Zobrazeno 1 - 10
of 245
pro vyhledávání: '"Llewelyn Roderick"'
Autor:
Robin Duelen, Guillaume Gilbert, Abdulsamie Patel, Nathalie de Schaetzen, Liesbeth De Waele, Llewelyn Roderick, Karin R. Sipido, Catherine M. Verfaillie, Gunnar M. Buyse, Lieven Thorrez, Maurilio Sampaolesi
Publikováno v:
Stem Cells International, Vol 2017 (2017)
The use of human pluripotent stem cells in basic and translational cardiac research requires efficient differentiation protocols towards cardiomyocytes. In vitro differentiation yields heterogeneous populations of ventricular-, atrial-, and nodal-lik
Externí odkaz:
https://doaj.org/article/ec180802ac9541a284ff1e0893a521e1
Autor:
Athiramol Sasi, Andreas Romaine, Pugazendhi Murugan Erusappan, Arne Olav Melleby, Almira Hasic, Christen Peder Dahl, Kaspar Broch, Vibeke Marie Almaas, Rosa Doñate Puertas, H. Llewelyn Roderick, Ida Gjervold Lunde, Ivar Sjaastad, Maria Vistnes, Geir Christensen
Publikováno v:
Matrix Biology Plus, Vol 19, Iss , Pp 100135- (2023)
Cardiac fibrosis is a central pathological feature in several cardiac diseases, but the underlying molecular players are insufficiently understood. The extracellular matrix proteoglycan versican is elevated in heart failure and suggested to be a targ
Externí odkaz:
https://doaj.org/article/e019eb64945b4076a1c582261916bafe
Publikováno v:
Journal of Molecular and Cellular Cardiology Plus, Vol 3, Iss , Pp 100029- (2023)
Externí odkaz:
https://doaj.org/article/3e3b191c4c9e4d30a50d9e3eebaa9d8c
Autor:
Luc Leybaert, Maarten A.J. De Smet, Alessio Lissoni, Rosalie Allewaert, H. Llewelyn Roderick, Geert Bultynck, Mario Delmar, Karin R. Sipido, Katja Witschas
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 6 (2023)
Connexins are crucial cardiac proteins that form hemichannels and gap junctions. Gap junctions are responsible for the propagation of electrical and chemical signals between myocardial cells and cells of the specialized conduction system in order to
Externí odkaz:
https://doaj.org/article/c31bdf27fc3543e5b9392e8b80979d2e
Autor:
Xin Jin, Anna Meletiou, Joshua Chung, Agne Tilunaite, Kateryna Demydenko, Eef Dries, Rosa Doñate Puertas, Matthew Amoni, Ashutosh Tomar, Guillaume Gilbert, Piet Claus, Christian Soeller, Vijay Rajagopal, Karin Sipido, H. Llewelyn Roderick
Publikováno v:
Journal of Molecular and Cellular Cardiology. 179:47-59
Autor:
Matthew Amoni, Eef Dries, Sebastian Ingelaere, Dylan Vermoortele, H. Llewelyn Roderick, Piet Claus, Rik Willems, Karin R. Sipido
Publikováno v:
Cells, Vol 10, Iss 10, p 2629 (2021)
Ischemic heart disease is the most common cause of lethal ventricular arrhythmias and sudden cardiac death (SCD). In patients who are at high risk after myocardial infarction, implantable cardioverter defibrillators are the most effective treatment t
Externí odkaz:
https://doaj.org/article/0f097316d9bc420dac4b8642e6727c44
Autor:
Bjorn Cools, Chandan Kadur Nagaraju, Katrien Vandendriessche, Joeri van Puyvelde, Mohamad Youness, H. Llewelyn Roderick, Marc Gewillig, Karin Sipido, Piet Claus, Filip Rega
Publikováno v:
JACC Basic Transl Sci
In the sheep model with pathophysiologic changes similar to patients with repaired TOF, severe PR leads to fibrotic changes in the RV. Pulmonary valve replacement reverses these fibrotic changes. Early valve replacement led to a quick RV recovery, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::489fea237e4adc6d8fe6ef5d49711c29
https://europepmc.org/articles/PMC10077151/
https://europepmc.org/articles/PMC10077151/
The contraction of cardiac muscle underlying the pumping action of the heart is mediated by the process of excitation-contraction coupling (ECC). While triggered by Ca 2+ entry across the sarcolemma during the action potential, it is the release of C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef5b57ba7849be936ae7f0c1cfe5e7be
https://lirias.kuleuven.be/handle/20.500.12942/704081
https://lirias.kuleuven.be/handle/20.500.12942/704081
Autor:
Xin Jin, Matthew Amoni, Guillaume Gilbert, Eef Dries, Rosa Doñate Puertas, Ashutosh Tomar, Chandan K. Nagaraju, Ankit Pradhan, David I. Yule, Tobie Martens, Roxane Menten, Pieter Vanden Berghe, Filip Rega, Karin Sipido, H. Llewelyn Roderick
Publikováno v:
Basic Research in Cardiology. 117
Autor:
Matthew Smith, Priya Schoenfelder, Maria Manifava, Hannah Polson, Sharon Tooze, H Llewelyn Roderick, Nicholas T. Ktistakis
Ca2+ modulates autophagy at multiple steps including the induction and maturation of autophagosomes, but the magnitude and spatiotemporal properties of this calcium signal and its ultimate effect on the autophagic machinery are unclear. Focusing on t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41159c035ba2a0232b0d534bb879b4f7
https://doi.org/10.1101/2022.11.02.514842
https://doi.org/10.1101/2022.11.02.514842