Zobrazeno 1 - 10
of 185
pro vyhledávání: '"Lloyd S. Miller"'
Autor:
Michael Battaglia, Alex C. Sunshine, Wei Luo, Richard Jin, Alifa Stith, Matt Lindemann, Lloyd S. Miller, Satrajit Sinha, Elizabeth Wohlfert, Lee Ann Garrett-Sinha
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionEts1 is a lymphoid-enriched transcription factor that regulates B- and Tcell functions in development and disease. Mice that lack Ets1 (Ets1 KO) develop spontaneous autoimmune disease with high levels of autoantibodies. Naïve CD4 + T cel
Externí odkaz:
https://doaj.org/article/b59a18aefa3f4975951efa03b14bb17b
Autor:
John M. Thompson, Alyssa G. Ashbaugh, Yu Wang, Robert J. Miller, Julie E. Pickett, Daniel L. J. Thorek, Robert S. Sterling, Lloyd S. Miller
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 16, Iss 1, Pp 1-11 (2021)
Abstract Background The pathogenesis of hematogenous orthopaedic implant-associated infections (HOIAI) remains largely unknown, with little understanding of the influence of the physis on bacterial seeding. Since the growth velocity in the physis of
Externí odkaz:
https://doaj.org/article/95d3da6cdde44a25a5794ddbd2d6e19a
Autor:
Oren Gordon, Dustin A. Dikeman, Roger V. Ortines, Yu Wang, Christine Youn, Mohammed Mumtaz, Nicholas Orlando, Jeffrey Zhang, Aman M. Patel, Ethan Gough, Amit Kaushik, Eric L. Nuermberger, Anna M. Upton, Nader Fotouhi, Lloyd S. Miller, Nathan K. Archer
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 5 (2022)
ABSTRACT Staphylococcus aureus is an important cause of various infections in humans, including bacteremia, skin and soft tissue infections, and infections associated with implanted medical devices. The emergence of hospital- and community-acquired m
Externí odkaz:
https://doaj.org/article/d6e58e0732d248c5ad23795e60ded5ae
Autor:
Adela S. Oliva Chávez, Xiaowei Wang, Liron Marnin, Nathan K. Archer, Holly L. Hammond, Erin E. McClure Carroll, Dana K. Shaw, Brenden G. Tully, Amanda D. Buskirk, Shelby L. Ford, L. Rainer Butler, Preeti Shahi, Kateryna Morozova, Cristina C. Clement, Lauren Lawres, Anya J. O’ Neal, Choukri Ben Mamoun, Kathleen L. Mason, Brandi E. Hobbs, Glen A. Scoles, Eileen M. Barry, Daniel E. Sonenshine, Utpal Pal, Jesus G. Valenzuela, Marcelo B. Sztein, Marcela F. Pasetti, Michael L. Levin, Michail Kotsyfakis, Steven M. Jay, Jason F. Huntley, Lloyd S. Miller, Laura Santambrogio, Joao H. F. Pedra
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Extracellular vesicles have been implicated in the transmission of pathogens from the arthropod to the human host. Here the authors show that tick-derived extracellular vesicles play a role in feeding and modulate the outcome of bacterial infection.
