Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Ljubica Caldovic"'
Autor:
Matthew S. Bramble, Victor Fourcassié, Neerja Vashist, Florence Roux-Dalvai, Yun Zhou, Guy Bumoko, Michel Lupamba Kasendue, D’Andre Spencer, Hilaire Musasa Hanshi-Hatuhu, Vincent Kambale-Mastaki, Rafael Vincent M. Manalo, Aliyah Mohammed, David R. McIlwain, Gary Cunningham, Marshall Summar, Michael J. Boivin, Ljubica Caldovic, Eric Vilain, Dieudonne Mumba-Ngoyi, Desire Tshala-Katumbay, Arnaud Droit
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Konzo is a neglected paralytic neurological disease associated with food (cassava) poisoning that affects the world’s poorest children and women of childbearing ages across regions of sub-Saharan Africa. Despite understanding the dietary f
Externí odkaz:
https://doaj.org/article/4668fa1a6b5f4299a659ef2961f0a97d
Autor:
Kara Simpson, Nicholas Ah Mew, Ljubica Caldovic, Annette Feigenbaum, Raquel Fernandez, Emily Groopman, Andrea Gropman, Emily Kudalkar, Uta Lichter-Konecki, McKenna Kyriss, Elaine Spector, Meredith Weaver, Manya Warrier, Diane Zastrow, Amanda Thomas-Wilson
Publikováno v:
Genetics in Medicine Open, Vol 2, Iss , Pp 100884- (2024)
Externí odkaz:
https://doaj.org/article/cd6c80da050b43fc9abb2af511554055
Autor:
Naoe Harafuji, Chaozhe Yang, Maoqing Wu, Girija Thiruvengadam, Heather Gordish-Dressman, R. Griffin Thompson, P. Darwin Bell, Avi Z. Rosenberg, Claudia Dafinger, Max C. Liebau, Zsuzsanna Bebok, Ljubica Caldovic, Lisa M. Guay-Woodford
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Autosomal recessive polycystic kidney disease (ARPKD; MIM#263200) is a severe, hereditary, hepato-renal fibrocystic disorder that leads to early childhood morbidity and mortality. Typical forms of ARPKD are caused by pathogenic variants in the PKHD1
Externí odkaz:
https://doaj.org/article/30852107202d4088b3304c8e12f24d6b
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2023)
Transcription factor Ap2b (TFAP2B), an AP-2 family transcription factor, binds to the palindromic consensus DNA sequence, 5′-GCCN3-5GGC-3’. Mice lacking functional Tfap2b gene die in the perinatal or neonatal period with cystic dilatation of the
Externí odkaz:
https://doaj.org/article/1702849f192743c885b04e9da28ad2a7
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6754 (2023)
Urea cycle enzymes and transporters collectively convert ammonia into urea in the liver. Aberrant overexpression of carbamylphosphate synthetase 1 (CPS1) and SLC25A13 (citrin) genes has been associated with faster proliferation of tumor cells due to
Externí odkaz:
https://doaj.org/article/26f826c2417540b9b8aa0892f2061a82
Autor:
Hans G. Pohl, Suzanne L. Groah, Marcos Pérez-Losada, Inger Ljungberg, Bruce M. Sprague, Neel Chandal, Ljubica Caldovic, Michael Hsieh
Publikováno v:
International Neurourology Journal, Vol 24, Iss 1, Pp 41-51 (2020)
Purpose Compared to the microbiome of other body sites, the urinary microbiome remains poorly understood. Although noninvasive voided urine specimens are convenient, contamination by urethral microbiota may confound understanding of the bladder micro
Externí odkaz:
https://doaj.org/article/989ad047d8c345289c7f45c68d432f2d
Autor:
Nantaporn Haskins, Shivaprasad Bhuvanendran, Claudio Anselmi, Anna Gams, Tomas Kanholm, Kristen M. Kocher, Jonathan LoTempio, Kylie I. Krohmaly, Danielle Sohai, Nathaniel Stearrett, Erin Bonner, Mendel Tuchman, Hiroki Morizono, Jyoti K. Jaiswal, Ljubica Caldovic
Publikováno v:
Frontiers in Physiology, Vol 11 (2021)
Mitochondrial enzymes involved in energy transformation are organized into multiprotein complexes that channel the reaction intermediates for efficient ATP production. Three of the mammalian urea cycle enzymes: N-acetylglutamate synthase (NAGS), carb
Externí odkaz:
https://doaj.org/article/d0513014ca26433bbf1cf3d4ad8f47b7
Publikováno v:
Biology, Vol 7, Iss 2, p 34 (2018)
Carbamyl phosphate (CP) is well-known as an essential intermediate of pyrimidine and arginine/urea biosynthesis. Chemically, CP can be easily synthesized from dihydrogen phosphate and cyanate. Enzymatically, CP can be synthesized using three differen
Externí odkaz:
https://doaj.org/article/4b2a0128c94740dabc8a4d4d937bb075
Autor:
Ljubica Caldovic, Nantaporn Haskins, Amy Mumo, Himani Majumdar, Mary Pinter, Mendel Tuchman, Alison Krufka
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85597 (2014)
The urea cycle converts ammonia, a waste product of protein catabolism, into urea. Because fish dispose ammonia directly into water, the role of the urea cycle in fish remains unknown. Six enzymes, N-acetylglutamate synthase (NAGS), carbamylphosphate
Externí odkaz:
https://doaj.org/article/0b06fc64d3f745608fe8733f7a0137a0
Autor:
Sandra Kirsch Heibel, Giselle Yvette Lopez, Maria Panglao, Sonal Sodha, Leonardo Mariño-Ramírez, Mendel Tuchman, Ljubica Caldovic
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e29527 (2012)
The urea cycle converts toxic ammonia to urea within the liver of mammals. At least 6 enzymes are required for ureagenesis, which correlates with dietary protein intake. The transcription of urea cycle genes is, at least in part, regulated by glucoco
Externí odkaz:
https://doaj.org/article/98e44622116e4d6189b1b6e830f3f4b6