Zobrazeno 1 - 10
of 12 637
pro vyhledávání: '"Lncap"'
Autor:
Chayisara Phongsuwichetsak, Thummaruk Suksrichavalit, Chawalit Chatupheeraphat, Warawan Eiamphungporn, Sakda Yainoy, Vichanan Yamkamon
Publikováno v:
PeerJ, Vol 12, p e17637 (2024)
Background Prostate cancer (PCa) is one of the causes of death in men worldwide. Although treatment strategies have been developed, the recurrence of the disease and consequential side effects remain an essential concern. Diospyros rhodocalyx Kurz, a
Externí odkaz:
https://doaj.org/article/7cb06068101e446abb1369413a657438
Autor:
Yang Liu, Li Xia, Haiyang Li, Ping Cai, Sufan Tang, Yue Feng, Guangfu Liu, Yue Chen, Nan Liu, Wei Zhang, Zhijun Zhou
Publikováno v:
EJNMMI Research, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Background Prostate cancer is the second most frequent cancer and the fifth leading cause of cancer-related deaths in men. Prostate-specific membrane antigen (PSMA) as a target has gained increasing attention. This research aims to investiga
Externí odkaz:
https://doaj.org/article/79b8f8e01ed142c2903c561102e9d2a7
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-16 (2023)
Abstract Background Prostate cancer is a common solid tumor that affects a significant number of men worldwide. Conventional androgen deprivation therapy (ADT) increases the risk of developing castration-resistant prostate cancer (CRPC). Effective cl
Externí odkaz:
https://doaj.org/article/04aaf5a814c040e0b2f4be549cf61093
Autor:
Luiza M. Balieiro, Maria Renata Valente Brandão Freire, Joel Mendes Santos, Elaine Bortoleti Araujo
Publikováno v:
Hematology, Transfusion and Cell Therapy, Vol 46, Iss , Pp S4-S5 (2024)
Introdução/Justificativa: O antígeno de membrana específico da próstata (PSMA) é uma glicoproteína de transmembrana do tipo II que se mostra baixa ou não é expressa na próstata normal, mas é altamente expressa no câncer e apresenta-se ain
Externí odkaz:
https://doaj.org/article/ab31a40679f8497a91a0bfef8567f70c
Publikováno v:
Biomolecules, Vol 14, Iss 7, p 811 (2024)
A new class of pyrazolylmethylene-2-thioxoimidazolidin-4-one derivatives 3a–p were rationally designed and synthesized with the aim of exploring their potential as treatments for prostate cancer. The synthesized compounds 3a–p were biologically a
Externí odkaz:
https://doaj.org/article/68c9758c128c4015b507e6f3d0a18112
Autor:
Gloria Cecilia Galvan, Nadine A. Friedrich, Sanjay Das, James P. Daniels, Sara Pollan, Shweta Dambal, Ryusuke Suzuki, Sergio E. Sanders, Sungyong You, Hisashi Tanaka, Yeon-Joo Lee, Wei Yuan, Johann S. de Bono, Irina Vasilevskaya, Karen E. Knudsen, Michael R. Freeman, Stephen J. Freedland
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionWe previously reported that cholesterol homeostasis in prostate cancer (PC) is regulated by 27-hydroxycholesterol (27HC) and that CYP27A1, the enzyme that converts cholesterol to 27HC, is frequently lost in PCs. We observed that restoring
Externí odkaz:
https://doaj.org/article/ec60d6dd2eac4bd18a56190427b615e9
Akademický článek
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Autor:
R. R. Khalikov, D. D. Gromenko, S. Sh. Galimova, K. V. Danilko, I. D. Gromenko, Sh. N. Galimov, P. F. Litvitsky
Publikováno v:
Креативная хирургия и онкология, Vol 12, Iss 2, Pp 118-122 (2022)
Background. Melittin is a major constituent of honeybee venom and comprises a water-soluble surfactant peptide with cytolytic effects potentially applicable in anticancer therapy. We evaluated the impact of melittin from Bashkir honeybee (Apis mellif
Externí odkaz:
https://doaj.org/article/dadd82e66e1a4af492065b1b21aad9f8
Autor:
Marc Wiesehöfer, Benedikt Bernhard Gereon Raczinski, Caroline Wiesehöfer, Jaroslaw Thomas Dankert, Elena Dilara Czyrnik, Martin Spahn, Marianna Kruithof-de Julio, Gunther Wennemuth
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionIn prostate cancer, long-term treatment directed against androgens often leads to the development of metastatic castration-resistant prostate cancer, which is more aggressive and not curatively treatable. Androgen deprivation results in e
Externí odkaz:
https://doaj.org/article/379c3b31c06f46b489dac201810d57d3
Autor:
Marchetti Carla
Publikováno v:
Biomolecular Concepts, Vol 13, Iss 1, Pp 156-163 (2022)
Calcium signaling controls a large variety of cell functions, including proliferation and apoptosis, and plays a major role in neoplastic transformation. Prostate cancer (PCa) is one of the most common malignancies in men. The transition to castratio
Externí odkaz:
https://doaj.org/article/babf18b67da5456b8a9feb446c1884d3