Externí odkaz:
https://doaj.org/article/41e1c07d29b74e5f972379e9fa87802a
Autor:
Pranay R. Randad, Jesper Larsen, Hülya Kaya, Nora Pisanic, Carly Ordak, Lance B. Price, Maliha Aziz, Maya L. Nadimpalli, Sarah Rhodes, Jill R. Stewart, Dave C. Love, David Mohr, Meghan F. Davis, Lloyd S. Miller, Devon Hall, Karen C. Carroll, Trish M. Perl, Christopher D. Heaney
Publikováno v:
Emerging Infectious Diseases, Vol 27, Iss 3, Pp 740-748 (2021)
Transmission of livestock-associated Staphylococcus aureus clonal complex 9 (LA-SA CC9) between pigs raised on industrial hog operations (IHOs) and humans in the United States is poorly understood. We analyzed whole-genome sequences from 32 internati
Externí odkaz:
https://doaj.org/article/218d9c88e116407a85ebed356fe7cb3b
Autor:
Howard Y. Park, Stephen D. Zoller, Vishal Hegde, William Sheppard, Zachary Burke, Gideon Blumstein, Christopher Hamad, Marina Sprague, John Hoang, Ryan Smith, Francisco Romero Pastrana, Julie Czupryna, Lloyd S. Miller, Marina López-Álvarez, Mafalda Bispo, Marleen van Oosten, Jan Maarten van Dijl, Kevin P. Francis, Nicholas M. Bernthal
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Implant-associated infections are challenging to diagnose and treat. Fluorescent probes have been heralded as a technologic advancement that can improve our ability to non-invasively identify infecting organisms, as well as guide the inexact
Externí odkaz:
https://doaj.org/article/86227a18cd1245e9a49adb1de27d0f16
Autor:
Franziska Herster, Zsofia Bittner, Nathan K. Archer, Sabine Dickhöfer, David Eisel, Tatjana Eigenbrod, Thomas Knorpp, Nicole Schneiderhan-Marra, Markus W. Löffler, Hubert Kalbacher, Tim Vierbuchen, Holger Heine, Lloyd S. Miller, Dominik Hartl, Lukas Freund, Knut Schäkel, Martin Heister, Kamran Ghoreschi, Alexander N. R. Weber
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Antimicrobial peptide LL37 can bind nucleic acids and potentiate their sensing by endosomal TLRs. Here the authors show that LL37 binds to RNA from neutrophil extracellular traps (NETs), which amplifies inflammation and production of more LL37 and NE
Externí odkaz:
https://doaj.org/article/ea97f7082ce74177a2af8db079fd79c4
Autor:
Alvaro A. Ordonez, Matthew F.L. Parker, Robert J. Miller, Donika Plyku, Camilo A. Ruiz-Bedoya, Elizabeth W. Tucker, Justin M. Luu, Dustin A. Dikeman, Wojciech G. Lesniak, Daniel P. Holt, Robert F. Dannals, Lloyd S. Miller, Steven P. Rowe, David M. Wilson, Sanjay K. Jain
Publikováno v:
JCI Insight, Vol 7, Iss 1 (2022)
Tools for noninvasive detection of bacterial pathogens are needed but are not currently available for clinical use. We have previously shown that para-aminobenzoic acid (PABA) rapidly accumulates in a wide range of pathogenic bacteria, motivating the
Externí odkaz:
https://doaj.org/article/5177739448e9442882f49a5d260f8ffe
Autor:
Juan-Manuel Leyva-Castillo, Mrinmoy Das, Jennifer Kane, Maria Strakosha, Sonal Singh, Daniel Sen Hoi Wong, Alexander R. Horswill, Hajime Karasuyama, Frank Brombacher, Lloyd S. Miller, Raif S. Geha
Publikováno v:
JCI Insight, Vol 6, Iss 21 (2021)
Superficial cutaneous Staphylococcus aureus (S. aureus) infection in humans can lead to soft tissue infection, an important cause of morbidity and mortality. IL-17A production by skin TCRγδ+ cells in response to IL-1 and IL-23 produced by epithelia
Externí odkaz:
https://doaj.org/article/f92c5bebf6394434bab77102e9cc1d06
Autor:
Dongwon Kim, Ruosi Chen, Mary Sheu, Noori Kim, Sooah Kim, Nasif Islam, Eric M. Wier, Gaofeng Wang, Ang Li, Angela Park, Wooyang Son, Benjamin Evans, Victoria Yu, Vicky P. Prizmic, Eugene Oh, Zixiao Wang, Jianshi Yu, Weiliang Huang, Nathan K. Archer, Zhiqi Hu, Nashay Clemetson, Amanda M. Nelson, Anna Chien, Ginette A. Okoye, Lloyd S. Miller, Gabriel Ghiaur, Sewon Kang, Jace W. Jones, Maureen A. Kane, Luis A. Garza
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
During wound induced hair follicle neogenesis (WIHN), stem cells regenerate hair follicles but how this arises is unclear. Here, the authors show that self-noncoding dsRNA activates the antiviral receptor TLR3 to induce intrinsic retinoic acid, which
Externí odkaz:
https://doaj.org/article/564f599801064b9c89f41e9691fc9196