Výsledky vyhledávání - "Lj, Bridgeman"

p16/p14(ARF) cell cycle regulatory pathways in primary neuroblastoma: p16 expression is associated with advanced stage disease

Autor: Omura-Minamisawa M, Mb, Diccianni, Rc, Chang, Batova A, Lj, Bridgeman, Schiff J, Sl, Cohn, Wb, London, alice yu

Publikováno v: Europe PubMed Central

p16 regulates the G(1)-S cell cycle transition by inhibiting the cyclin D-cyclin-dependent kinase (CDK)4/CDK6-mediated phosphorylation of retinoblastoma protein (pRb). We examined the possible derangement of the p16-CDK/cyclin D-pRb pathway in 40 pri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::07aa07ab1c72eaae1f251ddf465f5557
https://pubmed.ncbi.nlm.nih.gov/11705866

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Universal inactivation of both p16 and p15 but not downstream components is an essential event in the pathogenesis of T-cell acute lymphoblastic leukemia

Autor: Omura-Minamisawa M, Mb, Diccianni, Batova A, Rc, Chang, Lj, Bridgeman, Yu J, Pullen J, Wp, Bowman, alice yu

Publikováno v: Europe PubMed Central

p16/p15 regulate the cell cycle pathway by inhibiting the cyclin Ds-CDK4/6 mediated phosphorylation of pRb. We reported previously that in T-cell acute lymphoblastic leukemia (T-ALL), p16 and p15 were frequently (approximately 70%) inactivated at the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::778fdb093decabc4741ee7f8b6bc4df9
https://pubmed.ncbi.nlm.nih.gov/10778944

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In vitro sensitivity of T-cell lymphoblastic leukemia to UCN-01 (7-hydroxystaurosporine) is dependent on p16 protein status: a Pediatric Oncology Group study

Autor: Omura-Minamisawa M, Mb, Diccianni, Batova A, Rc, Chang, Lj, Bridgeman, Yu J, de Wit E, Fh, Kung, Jd, Pullen, alice yu

Publikováno v: Europe PubMed Central

p16 regulates the cell cycle pathway by inhibiting the cyclin Ds-cyclin-dependent kinase (CDK) 4/6-mediated phosphorylation of retinoblastoma protein (pRb). Previously, we reported that most primary T-cell acute lymphoblastic leukemia (T-ALL) harbore

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::3b68deb2e2dab82f08ca6aaecc7c9444
http://europepmc.org/abstract/med/11118035

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Use of alanosine as a methylthioadenosine phosphorylase-selective therapy for T-cell acute lymphoblastic leukemia in vitro

Autor: Batova A, Mb, Diccianni, Omura-Minamisawa M, Yu J, Cj, Carrera, Lj, Bridgeman, Fh, Kung, Pullen J, Md, Amylon, alice yu

Publikováno v: Europe PubMed Central

Methylthioadenosine phosphorylase (MTAP) is an important enzyme for the salvage of adenine and methionine and is deficient in a variety of cancers including T-cell acute lymphocytic leukemia (T-ALL). Previously, we reported that the MTAP gene was del

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::169ad6c1e143f50f1fce8eb501ebd332
http://europepmc.org/abstract/med/10197619

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Akademický článek

In vitro sensitivity of T-cell lymphoblastic leukemia to UCN-01 (7-hydroxystaurosporine) is dependent on p16 protein status: a Pediatric Oncology Group study.

Autor: Omura-Minamisawa M; Department of Pediatrics/Hematology-Oncology, University of California, San Diego 92103-8447, USA., Diccianni MB, Batova A, Chang RC, Bridgeman LJ, Yu J, de Wit E, Kung FH, Pullen JD, Yu AL

Publikováno v: Cancer research [Cancer Res] 2000 Dec 01; Vol. 60 (23), pp. 6573-6.

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Akademický článek

Use of alanosine as a methylthioadenosine phosphorylase-selective therapy for T-cell acute lymphoblastic leukemia in vitro.

Autor: Batova A; Department of Pediatric Hematology/Oncology, University of California, San Diego 92103-8447, USA., Diccianni MB, Omura-Minamisawa M, Yu J, Carrera CJ, Bridgeman LJ, Kung FH, Pullen J, Amylon MD, Yu AL

Publikováno v: Cancer research [Cancer Res] 1999 Apr 01; Vol. 59 (7), pp. 1492-7.

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