Zobrazeno 1 - 10
of 134
pro vyhledávání: '"Löser, Reik"'
Autor:
Müller, Claudia Damaris, Ruiz-Gómez, Gloria, Cazzonelli, Sophie, Möller, Stephanie, Wodtke, Robert, Löser, Reik, Freyse, Joanna, Dürig, Jan-Niklas, Rademann, Jörg, Hempel, Ute, Pisabarro, M. Teresa, Vogel, Sarah
Transglutaminases (TGs) catalyze the covalent crosslinking of proteins via isopeptide bonds. The most prominent isoform, TG2, is associated with physiological processes such as extracellular matrix (ECM) stabilization and plays a crucial role in the
Externí odkaz:
https://tud.qucosa.de/id/qucosa%3A91663
https://tud.qucosa.de/api/qucosa%3A91663/attachment/ATT-0/
https://tud.qucosa.de/api/qucosa%3A91663/attachment/ATT-0/
Autor:
Ruiz-Gómez, Gloria, Hawkins, John C., Philipp, Jenny, Künze, Georg, Wodtke, Robert, Löser, Reik, Fahmy, Karim, Pisabarro, M. Teresa
Publikováno v:
PLOS ONE (2016), 11(4). ISSN 1932-6203. DOI: 10.1371/journal.pone.0154046
Tackling protein interfaces with small molecules capable of modulating protein-protein interactions remains a challenge in structure-based ligand design. Particularly arduous are cases in which the epitopes involved in molecular recognition have a no
Autor:
Ruiz-Gómez, Gloria, Hawkins, John C., Philipp, Jenny, Künze, Georg, Wodtke, Robert, Löser, Reik, Fahmy, Karim, Pisabarro, M. Teresa
Tackling protein interfaces with small molecules capable of modulating protein-protein interactions remains a challenge in structure-based ligand design. Particularly arduous are cases in which the epitopes involved in molecular recognition have a no
Externí odkaz:
https://tud.qucosa.de/id/qucosa%3A30052
https://tud.qucosa.de/api/qucosa%3A30052/attachment/ATT-0/
https://tud.qucosa.de/api/qucosa%3A30052/attachment/ATT-0/
Autor:
Wodtke, Robert, Ruiz-Gómez, Gloria, Kuchar, Manuela, Pisabarro, M. Teresa, Novotná, Pavlina, Urbanová, Marie, Steinbach, Jörg, Pietzsch, Jens, Löser, Reik
The collagen telopeptides play an important role for lysyl oxidase-mediated crosslinking, a process which is deregulated during tumour progression. The DEKS motif which is located within the N-terminal telopeptide of the α1 chain of type I collagen
Externí odkaz:
https://tud.qucosa.de/id/qucosa%3A36280
https://tud.qucosa.de/api/qucosa%3A36280/attachment/ATT-0/
https://tud.qucosa.de/api/qucosa%3A36280/attachment/ATT-0/
Autor:
Löser, Reik
In dieser Arbeit wird über die Entwicklung von neuartigen PET-Tracern für die In-vivo-Bildgebung von Cystein-Cathepsinen, Lysyloxidasen und Transglutaminase 2 als tumorassoziierte Matrix-modifizierende Enzyme berichtet. Dies beinhaltet im Einzelnen
Externí odkaz:
https://tud.qucosa.de/id/qucosa%3A84064
https://tud.qucosa.de/api/qucosa%3A84064/attachment/ATT-0/
https://tud.qucosa.de/api/qucosa%3A84064/attachment/ATT-0/
Akademický článek
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Autor:
Wodtke, Robert, Laube, Markus, Hauser, Sandra, Meister, Sebastian, Ludwig, Friedrich-Alexander, Fischer, Steffen, Kopka, Klaus, Pietzsch, Jens, Löser, Reik
Publikováno v:
EJNMMI Radiopharmacy & Chemistry; 1/2/2024, Vol. 8 Issue 1, p1-25, 25p
Autor:
Löser, Reik, Kuchar, Manuela, Wodtke, Robert, Neuber, Christin, Belter, Birgit, Kopka, Klaus, Santhanam, Lakshmi, Pietzsch, Jens
Publikováno v:
ChemMedChem; Sep2023, Vol. 18 Issue 18, p1-26, 26p
Publikováno v:
ACS Omega; 7/4/2023, Vol. 8 Issue 26, p24003-24009, 7p
Autor:
Behring, Lydia, Ruiz-Gómez, Gloria, Trapp, Christian, Morales, Maryann, Wodtke, Robert, Köckerling, Martin, Kopka, Klaus, Pisabarro, M. Teresa, Pietzsch, Jens, Löser, Reik
Publikováno v:
Journal of Medicinal Chemistry; 3/23/2023, Vol. 66 Issue 6, p3818-3851, 34p