Zobrazeno 1 - 10
of 121
pro vyhledávání: '"Lluís Quintana-Murci"'
Autor:
Jacob Bergstedt, Sadoune Ait Kaci Azzou, Kristin Tsuo, Anthony Jaquaniello, Alejandra Urrutia, Maxime Rotival, David T. S. Lin, Julia L. MacIsaac, Michael S. Kobor, Matthew L. Albert, Darragh Duffy, Etienne Patin, Lluís Quintana-Murci, Milieu Intérieur Consortium
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
Many studies assess epigenetic marks in white blood cells, but it is unclear how much immune factors affect the epigenome. Here, the authors show that fine-scale blood cell composition and cytomegalovirus infection affect the DNA methylome of adults.
Externí odkaz:
https://doaj.org/article/d485673d79fb4ce58ac6fd1885bfaa9c
Autor:
Michael D Morgan, Etienne Patin, Bernd Jagla, Milena Hasan, Lluís Quintana-Murci, John C Marioni
Publikováno v:
PLoS Genetics, Vol 16, Iss 3, p e1008686 (2020)
Identifying the factors that shape protein expression variability in complex multi-cellular organisms has primarily focused on promoter architecture and regulation of single-cell expression in cis. However, this targeted approach has to date been una
Externí odkaz:
https://doaj.org/article/9e894bb2de694ec2a6fa46dde30a8111
Autor:
Lisa M McEwen, Meaghan J Jones, David Tse Shen Lin, Rachel D Edgar, Lucas T Husquin, Julia L MacIsaac, Katia E Ramadori, Alexander M Morin, Christopher F Rider, Chris Carlsten, Lluís Quintana-Murci, Steve Horvath, Michael S Kobor
Publikováno v:
Clinical Epigenetics, Vol 10, Iss 1, Pp 1-9 (2018)
Abstract Background The capacity of technologies measuring DNA methylation (DNAm) is rapidly evolving, as are the options for applicable bioinformatics methods. The most commonly used DNAm microarray, the Illumina Infinium HumanMethylation450 (450K a
Externí odkaz:
https://doaj.org/article/c7c9511d89d7403dbd78d2c6ae04b322
Autor:
Lluís Quintana-Murci
Der international renommierte Biologe Lluís Quintana-Murci zeichnet in dieser so bahnbrechenden wie meisterhaften Darstellung die außergewöhnliche Geschichte der menschlichen Besiedlung auf der ganzen Welt nach. Er belegt die Existenz ausgestorben
Autor:
Lluís Quintana-Murci
Publikováno v:
Molecular Analyses ISBN: 9781003247432
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c99fece5e95b93d1b0f4a954ce43a75
https://doi.org/10.1201/9781003247432-29
https://doi.org/10.1201/9781003247432-29
Autor:
Katherine J Siddle, Ludovic Tailleux, Matthieu Deschamps, Yong-Hwee Eddie Loh, Cécile Deluen, Brigitte Gicquel, Christophe Antoniewski, Luis B Barreiro, Laurent Farinelli, Lluís Quintana-Murci
Publikováno v:
PLoS Genetics, Vol 11, Iss 3, p e1005064 (2015)
The optimal coordination of the transcriptional response of host cells to infection is essential for establishing appropriate immunological outcomes. In this context, the role of microRNAs (miRNAs)--important epigenetic regulators of gene expression-
Externí odkaz:
https://doaj.org/article/e25d9dc2459747f0b43e82398aa101a5
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e10284 (2010)
BackgroundEstimating the historical and demographic parameters that characterize modern human populations is a fundamental part of reconstructing the recent history of our species. In addition, the development of a model of human evolution that can b
Externí odkaz:
https://doaj.org/article/57db441b1515459da89ec89a2ec8a64e
Autor:
Luis B Barreiro, Meriem Ben-Ali, Hélène Quach, Guillaume Laval, Etienne Patin, Joseph K Pickrell, Christiane Bouchier, Magali Tichit, Olivier Neyrolles, Brigitte Gicquel, Judith R Kidd, Kenneth K Kidd, Alexandre Alcaïs, Josiane Ragimbeau, Sandra Pellegrini, Laurent Abel, Jean-Laurent Casanova, Lluís Quintana-Murci
Publikováno v:
PLoS Genetics, Vol 5, Iss 7, p e1000562 (2009)
Infectious diseases have been paramount among the threats to health and survival throughout human evolutionary history. Natural selection is therefore expected to act strongly on host defense genes, particularly on innate immunity genes whose product
Externí odkaz:
https://doaj.org/article/3ba6c0b6158c402cbdd13c5ae03660c0
Autor:
Etienne Patin, Guillaume Laval, Luis B Barreiro, Antonio Salas, Ornella Semino, Silvana Santachiara-Benerecetti, Kenneth K Kidd, Judith R Kidd, Lolke Van der Veen, Jean-Marie Hombert, Antoine Gessain, Alain Froment, Serge Bahuchet, Evelyne Heyer, Lluís Quintana-Murci
Publikováno v:
PLoS Genetics, Vol 5, Iss 4, p e1000448 (2009)
The transition from hunting and gathering to farming involved a major cultural innovation that has spread rapidly over most of the globe in the last ten millennia. In sub-Saharan Africa, hunter-gatherers have begun to shift toward an agriculture-base
Externí odkaz:
https://doaj.org/article/2211778e2c534cd9b3185a09c5ab9eae
Publikováno v:
Medecine sciences : M/S. 32(12)
Throughout evolution, humans have had to face strong variation in environmental conditions, with pathogens being among the strongest threats that our species has encountered. The use of population genetic approaches provides novel insights into how n