Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Lluc Mosteiro"'
Autor:
Elena Senís, Lluc Mosteiro, Stefan Wilkening, Ellen Wiedtke, Ali Nowrouzi, Saira Afzal, Raffaele Fronza, Henrik Landerer, Maria Abad, Dominik Niopek, Manfred Schmidt, Manuel Serrano, Dirk Grimm
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
In vivo reprogramming of somatic cells is hampered by the need for vectors to express the OKSM factors in selected organs. Here the authors report new AAV-based vectors capable of in vivo reprogramming at low doses.
Externí odkaz:
https://doaj.org/article/097051282c3e433e8f3bfa8162e92d23
Autor:
Rosa M. Marión, Isabel López de Silanes, Lluc Mosteiro, Benjamin Gamache, María Abad, Carmen Guerra, Diego Megías, Manuel Serrano, Maria A. Blasco
Publikováno v:
Stem Cell Reports, Vol 8, Iss 2, Pp 460-475 (2017)
Reprogramming of differentiated cells into induced pluripotent stem cells has been recently achieved in vivo in mice. Telomeres are essential for chromosomal stability and determine organismal life span as well as cancer growth. Here, we study whethe
Externí odkaz:
https://doaj.org/article/826732fd428d47328b54828bdef6a1fa
Autor:
Oriol Calvete, Pablo Garcia‐Pavia, Fernando Domínguez, Lluc Mosteiro, Lucía Pérez‐Cabornero, Diego Cantalapiedra, Esther Zorio, Teresa Ramón y Cajal, Maria G. Crespo‐Leiro, Álex Teulé, Conxi Lázaro, Manuel M. Morente, Miguel Urioste, Javier Benitez
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 8, Iss 18 (2019)
Background Mutations in the POT1 gene explain abnormally long telomeres and multiple tumors including cardiac angiosarcomas (CAS). However, the link between long telomeres and tumorigenesis is poorly understood. Methods and Results Here, we have stud
Externí odkaz:
https://doaj.org/article/798ab5626f524e1a8629eaa7135e8845
Autor:
Lluc Mosteiro, Thi Thu Thao Nguyen, Simona Hankeova, Mike Reichelt, Shannon M. Vandriel, Zijuan Lai, Feroza K. Choudhury, Dewakar Sangaraju, Binita M. Kamath, Alexis Scherl, Robert Piskol, Christian W. Siebel
SUMMARYThe thyroid functions at the apex of a web of endocrine organs that control cell growth, differentiation and metabolic homeostasis. Thyroid dysregulation significantly impacts human health in myriad ways with thyroid diseases standing as the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e7ed0cff316755af9d1222447252822
https://doi.org/10.1101/2022.09.02.506441
https://doi.org/10.1101/2022.09.02.506441
Autor:
Dafni Chondronasiou, Diljeet Gill, Lluc Mosteiro, Rocio G. Urdinguio, Antonio Berenguer‐Llergo, Mònica Aguilera, Sylvere Durand, Fanny Aprahamian, Nitharsshini Nirmalathasan, Maria Abad, Daniel E. Martin‐Herranz, Camille Stephan‐Otto Attolini, Neus Prats, Guido Kroemer, Mario F. Fraga, Wolf Reik, Manuel Serrano
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Scopus
Scientia
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
Universidad de Barcelona
Scopus
Scientia
RUO. Repositorio Institucional de la Universidad de Oviedo
instname
The expression of the pluripotency factors OCT4, SOX2, KLF4, and MYC (OSKM) can convert somatic differentiated cells into pluripotent stem cells in a process known as reprogramming. Notably, partial and reversible reprogramming does not change cell i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6722cd36b3762c85823aa9111c6f1a6f
http://hdl.handle.net/2445/184013
http://hdl.handle.net/2445/184013
Autor:
Elena Melendez, Dafni Chondronasiou, Lluc Mosteiro, Jaime Martínez de Villarreal, Marcos Fernández-Alfara, Cian J. Lynch, Dirk Grimm, Francisco X. Real, José Alcamí, Núria Climent, Federico Pietrocola, Manuel Serrano
Publikováno v:
Repisalud
Instituto de Salud Carlos III (ISCIII)
Dipòsit Digital de la UB
Universidad de Barcelona
Instituto de Salud Carlos III (ISCIII)
Dipòsit Digital de la UB
Universidad de Barcelona
The ectopic expression of the transcription factors OCT4, SOX2, KLF4 and MYC (OSKM) enables reprogramming of differentiated cells into pluripotent embryonic stem cells. Methods based on partial and reversible in vivo reprogramming are a promising str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57725a4515a4dfa7ada1ad7f9e3ca927
http://hdl.handle.net/10230/53527
http://hdl.handle.net/10230/53527
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2318
Cellular reprogramming is a process by which adult differentiated cells lose their identity and are converted into pluripotent stem cells, known as induced pluripotent stem (iPS) cells. This process can be achieved in vitro and in vivo and is relevan
Publikováno v:
The Myc Gene ISBN: 9781071614754
Cellular reprogramming is a process by which adult differentiated cells lose their identity and are converted into pluripotent stem cells, known as induced pluripotent stem (iPS) cells. This process can be achieved in vitro and in vivo and is relevan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b184d635b72b297a7770baba7c99f988
https://doi.org/10.1007/978-1-0716-1476-1_14
https://doi.org/10.1007/978-1-0716-1476-1_14
Autor:
Dominik Niopek, Elena Senís, María Abad, Dirk Grimm, Stefan Wilkening, Saira Afzal, Henrik Landerer, Lluc Mosteiro, Ellen Wiedtke, Ali Nowrouzi, Raffaele Fronza, Manuel Serrano, Manfred Schmidt
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Repisalud
Instituto de Salud Carlos III (ISCIII)
Nature Communications
Repisalud
Instituto de Salud Carlos III (ISCIII)
Nature Communications
In vivo reprogramming of somatic cells into induced pluripotent stem cells (iPSC) holds vast potential for basic research and regenerative medicine. However, it remains hampered by a need for vectors to express reprogramming factors (Oct-3/4, Klf4, S
Autor:
Diego Megías, María Abad, Isabel López de Silanes, Carmen Guerra, Manuel Serrano, Lluc Mosteiro, Benjamin J. Gamache, Rosa M. Marión, Maria A. Blasco
Publikováno v:
Stem Cell Reports
Repisalud
Instituto de Salud Carlos III (ISCIII)
Stem Cell Reports, Vol 8, Iss 2, Pp 460-475 (2017)
Repisalud
Instituto de Salud Carlos III (ISCIII)
Stem Cell Reports, Vol 8, Iss 2, Pp 460-475 (2017)
Summary Reprogramming of differentiated cells into induced pluripotent stem cells has been recently achieved in vivo in mice. Telomeres are essential for chromosomal stability and determine organismal life span as well as cancer growth. Here, we stud