Reduced experimental autoimmune encephalomyelitis after intranasal and oral administration of recombinant lactobacilli expressing myelin antigens

Autor: Conny van Holten-Neelen, Jon D. Laman, Linsy Hoogteijling, Wim J. A. Boersma, C.B.M. Maassen, Lizette Visser, Eric Claassen, M.M. Schellekens, Lizet Groenewegen

Publikováno v: Vaccine, 21(32), 4685-4693
Maassen, C B M, Laman, J D, van Holten-Neelen, C, Hoogteijling, L, Groenewegen, L, Visser, L, Schellekens, M M, Boersma, W J A & Claassen, E H J H M 2003, ' Reduced experimental autoimmune encephalomyelitis after intranasal and oral administration of recombinant lactobacilli expressing myelin antigens ', Vaccine, vol. 21, no. 32, pp. 4685-93 . https://doi.org/10.1016/S0264-410X(03)00522-X
Vaccine, 21(32), 4685-93. Elsevier BV
Vaccine 21 (2003) 32
Vaccine, 21, 4685-4693. Elsevier

Oral administration of autoantigens is a safe and convenient way to induce peripheral T-cell tolerance in autoimmune diseases like multiple sclerosis (MS). To increase the efficacy of oral tolerance induction and obviate the need for large-scale puri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea097cfd47c6489fccd57e4b7ec90d37
https://doi.org/10.1016/s0264-410x(03)00522-x