Plasma total prion protein as a potential biomarker for neurodegenerative dementia: diagnostic accuracy in the spectrum of prion diseases.

Autor: Llorens, F.^1,2,3 (AUTHOR) franc.llorens@gmail.com, Villar‐Piqué, A.³ (AUTHOR) annavillarpique@gmail.com, Schmitz, M.^3,4 (AUTHOR) matthias.schmitz@med.uni, Diaz‐Lucena, D.¹ (AUTHOR), Wohlhage, M.³ (AUTHOR), Hermann, P.³ (AUTHOR), Goebel, S.³ (AUTHOR), Schmidt, I.³ (AUTHOR), Glatzel, M.⁵ (AUTHOR), Hauw, J.‐J.⁶ (AUTHOR), Sikorska, B.⁷ (AUTHOR), Liberski, P. P.⁷ (AUTHOR), Riggert, J.⁸ (AUTHOR), Ferrer, I.^1,2,9 (AUTHOR), Zerr, I.^3,4 (AUTHOR)

Publikováno v: Neuropathology & Applied Neurobiology. Apr2020, Vol. 46 Issue 3, p240-254. 15p.

Analysis of co-isogenic prion protein deficient mice reveals behavioral deficits, learning impairment, and enhanced hippocampal excitability

Autor: Matamoros-Angles, A, Hervera, A, Soriano, J, Martí, E, Carulla, P, Llorens, F, Nuvolone, M, Aguzzi, Adriano, Ferrer, I, Gruart, A, Delgado-García, J M, Del Río, J A

Publikováno v: BMC Biology, Vol 20, Iss 1, Pp 1-25 (2022)
Dipòsit Digital de la UB
Universidad de Barcelona
BMC Biology

Background: Cellular prion protein (PrPC) is a cell surface GPI-anchored protein, usually known for its role in the pathogenesis of human and animal prionopathies. However, increasing knowledge about the participation of PrPC in prion pathogenesis co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a4f815e2b8d87e6a8f4f51818bfd064
https://www.zora.uzh.ch/id/eprint/219066/

Additional file 6 of Analysis of co-isogenic prion protein deficient mice reveals behavioral deficits, learning impairment, and enhanced hippocampal excitability

Autor: Matamoros-Angles, A., Hervera, A., Soriano, J., Mart��, E., Carulla, P., Llorens, F., Nuvolone, M., Aguzzi, A., Ferrer, I., Gruart, A., Delgado-Garc��a, J. M., Del R��o, J. A.

Additional file 6: Table S2. List of the protein-coding significantly upregulated genes in PrnpZH3/ZH3 hippocampus compared to Prnp+/+.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4370d559bea9864f7665fa232f236330

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TREM2 expression in the brain and biological fluids in prion diseases.

