Zobrazeno 1 - 10
of 6 010
pro vyhledávání: '"Lloyd G"'
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 18, Iss 1, Pp 1-10 (2023)
Abstract Background Estimating the contribution of endplate oedema known as Modic changes to lower back pain (LBP) has been the subject of multiple observational studies and reviews, some of which conclude that the evidence for an association of Modi
Externí odkaz:
https://doaj.org/article/f062a8fd37944ddb9a5fec6b8da18185
Autor:
Dennis G. Moledina, Wassim Obeid, Rex N. Smith, Ivy Rosales, Meghan E. Sise, Gilbert Moeckel, Michael Kashgarian, Michael Kuperman, Kirk N. Campbell, Sean Lefferts, Kristin Meliambro, Markus Bitzer, Mark A. Perazella, Randy L. Luciano, Jordan S. Pober, Lloyd G. Cantley, Robert B. Colvin, F. Perry Wilson, Chirag R. Parikh
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 13 (2023)
Background Acute tubulointerstitial nephritis (AIN) is one of the few causes of acute kidney injury with diagnosis-specific treatment options. However, due to the need to obtain a kidney biopsy for histological confirmation, AIN diagnosis can be dela
Externí odkaz:
https://doaj.org/article/8efe2f2685704f25a2ece87934b2792f
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Acute kidney injury can lead to chronic kidney disease. Here the authors show that the transition is related to a macrophage-mediated second wave of inflammatory cells that promote late tubule injury, dedifferentiation and fibrosis. Suppressing this
Externí odkaz:
https://doaj.org/article/748a4ec9647d452c9842c256487259ac
Autor:
Yumeng Wen, Leyuan Xu, Isabel Melchinger, Heather Thiessen-Philbrook, Dennis G. Moledina, Steven G. Coca, Chi-yuan Hsu, Alan S. Go, Kathleen D. Liu, Edward D. Siew, T. Alp Ikizler, Vernon M. Chinchilli, James S. Kaufman, Paul L. Kimmel, Jonathan Himmelfarb, Lloyd G. Cantley, Chirag R. Parikh, the ASSESS-AKI Consortium
Publikováno v:
JCI Insight, Vol 8, Iss 9 (2023)
BACKGROUND Longitudinal investigations of murine acute kidney injury (AKI) suggest that injury and inflammation may persist long after the initial insult. However, the evolution of these processes and their prognostic values are unknown in patients w
Externí odkaz:
https://doaj.org/article/37f50187e44c4d6ea38694be2b5b38c5
Autor:
Mary Patricia Nowalk, Theresa M. Sax, Michael Susick, Louise H. Taylor, Lloyd G. Clarke, Klancie Dauer, Karen Clarke, Krissy Moehling Geffel, Richard K. Zimmerman, G.K. Balasubramani
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 28, Iss , Pp 100596- (2023)
Background: Little is known about the effects of a mild SARS-CoV-2 infection on health-related quality of life. Methods: This prospective observational study of symptomatic adults (18–87 years) who sought outpatient care for an acute respiratory il
Externí odkaz:
https://doaj.org/article/96d7ac1210d74e9e8256cd98578eec90
Autor:
Richard K. Zimmerman, Mary Patricia Nowalk, Todd Bear, Rachel Taber, Karen S. Clarke, Theresa M. Sax, Heather Eng, Lloyd G. Clarke, G. K. Balasubramani
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 17, Iss 4, Pp 1109-1112 (2021)
The introduction and rapid transmission of SARS-CoV-2 in the United States resulted in methods to assess, mitigate, and contain the resulting COVID-19 disease derived from limited knowledge. Screening for testing has been based on symptoms typically
Externí odkaz:
https://doaj.org/article/2d1db3cb7f014746bb15dbc7914f1bc1
Autor:
Yu Yamamoto, Nazli Dizman, F Perry Wilson, Dennis G Moledina, Chirag R Parikh, Michael Simonov, Navid Hafez, Megan L Baker, Mark A Perazella, Anushree C Shirali, Jason Weinstein, Jeffrey M Testani, Lloyd G Cantley
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 3 (2022)
Background In patients receiving immune checkpoint inhibitor (ICI) therapy, acute kidney injury (AKI) is common, and can occur either from kidney injury unrelated to ICI use or from immune activation resulting in acute interstitial nephritis (AIN). I
Externí odkaz:
https://doaj.org/article/8f30c21e89be4bcfb73a578dcc6bbadb
Autor:
Harith A. Alataby, Lloyd G. Muzangwa, Muhamed K. Atere, Joseph Bibawy, Keith T. Diaz, Jay M. Nfonoyim
Publikováno v:
Journal of Community Hospital Internal Medicine Perspectives, Vol 10, Iss 5, Pp 452-455 (2020)
We describe the successful medical management of an infected aorto-bi-Iliac endograft. In this case report, we provide an example of a patient with an infected aorto-bi-iliac endograft and how appropriate medical management may result in a positive o
Externí odkaz:
https://doaj.org/article/709a91f5d46a430b952599622ff8794f
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
In the evolving landscape of highly multiplexed imaging techniques that can be applied to study complex cellular microenvironments, this review characterizes the use of imaging mass cytometry (IMC) to study the human kidney. We provide technical deta
Externí odkaz:
https://doaj.org/article/be0e3fa9115a4000be68e0187a1313d4
Autor:
Khadija Banu, Qisheng Lin, John M. Basgen, Marina Planoutene, Chengguo Wei, Anand C. Reghuvaran, Xuefei Tian, Hongmei Shi, Felipe Garzon, Aitor Garzia, Nicholas Chun, Arun Cumpelik, Andrew D. Santeusanio, Weijia Zhang, Bhaskar Das, Fadi Salem, Li Li, Shuta Ishibe, Lloyd G. Cantley, Lewis Kaufman, Kevin V. Lemley, Zhaohui Ni, John Cijiang He, Barbara Murphy, Madhav C. Menon
Publikováno v:
JCI Insight, Vol 6, Iss 19 (2021)
Herein, we report that Shroom3 knockdown, via Fyn inhibition, induced albuminuria with foot process effacement (FPE) without focal segmental glomerulosclerosis (FSGS) or podocytopenia. Interestingly, knockdown mice had reduced podocyte volumes. Human
Externí odkaz:
https://doaj.org/article/48caabe5bbcf4213b0f25719c459b46d