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pro vyhledávání: '"Lloyd Yu"'
Autor:
Archana Belle, Frederick G. Hayden, Chad J. Roy, Keith L. Wycoff, James Maclean, Lloyd Yu, Y. Tran
Publikováno v:
Plant Biotechnology Journal
Immunoadhesins are recombinant proteins that combine the ligand-binding region of a receptor or adhesion molecule with immunoglobulin constant domains. All FDA-approved immunoadhesins are designed to modulate the interaction of a human receptor with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2317578fb509b85efc4e2af8c8034f8b
https://europepmc.org/articles/PMC4749143/
https://europepmc.org/articles/PMC4749143/
Publikováno v:
Biomolecular Engineering. 18:87-94
Functional antibodies produced in tobacco plants were first reported over a decade ago (1989). The basic protocol used to generate these ‘plantibodies’ involved the independent cloning of H and L chain antibody genes in Agrobacterium tumefaciens
Publikováno v:
Plant Biotechnology and Transgenic Plants
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::813dab2546c943c396a93906266f6d2c
https://doi.org/10.1201/9780203910849.ch17
https://doi.org/10.1201/9780203910849.ch17
Publikováno v:
Plants as Factories for Protein Production ISBN: 9789048161133
Genetically engineered agricultural plants with improved traits (e.g. herbicide and pest resistance) have yielded significant agricultural revenues over the past 5 years. In addition, numerous immunotherapeutic proteins, antibodies and vaccines have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3a8f89aaab55c0684c59504606df0f3
https://doi.org/10.1007/978-94-017-2693-1_4
https://doi.org/10.1007/978-94-017-2693-1_4
Autor:
Keith L. Wycoff, Mich B. Hein, Thomas Lehner, Ban Y. Hikmat, Nicholas D. Vine, Lloyd Yu, Julian K.-C. Ma, Daniel Chargelegue
Publikováno v:
Nature medicine. 4(5)
A functional comparison was made between a monoclonal secretory antibody generated in transgenic plants and its parent murine IgC antibody .The affinity constants of both antibodies for a Streptococcus mutans adhesion protein were similar. However th