Autor: Diaz-Lucena D; Network Center for Biomedical Research in Neurodegenerative Diseases (CIBERNED), L'Hospitalet de Llobregat, Spain.; Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Spain., Kruse N; University Medical Center Göttingen, Institute of Neuropathology, Göttingen, Germany., Thüne K; Department of Neurology, University Medical Center Göttingen, Gern August University, Robert Koch Strasse 40, 37075, Göttingen, Germany., Schmitz M; Department of Neurology, University Medical Center Göttingen, Gern August University, Robert Koch Strasse 40, 37075, Göttingen, Germany.; German Center for Neurodegenerative Diseases (DZNE), Göttingen, Germany., Villar-Piqué A; Network Center for Biomedical Research in Neurodegenerative Diseases (CIBERNED), L'Hospitalet de Llobregat, Spain.; Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Spain., da Cunha JEG; Keizo Asami Laboratory (LIKA), Universidade Federal de Pernambuco (UFPE), Recife, Brazil., Hermann P; Department of Neurology, University Medical Center Göttingen, Gern August University, Robert Koch Strasse 40, 37075, Göttingen, Germany., López-Pérez Ó; Network Center for Biomedical Research in Neurodegenerative Diseases (CIBERNED), L'Hospitalet de Llobregat, Spain.; Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Spain., Andrés-Benito P; Network Center for Biomedical Research in Neurodegenerative Diseases (CIBERNED), L'Hospitalet de Llobregat, Spain.; Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Spain., Ladogana A; Department of Neurosciences, Istituto Superiore Di Sanità, Rome, Italy., Calero M; Alzheimer Disease Research Unit, CIEN Foundation, Chronic Disease Programme, Queen Sofia Foundation Alzheimer Center, Instituto de Salud Carlos III, Madrid, Spain.; Network Center for Biomedical Research in Neurodegenerative Diseases (CIBERNED), Madrid, Spain., Vidal E; Centre de Recerca en Sanitat Animal, Campus Universitat Autònoma de Barcelona, Institut de Recerca I Tecnologia Agroalimentàries, Bellaterra, Spain., Riggert J; Department of Transfusion Medicine, University Medical School, Göttingen, Germany., Pineau H; Department of Medicine-Division of Neurology, Centre for Prions and Protein Folding Diseases, University of Alberta, Edmonton, Canada., Sim V; Department of Medicine-Division of Neurology, Centre for Prions and Protein Folding Diseases, University of Alberta, Edmonton, Canada., Zetterberg H; Department of Psychiatry and Neurochemistry, The Sahlgrenska Academy at the University of Gothenburg, Institute of Neuroscience and Physiology, Mölndal, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.; Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK.; UK Dementia Research Institute, London, UK., Blennow K; Department of Psychiatry and Neurochemistry, The Sahlgrenska Academy at the University of Gothenburg, Institute of Neuroscience and Physiology, Mölndal, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden., Del Río JA; Molecular and Cellular Neurobiotechnology, Scientific Park of Barcelona, Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute for Science and Technology (BIST), Barcelona, Spain.; Department of Cell Biology, Physiology and Immunology, Faculty of Biology, University of Barcelona, Barcelona, Spain.; Network Center for Biomedical Research in Neurodegenerative Diseases (CIBERNED), Barcelona, Spain.; University of Barcelona, Institute of Neuroscience, Barcelona, Spain., Marín-Moreno A; Centro de Investigación en Sanidad Animal, CISA-INIA, Madrid, Spain., Espinosa JC; Centro de Investigación en Sanidad Animal, CISA-INIA, Madrid, Spain., Torres JM; Centro de Investigación en Sanidad Animal, CISA-INIA, Madrid, Spain., Sánchez-Valle R; Alzheimer's Disease and Other Cognitive Disorders Unit, Neurology Department, Hospital Clinic de Barcelona, Institut D'Investigacions Biomediques August Pi I Sunyer (IDIBAPS), Barcelona, Spain., Mollenhauer B; Paracelsus-Elena Klinik, Kassel, Germany.; Department of Neurology, University Medical Centre Göttingen, Göttingen, Germany., Ferrer I; Network Center for Biomedical Research in Neurodegenerative Diseases (CIBERNED), L'Hospitalet de Llobregat, Spain. 80982ifa@gmail.com.; Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Spain. 80982ifa@gmail.com.; Department of Pathology and Experimental Therapeutics, Hospitalet de Llobregat, University of Barcelona, Feixa Llarga S/N, 08907, Barcelona, Spain. 80982ifa@gmail.com., Zerr I; Department of Neurology, University Medical Center Göttingen, Gern August University, Robert Koch Strasse 40, 37075, Göttingen, Germany. ingazerr@med.uni-goettingen.de.; German Center for Neurodegenerative Diseases (DZNE), Göttingen, Germany. ingazerr@med.uni-goettingen.de., Llorens F; Network Center for Biomedical Research in Neurodegenerative Diseases (CIBERNED), L'Hospitalet de Llobregat, Spain.; Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Spain.; Department of Neurology, University Medical Center Göttingen, Gern August University, Robert Koch Strasse 40, 37075, Göttingen, Germany.

Publikováno v: Acta neuropathologica [Acta Neuropathol] 2021 Jun; Vol. 141 (6), pp. 841-859. Date of Electronic Publication: 2021 Apr 21.