Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Lloyd Bridge"'
Autor:
John M Ankers, Raheela Awais, Nicholas A Jones, James Boyd, Sheila Ryan, Antony D Adamson, Claire V Harper, Lloyd Bridge, David G Spiller, Dean A Jackson, Pawel Paszek, Violaine Sée, Michael RH White
Publikováno v:
eLife, Vol 5 (2016)
Dynamic cellular systems reprogram gene expression to ensure appropriate cellular fate responses to specific extracellular cues. Here we demonstrate that the dynamics of Nuclear Factor kappa B (NF-κB) signalling and the cell cycle are prioritised di
Externí odkaz:
https://doaj.org/article/c93dc22ec0694d76b838a26b6974d89e
Autor:
Wesley Keur, Dong Guo, Annelien J.M. Zweemer, Henk de Vries, Laura H. Heitman, Lloyd Bridge, Lambertus A. Peletier, Adriaan P. IJzerman
Publikováno v:
British Journal of Pharmacology
Ligand-receptor binding kinetics is receiving increasing attention in the drug research community. The Motulsky and Mahan model, a one-state model, offers a method for measuring the binding kinetics of an unlabelled ligand, with the assumption that t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6cc5167810c40719528c11c609fd7fd1
https://doi.org/10.1111/bph.14184
https://doi.org/10.1111/bph.14184
Autor:
Violaine Sée, Dean A. Jackson, Pawel Paszek, Nicholas Jones, Claire V. Harper, Lloyd Bridge, Sheila Ryan, John M. Ankers, Michael R. H. White, Antony Adamson, David G. Spiller, Raheela Awais, James Boyd
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e742f91bdfe0bb42bd91067221aec9e0
https://doi.org/10.7554/elife.10473.038
https://doi.org/10.7554/elife.10473.038
Autor:
Antony Adamson, Claire V. Harper, James Boyd, Lloyd Bridge, Raheela Awais, Michael R. H. White, Violaine Sée, Pawel Paszek, Sheila Ryan, John M. Ankers, Dean A. Jackson, David G. Spiller, Nicholas Jones
Publikováno v:
eLife, Vol 5 (2016)
Ankers, J M, Awais, R, Jones, N A, Boyd, J, Ryan, S, Adamson, A D, Harper, C V, Bridge, L, Spiller, D G, Jackson, D A, Paszek, P, Sée, V & White, M R 2016, ' Dynamic NF-κB and E2F interactions control the priority and timing of inflammatory signalling and cell proliferation ', eLife, vol. 5, e10473 . https://doi.org/10.7554/eLife.10473
eLife
Ankers, J M, Awais, R, Jones, N A, Boyd, J, Ryan, S, Adamson, A D, Harper, C V, Bridge, L, Spiller, D G, Jackson, D A, Paszek, P, Sée, V & White, M R 2016, ' Dynamic NF-κB and E2F interactions control the priority and timing of inflammatory signalling and cell proliferation ', eLife, vol. 5, e10473 . https://doi.org/10.7554/eLife.10473
eLife
Dynamic cellular systems reprogram gene expression to ensure appropriate cellular fate responses to specific extracellular cues. Here we demonstrate that the dynamics of Nuclear Factor kappa B (NF-κB) signalling and the cell cycle are prioritised di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b7b969879e031227b4d5b75f3926bab
https://cronfa.swan.ac.uk/Record/cronfa28253/Download/0028253-5262016123753PM.pdf
https://cronfa.swan.ac.uk/Record/cronfa28253/Download/0028253-5262016123753PM.pdf
Publikováno v:
Mathematical Biosciences. 235:32-44
New models of gene transcriptional responses to auxin signalling in Arabidopsis are presented. This work extends a previous model of auxin signalling to include networks of gene-sets which may control developmental responses along auxin gradients. Ke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71acdc494137c18e726e2cda3dda0ff0
https://doi.org/10.1016/j.mbs.2011.10.005
https://doi.org/10.1016/j.mbs.2011.10.005
The relationship between components of biochemical network and the resulting dynamics of the overall system is a key focus of computational biology. However, as these networks and resulting mathematical models are inherently complex and non-linear, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35d1d6ce752756b186a1191ac5c562f8
https://cronfa.swan.ac.uk/Record/cronfa28313
https://cronfa.swan.ac.uk/Record/cronfa28313
Publikováno v:
Journal of Engineering Mathematics. 45:247-268
The one-dimensional steady-state heat and mass transfer in a two-phase zone of a water-saturated porous medium is studied. The system consists of a sand-water-vapour mixture in a tube that is heated from above and cooled from below. Under certain con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e43d8cf3bfbb9c20dda6ff9e93ebf378
https://doi.org/10.1023/a:1022690802938
https://doi.org/10.1023/a:1022690802938
Publikováno v:
Scopus-Elsevier
Plants display a range of striking architectural adaptations when grown at elevated temperatures. In the model plant Arabidopsis thaliana , these include elongation of petioles, and increased petiole and leaf angles from the soil surface. The potenti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d8661b6b3edbd6dabb064aca20a02c0
https://cronfa.swan.ac.uk/Record/cronfa15752
https://cronfa.swan.ac.uk/Record/cronfa15752
Autor:
Lloyd Bridge
With the recent discovery and increased recognition of constitutive activity of G-protein coupled receptors (GPCRs) and inverse agonists have come a number of important questions. The signaling mechanisms underlying inverse agonist effects on constit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22541bb4c43e357db751ea6fc5d34daa
https://cronfa.swan.ac.uk/Record/cronfa16573
https://cronfa.swan.ac.uk/Record/cronfa16573
A new mathematical model of cell signalling for a two-ligand G-protein coupled receptor (GPCR) system is presented. This model extends the single-ligand cubic ternary complex to account for the possibility of an agonist and an antagonist competing fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98c3596af1c16c83f52a64ee06359edd
https://cronfa.swan.ac.uk/Record/cronfa16572
https://cronfa.swan.ac.uk/Record/cronfa16572