Disturbed Cardiac Metabolism Triggers Atrial Arrhythmogenesis in Diabetes Mellitus: Energy Substrate Alternate as a Potential Therapeutic Intervention.

Autor: Lkhagva B; Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan., Lee TW; Division of Endocrinology and Metabolism, Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan.; Division of Endocrinology and Metabolism, Department of Internal Medicine, Wan Fang Hospital, Taipei Medical University, Taipei 11696, Taiwan., Lin YK; Division of Cardiology, Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan., Chen YC; Department of Biomedical Engineering, National Defense Medical Center, Taipei 11490, Taiwan., Chung CC; Division of Cardiology, Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan., Higa S; Cardiac Electrophysiology and Pacing Laboratory, Division of Cardiovascular Medicine, Makiminato Central Hospital, Okinawa 901-2131, Japan., Chen YJ; Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan.; Cardiovascular Research Center, Wan-Fang Hospital, Taipei Medical University, Taipei 11696, Taiwan.

Publikováno v: Cells [Cells] 2022 Sep 18; Vol. 11 (18). Date of Electronic Publication: 2022 Sep 18.

GQ262 Attenuates Pathological Cardiac Remodeling by Downregulating the Akt/mTOR Signaling Pathway.

Autor: Ma, Haoyue^1,2,3,4,5 (AUTHOR) haoyue.ma888@gmail.com, Ge, Yang⁶ (AUTHOR), Di, Chang^1,2,3,4,5 (AUTHOR), Wang, Xin^1,2,3,4,5 (AUTHOR), Qin, Boyang^1,2,3,4,5 (AUTHOR), Wang, Anhui^1,2,3,4,5 (AUTHOR), Hu, Weipeng^1,2,3,4,5 (AUTHOR), Lai, Zirui^1,2,3,4,5 (AUTHOR), Xiong, Xiaofeng⁶ (AUTHOR) xiongxf7@mail.sysu.edu.cn, Qi, Rong^1,2,3,4,5 (AUTHOR) xiongxf7@mail.sysu.edu.cn

Publikováno v: International Journal of Molecular Sciences. Oct2024, Vol. 25 Issue 19, p10297. 18p.

Histone deacetylase 6 as a novel promising target to treat cardiovascular disease.

Autor: Wu, Ya‐Xi¹ (AUTHOR), Li, Bing‐Qian¹ (AUTHOR), Yu, Xiao‐Qian¹ (AUTHOR), Liu, Yu‐Lin¹ (AUTHOR), Chui, Rui‐Hao¹ (AUTHOR), Sun, Kai¹ (AUTHOR), Geng, Dian‐Guang² (AUTHOR), Ma, Li‐Ying^1,2 (AUTHOR) maliying@zzu.edu.cn

Publikováno v: Cancer Innovation. Jun2024, Vol. 3 Issue 3, p1-15. 15p.

Activation of Class I histone deacetylases contributes to mitochondrial dysfunction in cardiomyocytes with altered complex activities.

Autor: Lkhagva B; a Graduate Institute of Clinical Medicine, College of Medicine , Taipei Medical University , Taipei , Taiwan.; b Department of Cardiology, School of Medicine , Mongolian National University of Medical Sciences , Ulaanbaatar , Mongolia., Kao YH; a Graduate Institute of Clinical Medicine, College of Medicine , Taipei Medical University , Taipei , Taiwan.; c Department of Medical Education and Research , Wan Fang Hospital , Taipei Medical University , Taipei , Taiwan., Lee TI; d Division of Endocrinology and Metabolism , Department of General Medicine , School of Medicine, College of Medicine , Taipei Medical University , Taipei , Taiwan.; e Department of Internal Medicine , Wan Fang Hospital , Taipei Medical University , Taipei , Taiwan., Lee TW; a Graduate Institute of Clinical Medicine, College of Medicine , Taipei Medical University , Taipei , Taiwan.; f Division of Endocrinology and Metabolism, Department of Internal Medicine , Wan Fang Hospital , Taipei Medical University , Taipei , Taiwan., Cheng WL; a Graduate Institute of Clinical Medicine, College of Medicine , Taipei Medical University , Taipei , Taiwan., Chen YJ; a Graduate Institute of Clinical Medicine, College of Medicine , Taipei Medical University , Taipei , Taiwan.; g Division of Cardiovascular Medicine, Department of Internal Medicine , Wan Fang Hospital , Taipei Medical University , Taipei , Taiwan.

Publikováno v: Epigenetics [Epigenetics] 2018; Vol. 13 (4), pp. 376-385. Date of Electronic Publication: 2018 May 03.

Targeting histone deacetylases: A novel therapeutic strategy for atrial fibrillation.

Autor: Lkhagva B; Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan., Kao YH; Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan; Department of Medical Education and Research, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan., Chen YC; Department of Biomedical Engineering, National Defense Medical Center, Taipei, Taiwan., Chao TF; Division of Cardiology and Cardiovascular Research Center, Taipei Veterans General Hospital, Taipei, Taiwan., Chen SA; Division of Cardiology and Cardiovascular Research Center, Taipei Veterans General Hospital, Taipei, Taiwan; School of Medicine, National Yang-Ming University, Taipei, Taiwan., Chen YJ; Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan; Division of Cardiovascular Medicine, Department of Internal Medicine, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan. Electronic address: yjchen@tmu.edu.tw.

Publikováno v: European journal of pharmacology [Eur J Pharmacol] 2016 Jun 15; Vol. 781, pp. 250-7. Date of Electronic Publication: 2016 Apr 16.