ALS-Related Mutant FUS Protein Is Mislocalized to Cytoplasm and Is Recruited into Stress Granules of Fibroblasts from Asymptomatic FUS P525L Mutation Carriers

Autor: Lo Bello M., Di Fini F., Notaro A., Spataro R., Conforti F.L., La Bella V.

Publikováno v: Neurodegenerative diseases
17 (2017): 292–303. doi:10.1159/000480085
info:cnr-pdr/source/autori:Lo Bello M.; Di Fini F.; Notaro A.; Spataro R.; Conforti F.L.; La Bella V./titolo:ALS-Related Mutant FUS Protein Is Mislocalized to Cytoplasm and Is Recruited into Stress Granules of Fibroblasts from Asymptomatic FUS P525L Mutation Carriers/doi:10.1159%2F000480085/rivista:Neurodegenerative diseases (Print)/anno:2017/pagina_da:292/pagina_a:303/intervallo_pagine:292–303/volume:17

Background: Amyotrophic lateral sclerosis (ALS) shows a strong genetic basis, with SOD1, FUS, TARDBP, and C9ORF72 being the genes most frequently involved. This has allowed identification of asymptomatic mutation carriers, which may be of help in und

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::6cf5510b2e6d053beedacd94e3075504
http://hdl.handle.net/10447/378861

Synergistic Inhibitory Effect of Gliquidone Against Cisplatin‐Resistant Human Lung Adenocarcinoma.

Autor: Qiu, Xi^1,2, Liu, Bo², Ye, Pan-Pan¹, Song, Lin-Lin¹, Zhang, Xue¹, Gu, Wei-Ping¹, Li, Ling¹, Zhu, Shun-Wei³, Zhao, Wei^1,4 zhao4wei2@hotmail.com, Yang, Xin-Mei¹ yangxinm1986@126.com, Silvestre, Samuel

Publikováno v: Journal of Clinical Pharmacy & Therapeutics. 11/15/2024, Vol. 2024, p1-13. 13p.

Biomarcatori di stress ossidativo nell'esposizione occupazionale a basse dosi di 1,3-butadiene

Autor: LO BELLO M., PRIMAVERA A., FUSTINONI S., FEDERICI G., MANNO, MAURIZIO

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3730::4198aac5af1af93117a04c4773171056
http://hdl.handle.net/11588/347551

Flexibility of helix 2 in the human glutathione transferase P1-1. time-resolved fluorescence spectroscopy

Autor: Stella, L, Caccuri, Am, Rosato, N, Nicotra, M, LO BELLO, M, DE MATTEIS, F, Mazzetti, A, Federici, G, Ricci, G

Publikováno v: The Journal of biological chemistry. 273(36)

Time-resolved fluorescence spectroscopy and site-directed mutagenesis have been used to probe the flexibility of alpha-helix 2 (residues 35-46) in the apo structure of the human glutathione transferase P1-1 (EC 2.5.1.18) as well as in the binary comp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::7baadafefaa32643b16496176feedfc2
https://pubmed.ncbi.nlm.nih.gov/9722558

Electrostatic association of glutathione transferase to the nuclear membrane: Evidence of a defense barrier at the nuclear envelope

Autor: STELLA L, MORENO S, LEONI S, DE MARIA F, TURELLA P, FEDERICI, G, FABRINI R, DAWOOD KF, LO BELLO M, PEDERSEN JZ, RICCI G., PALLOTTINI, Valentina

The possible nuclear compartmentalization of glutathione transferase isoenzymes has been the subject of contradictory reports. The discovery that the dinitrosyl-diglutathionyl-iron complex binds tightly to Alpha class GSTs in rat hepatocytes and that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3668::e7f1c38c7bc8c573e97ad6f5cfa8d25e
https://hdl.handle.net/11590/123130