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pro vyhledávání: '"Lleó A."'
We examine the outcomes of the regular announcements of observing opportunities for ESA's X-ray observatory XMM-Newton issued between 2001 and 2021. We investigate how success rates vary with the lead proposer's gender, academic age and the country w
Externí odkaz:
http://arxiv.org/abs/2402.14075
Autor:
Ochmann, M. W., Kollatschny, W., Probst, M. A., Romero-Colmenero, E., Buckley, D. A. H., Chelouche, D., Chini, R., Grupe, D., Haas, M., Kaspi, S., Komossa, S., Parker, M. L., Santos-Lleo, M., Schartel, N., Famula, P.
Publikováno v:
A&A 686, A17 (2024)
NGC 1566 is known for exhibiting recurrent outbursts, which are accompanied by changes in spectral type. The most recent transient event occurred from 2017 to 2019 and was reported to be accompanied by a change in Seyfert classification from Seyfert
Externí odkaz:
http://arxiv.org/abs/2402.12054
A typical approach to tackle stochastic control problems with partial observation is to separate the control and estimation tasks. However, it is well known that this separation generally fails to deliver an actual optimal solution for risk-sensitive
Externí odkaz:
http://arxiv.org/abs/2304.08910
APP dyshomeostasis in the pathogenesis of Alzheimer’s disease: implications for current drug targets
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-7 (2024)
Abstract The Amyloid precursor protein (APP) is a transmembrane glycoprotein from which amyloid-β (Aβ) peptides are generated after proteolytic cleavage. Aβ peptides are the main constituent of amyloid plaques in Alzheimer’s Disease (AD). The ph
Externí odkaz:
https://doaj.org/article/3f574d1ada5b4db0a4ccbeda43098be2
Autor:
Javier Arranz, Nuole Zhu, Sara Rubio-Guerra, Íñigo Rodríguez-Baz, Rosa Ferrer, María Carmona-Iragui, Isabel Barroeta, Ignacio Illán-Gala, Miguel Santos-Santos, Juan Fortea, Alberto Lleó, Mireia Tondo, Daniel Alcolea
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-15 (2024)
Abstract Background Recently developed blood markers for Alzheimer's disease (AD) detection have high accuracy but usually require ultra-sensitive analytic tools not commonly available in clinical laboratories, and their performance in clinical pract
Externí odkaz:
https://doaj.org/article/793bf88a8b9d4e4ab55c24350b061c59
Autor:
Schartel, Norbert, González-Riestra, Rosario, Kretschmar, Peter, Kirsch, Marcus, Rodríguez-Pascual, Pedro, Rosen, Simon, Santos-Lleó, Maria, Smith, Michael, Stuhlinger, Martin, Verdugo-Rodrigo, Eva
The X-ray Multi-mirror Mission (XMM-Newton) provides simultaneous non-dispersive spectroscopic X-ray imaging and timing, medium resolution dispersive X-ray spectroscopy and optical/UV imaging, spectroscopy and timing. In combination, the imaging came
Externí odkaz:
http://arxiv.org/abs/2212.10995
Autor:
Kollatschny, Wolfram, Grupe, Dirk, Parker, Michael L., Ochmann, Martin W., Schartel, Norbert, Romero-Colmenero, Encarni, Winkler, Hartmut, Komossa, Stefanie, Famula, Philipp, Probst, Malte A., Santos-Lleo, Maria
Publikováno v:
A&A 670, A103 (2023)
IRAS23226-3843 has previously been classified as a changing-look AGN based on X-ray and optical spectral variations. In 2019, Swift observations revealed a strong rebrightening in X-ray and UV fluxes in comparison to observations in 2017. We took fol
Externí odkaz:
http://arxiv.org/abs/2212.07270
Autor:
