Výsledky vyhledávání - "Lloyd M. L. Smyth"

Akademický článek

Dose-escalated radiotherapy to 82 Gy for prostate cancer following insertion of a peri-rectal hydrogel spacer: 3-year outcomes from a phase II trial

Autor: Andrew W. See, Patrick Bowden, Geoffrey Wells, Sree Appu, Nathan Lawrentschuk, Peter Liodakis, Chloe Pandeli, Yolanda Aarons, Lloyd M. L. Smyth, Dean P. McKenzie

Publikováno v: Radiation Oncology, Vol 17, Iss 1, Pp 1-10 (2022)

Abstract Background Dose-escalation to above 80 Gy during external beam radiotherapy for localised prostate cancer leads to improved oncological outcomes but also substantially increased rectal toxicity. The aim of this study was to demonstrate the s

Externí odkaz: https://doaj.org/article/e673c3a3b4f2460bae153c915b2c8584

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Akademický článek

Dose reduction to organs at risk with deep-inspiration breath-hold during right breast radiotherapy: a treatment planning study

Autor: Chloe Pandeli, Lloyd M. L. Smyth, Steven David, Andrew W. See

Publikováno v: Radiation Oncology, Vol 14, Iss 1, Pp 1-10 (2019)

Abstract Background The addition of regional nodal radiation (RNI) to whole breast irradiation for high risk breast cancer improves metastases free survival and new data suggests it contributes additional benefit to overall survival. Deep inspiration

Externí odkaz: https://doaj.org/article/ec754b0b8b344f18a750c91380338e7e

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Synchrotron Microbeam Radiation Therapy for the Treatment of Lung Carcinoma: A Preclinical Study

Autor: Verdiana Trappetti, Jean A. Laissue, Nahoko Shintani, Lloyd M. L. Smyth, David Haberthür, Cristian Fernandez-Palomo, Valentin Djonov, Duncan Butler, Micah Barnes, Michael John de Veer, Marie C. Vozenin, Mitzi Klein

Publikováno v: Trappetti, Verdiana; Fernandez Palomo, Cristian; Smyth, Lloyd; Klein, Mitzi; Haberthür, David; Butler, Duncan; Barnes, Micah; Shintani, Nahoko; de Veer, Michael; Laissue, Jean A.; Vozenin, Marie C.; Djonov, Valentin (2021). Synchrotron Microbeam Radiotherapy for the treatment of lung carcinoma: a pre-clinical study. International journal of radiation oncology, biology, physics, 111(5), pp. 1276-1288. Elsevier 10.1016/j.ijrobp.2021.07.1717

Purpose In the last three decades, Synchrotron Microbeam Radiation Therapy (S-MRT) has been shown to achieve both good tumour control and normal tissue sparing in a range of pre-clinical animal models. However, the use of S-MRT for the treatment of l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b8d0451ff8464e4cbb11595bc252cab
https://doi.org/10.1016/j.ijrobp.2021.07.1717

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Focal low dose-rate brachytherapy for low to intermediate risk prostate cancer: preliminary experience at an Australian institution

Autor: Elliot Anderson, Nathan Lawrentschuk, Lloyd M. L. Smyth, Jeremy Grummet, Richard O'Sullivan, Andrew Ryan, Andrew W. See

Publikováno v: Transl Androl Urol

BACKGROUND: Focal treatment for prostate cancer (PCa) is a hybrid approach combining ablative treatment of the involved prostate gland and continued active surveillance (AS) of the unaffected gland. Low dose-rate (LDR) brachytherapy can be used as a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e5a3955933d8a4316098c62a27cbaa5
https://doi.org/10.21037/tau-21-508

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68Ga-PSMA-PET screening and transponder-guided salvage radiotherapy to the prostate bed alone for biochemical recurrence following prostatectomy: interim outcomes of a phase II trial

Publikováno v: World Journal of Urology

Purpose To evaluate outcomes for men with biochemically recurrent prostate cancer who were selected for transponder-guided salvage radiotherapy (SRT) to the prostate bed alone by 68Ga-labelled prostate-specific membrane antigen positron emission tomo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca406faddea9e425b7955d5c8966c60f
http://europepmc.org/articles/PMC8571130

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The γH2AX DSB marker may not be a suitable biodosimeter to measure the biological MRT valley dose

Autor: Lloyd M. L. Smyth, Cameron J. Nowell, Leonie Cann, Liam R. J. Day, Peter Rogers, Jacqueline F. Donoghue, Helen B. Forrester, Jeffrey C. Crosbie, Jessica Ventura

Publikováno v: International Journal of Radiation Biology. 97:642-656

γH2AX biodosimetry has been proposed as an alternative dosimetry method for microbeam radiation therapy (MRT) because conventional dosimeters, such as ionization chambers, lack the spatial resolution required to accurately measure the MRT valley dos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e2db1043b5cf03e504c4f12cca358e8
https://doi.org/10.1080/09553002.2021.1893854

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Identifying optimal clinical scenarios for synchrotron microbeam radiation therapy: A treatment planning study

Autor: Liam R. J. Day, Sashendra Senthi, Jeffrey C. Crosbie, Lloyd M. L. Smyth, Peter Rogers, Katrina Woodford

Publikováno v: Physica Medica. 60:111-119

Purpose: Synchrotron Microbeam Radiation Therapy (MRT) is a pre-clinical modality characterised by spatial dose fractionation on a microscopic scale. Treatment planning studies using clinical datasets have not yet been conducted. Our aim was to inves

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d45805290d2f7a11ace0017f66486ca
https://doi.org/10.1016/j.ejmp.2019.03.019

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A commercial treatment planning system with a hybrid dose calculation algorithm for synchrotron radiotherapy trials

Autor: Paolo Pellicioli, Lloyd M. L. Smyth, Liam R. J. Day, Jeffrey C. Crosbie, Mattia Donzelli, Stefan Bartzsch, Micah Barnes

Publikováno v: Physics in medicine and biology. 66(5)

Synchrotron Radiotherapy (SyncRT) is a preclinical radiation treatment which delivers synchrotron x-rays to cancer targets. SyncRT allows for novel treatments such as Microbeam Radiotherapy, which has been shown to have exceptional healthy tissue spa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc627462c77e55b787fa35d9c405d7dd
https://pubmed.ncbi.nlm.nih.gov/33373979

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Erratum: Fernandez-Palomo, C., et al. Animal Models in Microbeam Radiation Therapy: A Scoping Review. Cancers 2020, 12, 527

Autor: Heidrun Janka, Lloyd M. L. Smyth, Jennifer Fazzari, Verdiana Trappetti, Cristian Fernandez-Palomo, Jean A. Laissue, Valentin Djonov

Publikováno v: Cancers, Vol 12, Iss 3174, p 3174 (2020)
Fernandez-Palomo, Cristian; Fazzari, Jennifer Michelina; Trappetti, Verdiana; Smyth, Lloyd; Janka, Heidrun Ilonka; Laissue, Jean; Djonov, Valentin (2020). Erratum: Fernandez-Palomo, C., et al. Animal Models in Microbeam Radiation Therapy: A Scoping Review. Cancers 2020, 12, 527. Cancers, 12(11), p. 3174. MDPI AG 10.3390/cancers12113174

The authors wish to make the following corrections to this paper [...]

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62f186fd16811ecbf00cd527e5e7dce3
https://www.mdpi.com/2072-6694/12/11/3174

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