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pro vyhledávání: '"Lizette C.M. Haazen"'
Autor:
Ulrich Beuers, Michael Trauner, Stan F.J. van de Graaf, Claudia D. Fuchs, Ronald P.J. Oude Elferink, Davor Slijepcevic, Reinout L.P. Roscam Abbing, Lizette C.M. Haazen
Publikováno v:
Hepatology (Baltimore, Md.), 68(3), 1057-1069. John Wiley and Sons Ltd
Hepatology (Baltimore, Md.)
Hepatology (Baltimore, Md.)
Accumulation of bile salts (BSs) during cholestasis leads to hepatic and biliary injury, driving inflammatory and fibrotic processes. The Na+ -Taurocholate Cotransporting Polypeptide (NTCP) is the major hepatic uptake transporter of BSs, and can be s