Oatp (Organic Anion Transporting Polypeptide)-Mediated Transport: A Mechanism for Atorvastatin Neuroprotection in Stroke.

Autor: Williams EI; Department of Pharmacology, College of Medicine, University of Arizona, Tucson., Betterton RD; Department of Pharmacology, College of Medicine, University of Arizona, Tucson., Stanton JA; Department of Pharmacology, College of Medicine, University of Arizona, Tucson., Moreno-Rodriguez VM; Department of Pharmacology, College of Medicine, University of Arizona, Tucson., Lochhead JJ; Department of Pharmacology, College of Medicine, University of Arizona, Tucson., Davis TP; Department of Pharmacology, College of Medicine, University of Arizona, Tucson., Ronaldson PT; Department of Pharmacology, College of Medicine, University of Arizona, Tucson.

Publikováno v: Stroke [Stroke] 2023 Nov; Vol. 54 (11), pp. 2875-2885. Date of Electronic Publication: 2023 Sep 26.

Regulation of Blood-Brain Barrier Transporters by Transforming Growth Factor- β /Activin Receptor-Like Kinase 1 Signaling: Relevance to the Brain Disposition of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibitors (i.e., Statins).

Autor: Betterton RD; Department of Pharmacology, College of Medicine, University of Arizona, Tucson, Arizona., Abdullahi W; Department of Pharmacology, College of Medicine, University of Arizona, Tucson, Arizona., Williams EI; Department of Pharmacology, College of Medicine, University of Arizona, Tucson, Arizona., Lochhead JJ; Department of Pharmacology, College of Medicine, University of Arizona, Tucson, Arizona., Brzica H; Department of Pharmacology, College of Medicine, University of Arizona, Tucson, Arizona., Stanton J; Department of Pharmacology, College of Medicine, University of Arizona, Tucson, Arizona., Reddell E; Department of Pharmacology, College of Medicine, University of Arizona, Tucson, Arizona., Ogbonnaya C; Department of Pharmacology, College of Medicine, University of Arizona, Tucson, Arizona., Davis TP; Department of Pharmacology, College of Medicine, University of Arizona, Tucson, Arizona., Ronaldson PT; Department of Pharmacology, College of Medicine, University of Arizona, Tucson, Arizona pronald@email.arizona.edu.

Publikováno v: Drug metabolism and disposition: the biological fate of chemicals [Drug Metab Dispos] 2022 Jul; Vol. 50 (7), pp. 942-956. Date of Electronic Publication: 2022 May 03.

β IV -spectrin as a stalk cell-intrinsic regulator of VEGF signaling.

Autor: Kwak EA; Department of Pharmacology, University of Arizona, Tucson, AZ, 85724, USA., Pan CC; Department of Pharmacology and Cancer Biology, Duke University, Durham, NC, 27710, USA., Ramonett A; Department of Pharmacology, University of Arizona, Tucson, AZ, 85724, USA., Kumar S; Division of Biology, Indian Institute of Science Education and Research, Tirupati, 517507, India., Cruz-Flores P; Department of Chemistry & Biochemistry, University of Arizona, Tucson, AZ, 85724, USA., Ahmed T; Department of Chemistry & Biochemistry, University of Arizona, Tucson, AZ, 85724, USA., Ortiz HR; Department of Pharmacology, University of Arizona, Tucson, AZ, 85724, USA., Lochhead JJ; Department of Pharmacology, University of Arizona, Tucson, AZ, 85724, USA., Ellis NA; Cellular and Molecular Medicine, University of Arizona, Tucson, AZ, 85724, USA., Mouneimne G; Cellular and Molecular Medicine, University of Arizona, Tucson, AZ, 85724, USA., Georgieva TG; BIO5 Institute, University of Arizona, Tucson, AZ, 85724, USA., Lee YS; Department of Pharmacology, University of Arizona, Tucson, AZ, 85724, USA., Vanderah TW; Department of Pharmacology, University of Arizona, Tucson, AZ, 85724, USA., Largent-Milnes T; Department of Pharmacology, University of Arizona, Tucson, AZ, 85724, USA., Mohler PJ; Department of Physiology and Cell Biology, Ohio State University, Columbus, OH, 43210, USA., Hund TJ; Department of Biomedical Engineering, Ohio State University, Columbus, OH, 43210, USA., Langlais PR; Department of Internal Medicine, University of Arizona, Tucson, AZ, 85724, USA., Mythreye K; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, 35294, USA., Lee NY; Department of Pharmacology, University of Arizona, Tucson, AZ, 85724, USA. namlee@email.arizona.edu.; Department of Chemistry & Biochemistry, University of Arizona, Tucson, AZ, 85724, USA. namlee@email.arizona.edu.; Cancer Center, University of Arizona, Tucson, AZ, 85724, USA. namlee@email.arizona.edu.

Publikováno v: Nature communications [Nat Commun] 2022 Mar 14; Vol. 13 (1), pp. 1326. Date of Electronic Publication: 2022 Mar 14.

Perivascular and Perineural Pathways Involved in Brain Delivery and Distribution of Drugs after Intranasal Administration.

Autor: Lochhead JJ; Department of Pharmacology, University of Arizona, Tucson, AZ 85721, USA., Davis TP; Department of Pharmacology, University of Arizona, Tucson, AZ 85721, USA.

Publikováno v: Pharmaceutics [Pharmaceutics] 2019 Nov 12; Vol. 11 (11). Date of Electronic Publication: 2019 Nov 12.

Delivery of immunoglobulin G antibodies to the rat nervous system following intranasal administration: Distribution, dose-response, and mechanisms of delivery.

Autor: Kumar NN; Pharmaceutical Sciences Division, University of Wisconsin-Madison School of Pharmacy, Madison, WI 53705, United States., Lochhead JJ; Pharmaceutical Sciences Division, University of Wisconsin-Madison School of Pharmacy, Madison, WI 53705, United States., Pizzo ME; Pharmaceutical Sciences Division, University of Wisconsin-Madison School of Pharmacy, Madison, WI 53705, United States; Clinical Neuroengineering Training Program, University of Wisconsin-Madison, Madison, WI 53705, United States., Nehra G; Pharmaceutical Sciences Division, University of Wisconsin-Madison School of Pharmacy, Madison, WI 53705, United States., Boroumand S; Pharmaceutical Sciences Division, University of Wisconsin-Madison School of Pharmacy, Madison, WI 53705, United States., Greene G; Pharmaceutical Sciences Division, University of Wisconsin-Madison School of Pharmacy, Madison, WI 53705, United States., Thorne RG; Pharmaceutical Sciences Division, University of Wisconsin-Madison School of Pharmacy, Madison, WI 53705, United States; Clinical Neuroengineering Training Program, University of Wisconsin-Madison, Madison, WI 53705, United States; Neuroscience Training Program & Center for Neuroscience, University of Wisconsin-Madison, Madison, WI 53705, United States; Cellular and Molecular Pathology Graduate Training Program, University of Wisconsin-Madison, Madison, WI 53705, United States. Electronic address: robert.thorne@wisc.edu.

Publikováno v: Journal of controlled release : official journal of the Controlled Release Society [J Control Release] 2018 Sep 28; Vol. 286, pp. 467-484. Date of Electronic Publication: 2018 Aug 04.