Amp(1q) and tetraploidy are commonly acquired chromosomal abnormalities in relapsed multiple myeloma

Autor: Locher, Maurus, Jukic, Emina, Vogi, Verena, Keller, Markus A, Kröll, Teresa, Schwendinger, Simon, Oberhuber, Klaus, Verdorfer, Irmgard, Mühlegger, Beatrix E, Witsch-Baumgartner, Martina, Nachbaur, David, Willenbacher, Wolfgang, Gunsilius, Eberhard, Wolf, Dominik, Zschocke, Johannes, Steiner, Normann

Publikováno v: Locher, Maurus; Jukic, Emina; Vogi, Verena; Keller, Markus A; Kröll, Teresa; Schwendinger, Simon; Oberhuber, Klaus; Verdorfer, Irmgard; Mühlegger, Beatrix E; Witsch-Baumgartner, Martina; Nachbaur, David; Willenbacher, Wolfgang; Gunsilius, Eberhard; Wolf, Dominik; Zschocke, Johannes; Steiner, Normann (2023). Amp(1q) and tetraploidy are commonly acquired chromosomal abnormalities in relapsed multiple myeloma. European journal of haematology, 110(3), pp. 296-304. Wiley 10.1111/ejh.13905

Long-term disease control in multiple myeloma (MM) is typically an unmet medical need, and most patients experience multiple relapses. Fluorescence in situ hybridization (FISH) is the standard technique to detect chromosomal abnormalities (CAs), whic

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https://doi.org/10.1111/ejh.13905

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The prognostic value of additional copies of 1q21 in multiple myeloma depends on the primary genetic event.

Autor: Locher, Maurus, Steurer, Michael, Jukic, Emina, Keller, Markus A., Fresser, Friedrich, Ruepp, Carmen, Wöll, Ewald, Verdorfer, Irmgard, Gastl, Günther, Willenbacher, Wolfgang, Weger, Roman, Nachbaur, David, Wolf, Dominik, Gunsilius, Eberhard, Zschocke, Johannes, Steiner, Normann

Publikováno v: American Journal of Hematology; Dec2020, Vol. 95 Issue 12, p1562-1571, 10p