Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Ll, Houston"'
Autor:
LL Houston
Publikováno v:
Current Opinion in Biotechnology. 4:739-744
Significant progress has been made in our understanding of some of the important physiological and pharmacological barriers that limit immunoconjugate efficacy. Recent successes obtained employing immunotoxins in the treatment of leukemia and lymphom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32befa9682548db685e513eda8440d4e
https://doi.org/10.1016/0958-1669(93)90059-6
https://doi.org/10.1016/0958-1669(93)90059-6
Autor:
Virginia M. Kuebelbeck, Lisa M. Chelstrom, LL Houston, Dorothea E. Myers, Roland Gunther, F. M. Uckun, J. D. Irvin, Jo Anne H. Young, Dale Finnegan
Publikováno v:
Blood. 79:2649-2661
We show that a highly aggressive subclone of murine BCL-1 B-lineage leukemia expresses a single 2.4-kb transcript hybridizing to the human CD19 cDNA probe and reacts strongly with the anti-human CD19 monoclonal antibodies (MoAb) B43, B4, Leu-12, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3525fb4ff18a88b9e9217513aa9f8810
https://doi.org/10.1182/blood.v79.10.2649.2649
https://doi.org/10.1182/blood.v79.10.2649.2649
Autor:
S Ramakrishnan, LL Houston
Publikováno v:
Science (New York, N.Y.). 223(4631)
Immunotoxins containing pokeweed antiviral protein and monoclonal antibodies against human T cells or human transferrin receptor efficiently killed acute lymphoblastic leukemia cells. Chloroquine specifically enhanced the rate of protein synthesis in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aa1cb14f436017d25b5dfd2181991cc
https://pubmed.ncbi.nlm.nih.gov/6318313
https://pubmed.ncbi.nlm.nih.gov/6318313
Publikováno v:
Europe PubMed Central
An immunotoxin was synthesized with pokeweed antiviral protein and an IgG1 monoclonal antibody directed against human B and pre-B cells. The B43 murine monoclonal antibody does not react with normal human bone marrow precursor cells. The immunotoxin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::8fb412b4ba4925da8175095d838568fd
https://pubmed.ncbi.nlm.nih.gov/3855433
https://pubmed.ncbi.nlm.nih.gov/3855433
Autor:
Eo, Gregg, Sh, Bridges, Rj, Youle, Dl, Longo, Ll, Houston, Mj, Glennie, Freda Stevenson, Green I
Publikováno v:
Europe PubMed Central
The therapeutic efficacy of whole ricin, or recombinant ricin A chain, coupled to a monoclonal antibody that reacts with the idiotype of the surface IgM expressed on guinea pig L2C lymphoblasts, was assessed. In vitro studies were done to characteriz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::7e226c61fc56651a4a4cccd644d131eb
https://pubmed.ncbi.nlm.nih.gov/3495593
https://pubmed.ncbi.nlm.nih.gov/3495593
Autor:
Fatih M. Uckun, Lm, Chelstrom, Jd, Irvin, Finnegan D, Gunther R, Young J, Kuebelbeck V, Myers DE, Ll, Houston
Publikováno v:
Europe PubMed Central
We show that a highly aggressive subclone of murine BCL-1 B-lineage leukemia expresses a single 2.4-kb transcript hybridizing to the human CD19 cDNA probe and reacts strongly with the anti-human CD19 monoclonal antibodies (MoAb) B43, B4, Leu-12, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd92128451ff44990259826834dc4f48
http://europepmc.org/abstract/med/1375109
http://europepmc.org/abstract/med/1375109
Publikováno v:
Europe PubMed Central
The ex vivo anti-leukemic efficacy and stem cell toxicity of two different T cell directed immunotoxins containing pokeweed antiviral protein (PAP) were studied by clonal assays. 5E9-11-PAP, an immunotoxin directed against human transferrin receptors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::88eaf438f3491b10eb993305d475c8de
http://europepmc.org/abstract/med/3900212
http://europepmc.org/abstract/med/3900212
Publikováno v:
Europe PubMed Central
Leukemia cells were mixed with normal human bone marrow cells to simulate bone marrow from leukemia patients; the mixture was then treated with a combination of stabilized derivative of cyclophosphamide [Mafosfamide (ASTA Z 7557)] and pokeweed antivi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e93fde419c114146caf0f879de6e13a1
http://europepmc.org/abstract/med/3871174
http://europepmc.org/abstract/med/3871174
Autor:
Js, Huston, Andrew George, Gp, Adams, Wf, Stafford, Jamar F, Ms, Tai, Je, Mccartney, Oppermann H, Bt, Heelan, Am, Peters, Ll, Houston, Ma, Bookman, Ej, Wolf, Lm, Weiner
Publikováno v:
Europe PubMed Central
The availability of engineered antibody species has catalyzed new developments in radioimmunotargeting. This chapter summarized recent studies of single-chain Fv (sFv) proteins, which are minimal antibody binding sites engineered as single polypeptid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::be0a7986eb548391a296820429d4f1ce
http://europepmc.org/abstract/med/8961808
http://europepmc.org/abstract/med/8961808
Autor:
Adams GP; Department of Medical Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA. gp_adams@fccc.edu, Tai MS, McCartney JE, Marks JD, Stafford WF 3rd, Houston LL, Huston JS, Weiner LM
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2006 Mar 01; Vol. 12 (5), pp. 1599-605.