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pro vyhledávání: '"Loïc Leroux"'
Autor:
Loïc Leroux
Baptiste, écrivain, doit rédiger un conte de fées en moins de quatre jours. Malheureusement, il n'a aucun souvenir des histoires de son enfance. Alors, tout en faisant face à l'opération chirurgicale de sa sœur jumelle et à la réapparition d'
Publikováno v:
EMBO Reports
EMBO Reports, EMBO Press, 2002, 3 (4), pp.323-328. ⟨10.1093/embo-reports/kvf078⟩
EMBO Reports, EMBO Press, 2002, 3 (4), pp.323-328. ⟨10.1093/embo-reports/kvf078⟩
Non-insulin-dependent diabetes mellitus (NIDDM) is a complex heterogeneous polygenic disease characterized mainly by insulin resistance and pancreatic beta-cell dysfunction. In recent years, several genetically engineered mouse models have been devel
Autor:
Danielle Bucchini, Gretta Abou Sleymane, Laëtitia Languille, Loïc Leroux, Alain Ktorza, Susan Saint-Just, Cécile Tourrel-Cuzin, Rajiv L. Joshi, Luciane Lamotte, Melis Karaca, Béatrice Durel
Publikováno v:
Frontiers in bioscience : a journal and virtual library
Frontiers in bioscience : a journal and virtual library, 2007, 12, pp.1586-1593
Frontiers in bioscience : a journal and virtual library, 2007, 12, pp.1586-1593
We have generated transgenic mouse lines expressing exclusively a human INS transgene on an Ins1/Ins2 double knockout (mIKO) background. The transgene expression was driven by either a 4000 bp or a 353 bp promoter. These transgenic lines, designated