Molecular classification of human carcinomas by use of gene expression signatures

Autor: Ai, Su, Jb, Welsh, Lm, Sapinoso, Sg, Kern, Dimitrov P, Hilmar Lapp, Pg, Schultz, Sm, Powell, Ca, Moskaluk, Hf, Frierson Jr, Gm, Hampton

Publikováno v: Europe PubMed Central

Classification of human tumors according to their primary anatomical site of origin is fundamental for the optimal treatment of patients with cancer. Here we describe the use of large-scale RNA profiling and supervised machine learning algorithms to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::7fb42a7841f5e7eae22f703a05258eda
https://pubmed.ncbi.nlm.nih.gov/11606367

CC-115, a dual inhibitor of mTOR kinase and DNA-PK, blocks DNA damage repair pathways and selectively inhibits ATM-deficient cell growth in vitro .

Autor: Tsuji T; Oncology Research, Celgene Corporation, San Diego, CA 92121, USA., Sapinoso LM; Oncology Research, Celgene Corporation, San Diego, CA 92121, USA., Tran T; Oncology Research, Celgene Corporation, San Diego, CA 92121, USA., Gaffney B; Oncology Research, Celgene Corporation, San Diego, CA 92121, USA., Wong L; Oncology Research, Celgene Corporation, San Diego, CA 92121, USA., Sankar S; Oncology Research, Celgene Corporation, San Diego, CA 92121, USA., Raymon HK; Pharmacology, Celgene Corporation, San Diego, CA 92121, USA., Mortensen DS; Medicinal Chemistry, Celgene Corporation, San Diego, CA 92121, USA., Xu S; Oncology Research, Celgene Corporation, San Diego, CA 92121, USA.

Publikováno v: Oncotarget [Oncotarget] 2017 Aug 18; Vol. 8 (43), pp. 74688-74702. Date of Electronic Publication: 2017 Aug 18 (Print Publication: 2017).

Altered expression of TFF-1 and CES-2 in Barrett's Esophagus and associated adenocarcinomas.

Autor: Fox CA; Digestive Health Center of Excellence, Division of Gastroenterology and Hepatology, University of Virginia, Charlottesville, VA 22908, USA., Sapinoso LM, Zhang H, Zhang W, McLeod HL, Petroni GR, Mullick T, Moskaluk CA, Frierson HF, Hampton GM, Powell SM

Publikováno v: Neoplasia (New York, N.Y.) [Neoplasia] 2005 Apr; Vol. 7 (4), pp. 407-16.

Overexpression, genomic amplification and therapeutic potential of inhibiting the UbcH10 ubiquitin conjugase in human carcinomas of diverse anatomic origin.

Autor: Wagner KW; Genomics Institute of the Novartis Research Foundation, 10675 John Jay Hopkins Drive, San Diego, CA 92121, USA., Sapinoso LM, El-Rifai W, Frierson HF, Butz N, Mestan J, Hofmann F, Deveraux QL, Hampton GM

Publikováno v: Oncogene [Oncogene] 2004 Aug 26; Vol. 23 (39), pp. 6621-9.

Large-scale delineation of secreted protein biomarkers overexpressed in cancer tissue and serum.

Autor: Welsh JB; Genomics Institute of the Novartis Research Foundation, 10675 John Jay Hopkins Drive, San Diego, CA 92121, USA., Sapinoso LM, Kern SG, Brown DA, Liu T, Bauskin AR, Ward RL, Hawkins NJ, Quinn DI, Russell PJ, Sutherland RL, Breit SN, Moskaluk CA, Frierson HF Jr, Hampton GM

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2003 Mar 18; Vol. 100 (6), pp. 3410-5. Date of Electronic Publication: 2003 Mar 06.