Amanda Cano, María Capdevila, Raquel Puerta, Javier Arranz, Laura Montrreal, Itziar de Rojas, Pablo García-González, Claudia Olivé, Fernando García-Gutiérrez, Oscar Sotolongo-Grau, Adelina Orellana, Nuria Aguilera, Maribel Ramis, Maitee Rosende-Roca, Alberto Lleó, Juan Fortea, Juan Pablo Tartari, Asunción Lafuente, Liliana Vargas, Alba Pérez-Cordón, Nathalia Muñoz, Ángela Sanabria, Montserrat Alegret, Xavier Morató, Lluís Tárraga, Victoria Fernández, Marta Marquié, Sergi Valero, Daniel Alcolea, Mercè Boada, Agustín Ruiz
Publikováno v:
EBioMedicine, Vol 108, Iss , Pp 105345- (2024)
Summary: Background: The identification of patients with an elevated risk of developing Alzheimer's disease (AD) dementia and eligible for the disease-modifying treatments (DMTs) in the earliest stages is one of the greatest challenges in the clinica
Externí odkaz:
https://doaj.org/article/ea62dd3fe9524f3a9be6195fdbea9857
Autor:
Imogen J. Swift, Rosa Rademakers, NiCole Finch, Matt Baker, Roberta Ghidoni, Luisa Benussi, Giuliano Binetti, Giacomina Rossi, Matthis Synofzik, Carlo Wilke, David Mengel, Caroline Graff, Leonel T. Takada, Raquel Sánchez-Valle, Anna Antonell, Daniela Galimberti, Chiara Fenoglio, Maria Serpente, Marina Arcaro, Stefanie Schreiber, Stefan Vielhaber, Philipp Arndt, Isabel Santana, Maria Rosario Almeida, Fermín Moreno, Myriam Barandiaran, Alazne Gabilondo, Johannes Stubert, Estrella Gómez-Tortosa, Pablo Agüero, M. José Sainz, Tomohito Gohda, Maki Murakoshi, Nozomu Kamei, Sarah Kittel-Schneider, Andreas Reif, Johannes Weigl, Jinlong Jian, Chuanju Liu, Ginette Serrero, Thomas Greither, Gerit Theil, Ebba Lohmann, Stefano Gazzina, Silvia Bagnoli, Giovanni Coppola, Amalia Bruni, Mirja Quante, Wieland Kiess, Andreas Hiemisch, Anne Jurkutat, Matthew S. Block, Aaron M. Carlson, Geir Bråthen, Sigrid Botne Sando, Gøril Rolfseng Grøntvedt, Camilla Lauridsen, Amanda Heslegrave, Carolin Heller, Emily Abel, Alba Gómez-Núñez, Roger Puey, Andrea Arighi, Enmanuela Rotondo, Lize C. Jiskoot, Lieke H. H. Meeter, João Durães, Marisa Lima, Miguel Tábuas-Pereira, João Lemos, Bradley Boeve, Ronald C. Petersen, Dennis W. Dickson, Neill R. Graff-Radford, Isabelle LeBer, Leila Sellami, Foudil Lamari, Fabienne Clot, Barbara Borroni, Valentina Cantoni, Jasmine Rivolta, Alberto Lleó, Juan Fortea, Daniel Alcolea, Ignacio Illán-Gala, Lucie Andres-Cerezo, Philip Van Damme, Jordi Clarimon, Petra Steinacker, Emily Feneberg, Markus Otto, Emma L. van der Ende, John C. van Swieten, Harro Seelaar, Henrik Zetterberg, Aitana Sogorb-Esteve, Jonathan D. Rohrer
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-13 (2024)
Abstract Background Pathogenic heterozygous mutations in the progranulin gene (GRN) are a key cause of frontotemporal dementia (FTD), leading to significantly reduced biofluid concentrations of the progranulin protein (PGRN). This has led to a number
Externí odkaz:
https://doaj.org/article/1d7c751ac55c494a90e49ef788756561
Autor:
Christos Skevas, Nicolás Pérez de Olaguer, Albert Lleó, David Thiwa, Ulrike Schroeter, Inês Valente Lopes, Luca Mautone, Stephan J. Linke, Martin Stephan Spitzer, Daniel Yap, Di Xiao
Publikováno v:
BMC Ophthalmology, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background Artificial intelligence (AI) has the potential to increase the affordability and accessibility of eye disease screening, especially with the recent approval of AI-based diabetic retinopathy (DR) screening programs in several count
Externí odkaz:
https://doaj.org/article/7e5cff725f1241c2b4c305e4ff1b5ce9