Zobrazeno 1 - 1
of 1
pro vyhledávání: '"Loc T. Tran"'
Autor:
Vanasse Benoit J, Loc T. Tran, Juan Gamboa, Xuemin Chen, Timothy A. Ayers, Xiaodong Wu, Nakyen Choy, Rocco Disanto, Duane E. Rudisill, Duc P. Ngo, Ying Jiang, Geoffrey A. D'netto, Gardetto Anthony J, Sithamalli V. Chandramouli, David J. Lythgoe, Frederick Roberts, Narendra Kumar, Matthew R. Powers, Andrew W. Bridge, James H. Peers, Warren Copeland, Clive Pemberton
Publikováno v:
Organic Process Research & Development. 16:484-494
An enantioselective Overman 3,3-sigmatropic rearrangement on a quinuclidine skeleton was developed for the pilot-plant synthesis of a glycine transporter 1 inhibitor. The first stereocenter was produced by a Ru-catalyzed asymmetric transfer hydrogena