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The product structure of MPS-under-permutations

Autor: Florido-Llinàs, Marta, Alhambra, Álvaro M., Trivedi, Rahul, Schuch, Norbert, Pérez-García, David, Cirac, J. Ignacio

Tensor network methods have proved to be highly effective in addressing a wide variety of physical scenarios, including those lacking an intrinsic one-dimensional geometry. In such contexts, it is possible for the problem to exhibit a weak form of pe

Externí odkaz: http://arxiv.org/abs/2410.19541

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Regular language quantum states

Autor: Florido-Llinàs, Marta, Alhambra, Álvaro M., Pérez-García, David, Cirac, J. Ignacio

We introduce regular language states, a family of quantum many-body states. They are built from a special class of formal languages, called regular, which has been thoroughly studied in the field of computer science. They can be understood as the sup

Externí odkaz: http://arxiv.org/abs/2407.17641

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Akademický článek

A Plasmodium falciparum MORC protein complex modulates epigenetic control of gene expression through interaction with heterochromatin

Autor: Maneesh Kumar Singh, Victoria Ann Bonnell, Israel Tojal Da Silva, Verônica Feijoli Santiago, Miriam Santos Moraes, Jack Adderley, Christian Doerig, Giuseppe Palmisano, Manuel Llinas, Celia RS Garcia

Publikováno v: eLife, Vol 12 (2024)

Dynamic control of gene expression is critical for blood stage development of malaria parasites. Here, we used multi-omic analyses to investigate transcriptional regulation by the chromatin-associated microrchidia protein, MORC, during asexual blood

Externí odkaz: https://doaj.org/article/f5df1ad565394812b04042a8e700d0d6

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Akademický článek

Homodimerization of CB2 cannabinoid receptor triggered by a bivalent ligand enhances cellular signaling

Autor: Gemma Navarro, Marc Gómez-Autet, Paula Morales, Joan Biel Rebassa, Claudia Llinas del Torrent, Nadine Jagerovic, Leonardo Pardo, Rafael Franco

Publikováno v: Pharmacological Research, Vol 208, Iss , Pp 107363- (2024)

G protein-coupled receptors (GPCRs) exist within a landscape of interconvertible conformational states and in dynamic equilibrium between monomers and higher-order oligomers, both influenced by ligand binding. Here, we show that a homobivalent ligand

Externí odkaz: https://doaj.org/article/0e0661cb783749e1bee2b5a8648b5e8e

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Akademický článek

Anabolic deficits and divergent unfolded protein response underlie skeletal and cardiac muscle growth impairments in the Yoshida hepatoma tumor model of cancer cachexia

Autor: Daniel J. Belcher, Nina Kim, Blanca Navarro‐Llinas, Maria Möller, Francisco J. López‐Soriano, Silvia Busquets, Gustavo A. Nader

Publikováno v: Physiological Reports, Vol 12, Iss 18, Pp n/a-n/a (2024)

Abstract Cancer cachexia manifests as whole body wasting, however, the precise mechanisms governing the alterations in skeletal muscle and cardiac anabolism have yet to be fully elucidated. In this study, we explored changes in anabolic processes in

Externí odkaz: https://doaj.org/article/39e5f67f15304cf6b078dfaea623aa7b

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Akademický článek

Prolonged Venous Transit Is Associated With Lower Likelihood of Favorable Clinical Recovery in Reperfused Anterior Circulation Large‐Vessel Occlusion Stroke

Publikováno v: Stroke: Vascular and Interventional Neurology, Vol 4, Iss 5 (2024)

Background Unfavorable clinical outcomes in patients with acute ischemic stroke caused by large‐vessel occlusions despite successful reperfusion have been associated with poor venous outflow. The objective of this study is to assess the relationshi

Externí odkaz: https://doaj.org/article/b0b7bcb3c8cf4c309d356cf1560830dc

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