Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Llewellyn H. Mason"'
Rat mAb have been raised to mouse liver-derived large granular lymphocytes (LGL). One of these mAb (4D11) binds specifically to mouse LGL and appears to recognize a non-allelic determinant on NK-active cell populations. The Ag recognized by 4D11 is e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::799e67219c59bb3677c1e5587446d60b
https://doi.org/10.1159/000416288
https://doi.org/10.1159/000416288
Publikováno v:
The Journal of Immunology. 176:6615-6623
Activating, DAP12-coupled members of the Ly-49 family of NK cell receptors help control viral infections in mice. However, the kinases and/or phosphatases mediating tyrosine phosphorylation of Ly-49D-associated DAP12 have not been elucidated. In this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3eff19e67426e0e65873c0de4c05f86c
https://doi.org/10.4049/jimmunol.176.11.6615
https://doi.org/10.4049/jimmunol.176.11.6615
Autor:
Llewellyn H. Mason
Publikováno v:
Journal of Leukocyte Biology. 68:583-586
Upon ligand recognition, members of the murine Ly-49 receptor family can transmit inhibitory or activating signals that regulate NK cell function. Ly-49A, G, and D have been shown to recognize the murine class I molecule H-2Dd as a potential ligand.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e56dfd96734e3c8cd167c626fd0725db
https://doi.org/10.1189/jlb.68.4.583
https://doi.org/10.1189/jlb.68.4.583
Publikováno v:
The Journal of Immunology. 164:603-611
Murine Ly-49D augments NK cell function upon recognition of target cells expressing H-2Dd. Ly-49D activation is mediated by the immunoreceptor tyrosine-based activation motif-containing signaling moiety Dap-12. In this report we demonstrate that Ly-4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61384030c0a68010c7897dd65bb9f461
https://doi.org/10.4049/jimmunol.164.2.603
https://doi.org/10.4049/jimmunol.164.2.603
Autor:
John R. Ortaldo, Robin Winkler-Pickett, Jami Willette-Brown, Ronald L. Wange, Stephen K. Anderson, Gregory J. Palumbo, Llewellyn H. Mason, Daniel W. McVicar
Publikováno v:
The Journal of Immunology. 163:5269-5277
Murine NK cells express Ly-49 family receptors capable of either inhibiting or activating lytic function. The overlapping patterns of expression of the various receptors have complicated their precise biochemical characterization. Here we describe th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::387618db859582773b108ff1dd19618f
https://doi.org/10.4049/jimmunol.163.10.5269
https://doi.org/10.4049/jimmunol.163.10.5269
Autor:
Andrew P. Makrigiannis, Pierre Gosselin, Llewellyn H. Mason, Lynn S. Taylor, Daniel W. McVicar, John R. Ortaldo, Stephen K. Anderson
Publikováno v:
The Journal of Immunology. 163:4931-4938
The majority of the known Ly49 family members have been isolated from either C57BL/6 (B6) or BALB/c mice. Interestingly, the anti-Ly49 Ab reactivities observed in 129/J mice are different from those of B6 mice. Furthermore, immunoprecipitation of 129
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f4e40ec7b706874d16f3132d7f71622
https://doi.org/10.4049/jimmunol.163.9.4931
https://doi.org/10.4049/jimmunol.163.9.4931
Autor:
William J. Murphy, Robin Winkler-Pickett, Arati Raziuddin, Anna T. Mason, Llewellyn H. Mason, John R. Ortaldo
Publikováno v:
Journal of Leukocyte Biology. 66:512-520
We present data on the strain distribution and functional characteristics of the Ly-49 receptors A, C/I, D, and G2 on DX5+ natural killer (NK) cells. We have examined tyrosine phosphorylation of the Ly-49 molecules, regulation of NK cytotoxic functio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0f9b2205d5e7cb25a703286a6ecb113
https://doi.org/10.1002/jlb.66.3.512
https://doi.org/10.1002/jlb.66.3.512
Autor:
Anthony A. Scalzo, Wayne M. Yokoyama, Hamish R. C. Smith, Azza H. Idris, John R. Ortaldo, Llewellyn H. Mason
Publikováno v:
Proceedings of the National Academy of Sciences. 96:6330-6335
Previously, we established that natural killer (NK) cells from C57BL/6 (B6), but not BALB/c, mice lysed Chinese hamster ovary (CHO) cells, and we mapped the locus that determines this differential CHO-killing capacity to the NK gene complex on chromo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d1a4d9d5931da5e4fc90e5ccb9a80ce
https://doi.org/10.1073/pnas.96.11.6330
https://doi.org/10.1073/pnas.96.11.6330
Publikováno v:
The Journal of Immunology. 162:2035-2043
Members of the murine Ly49 family of receptors have been shown to inhibit and activate NK cell function. Subsets of Ly49-expressing NK cells mediate the rejection of bone marrow cell allografts and the lysis of allogeneic lymphoblasts. In this report
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c78dc70f301892267c9774056c9a0150
https://doi.org/10.4049/jimmunol.162.4.2035
https://doi.org/10.4049/jimmunol.162.4.2035
Autor:
James C. Ryan, William E. Seaman, Eréne C. Niemi, John R. Ortaldo, Llewellyn H. Mason, Mary C. Nakamura, Paul A. Linnemeyer
Publikováno v:
The Journal of Experimental Medicine
The Journal of experimental medicine, vol 189, iss 3
The Journal of experimental medicine, vol 189, iss 3
Although activation of natural killer (NK) cytotoxicity is generally inhibited by target major histocompatibility complex (MHC) class I expression, subtle features of NK allorecognition suggest that NK cells possess receptors that are activated by ta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d41431efa9c3e452b5696477c58d534
http://europepmc.org/articles/PMC2192910
http://europepmc.org/articles/PMC2192910