https://doaj.org/article/270e6dc5cdb04a1fb26e7c7fe9fb3567
Autor:
Vera Magg, Alessandro Manetto, Katja Kopp, Chia Ching Wu, Mohsen Naghizadeh, Doris Lindner, Lucy Eke, Julia Welsch, Stefan M. Kallenberger, Johanna Schott, Volker Haucke, Nicolas Locker, Georg Stoecklin, Alessia Ruggieri
Publikováno v:
Cell Reports, Vol 43, Iss 4, Pp 114069- (2024)
Summary: The integrated stress response (ISR) is a key cellular signaling pathway activated by environmental alterations that represses protein synthesis to restore homeostasis. To prevent sustained damage, the ISR is counteracted by the upregulation
Externí odkaz:
https://doaj.org/article/57ac933c39544e17ab8442346bf13c6f
Publikováno v:
Retrovirology, Vol 20, Iss 1, Pp 1-16 (2023)
Abstract Background Using pigs as organ donors has advanced xenotransplantation to the point that it is almost ready for clinical use. However, there is still a zoonotic risk associated with xenotransplantation, and the potential transmission of porc
Externí odkaz:
https://doaj.org/article/ba46416a88054d5ebdcb608cf393b5a1
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract The role of taurine in the treatment of congestive heart failure (CHF) in dogs without systemic deficiency is unexplored. Taurine might have beneficial cardiac effects aside from deficit replacement. We hypothesized that oral taurine supplem
Externí odkaz:
https://doaj.org/article/2c6182e4acfd438faff6ed2ddf325c41
Autor:
Shehnaz Bano, Matthew A. Copeland, John W. Stoops, Anne Orr, Siddhi Jain, Shirish Paranjpe, Raja Gopal Reddy Mooli, Sadeesh K. Ramakrishnan, Joseph Locker, Wendy M. Mars, George K. Michalopoulos, Bharat Bhushan
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 18, Iss 4, Pp 101380- (2024)
Background & Aims: Metabolic dysfunction-associated steatotic liver disease (MASLD) has become the most prevalent chronic liver disorder, with no approved treatment. Our previous work demonstrated the efficacy of a pan-ErbB inhibitor, Canertinib, in
Externí odkaz:
https://doaj.org/article/f29f693fd932476384c13a2ebe3c29a5
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Akademický článek
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