Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Lizdany Florez-Alvarez"'
In vitro and in silico evaluation of antiretrovirals against SARS-CoV-2: A drug repurposing approach
Autor:
Maria I. Zapata-Cardona, Lizdany Florez-Alvarez, Ariadna L. Guerra-Sandoval, Mateo Chvatal-Medina, Carlos M. Guerra-Almonacid, Jaime Hincapie-Garcia, Juan C. Hernandez, Maria T. Rugeles, Wildeman Zapata-Builes
Publikováno v:
AIMS Microbiology, Vol 9, Iss 1, Pp 20-40 (2023)
Background: Drug repurposing is a valuable strategy for rapidly developing drugs for treating COVID-19. This study aimed to evaluate the antiviral effect of six antiretrovirals against SARS-CoV-2 in vitro and in silico. Methods: The cytotoxicity
Externí odkaz:
https://doaj.org/article/0638fc4e7acc4b158a2372696f49d638
Autor:
Claudia Urueña, Ricardo Ballesteros-Ramírez, Alejandra Gomez-Cadena, Alfonso Barreto, Karol Prieto, Sandra Quijano, Pablo Aschner, Carlos Martínez, Maria I. Zapata-Cardona, Hajar El-Ahanidi, Camilla Jandus, Lizdany Florez-Alvarez, Maria Teresa Rugeles, Wildeman Zapata-Builes, Angel Alberto Garcia, Susana Fiorentino
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
BackgroundIt has been proposed that polyphenols can be used in the development of new therapies against COVID-19, given their ability to interfere with the adsorption and entrance processes of the virus, thus disrupting viral replication. Seeds from
Externí odkaz:
https://doaj.org/article/2377c79ca1e8442f99e57c31f9b02e47
Autor:
Ruben Dario Arias Perez, Nataly Arboleda-Álvarez, Catalina Sánchez-Gómez, Lizdany Florez-Alvarez, Damariz Marín-Palma, Natalia A. Taborda, Juan C. Hernandez
Publikováno v:
Kasmera, Vol 49, Iss 1 (2021)
Considerando que la terapia antirretroviral no logra controlar la activación inmune que ocurre durante la infección por VIH-1, el estudio de moléculas inmunomoduladoras puede proporcionar estrategias alternativas para su control. En este sentido,
Externí odkaz:
https://doaj.org/article/b81b8713e9754e9a98db4caa6fba2b08
Autor:
Patrick Y. A. Reinke, Edmarcia Elisa de Souza, Sebastian Günther, Sven Falke, Julia Lieske, Wiebke Ewert, Jure Loboda, Alexander Herrmann, Aida Rahmani Mashhour, Katarina Karničar, Aleksandra Usenik, Nataša Lindič, Andreja Sekirnik, Viviane Fongaro Botosso, Gláucia Maria Machado Santelli, Josana Kapronezai, Marcelo Valdemir de Araújo, Taiana Tainá Silva-Pereira, Antônio Francisco de Souza Filho, Mariana Silva Tavares, Lizdany Flórez-Álvarez, Danielle Bruna Leal de Oliveira, Edison Luiz Durigon, Paula Roberta Giaretta, Marcos Bryan Heinemann, Maurice Hauser, Brandon Seychell, Hendrik Böhler, Wioletta Rut, Marcin Drag, Tobias Beck, Russell Cox, Henry N. Chapman, Christian Betzel, Wolfgang Brehm, Winfried Hinrichs, Gregor Ebert, Sharissa L. Latham, Ana Marcia de Sá Guimarães, Dusan Turk, Carsten Wrenger, Alke Meents
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-13 (2023)
Abstract Several drug screening campaigns identified Calpeptin as a drug candidate against SARS-CoV-2. Initially reported to target the viral main protease (Mpro), its moderate activity in Mpro inhibition assays hints at a second target. Indeed, we s
Externí odkaz:
https://doaj.org/article/959ee7d783844cc0965882267049dc4f
Autor:
Daniel S. Rincón, Lizdany Flórez-Álvarez, Natalia A. Taborda, Juan C. Hernandez, María T. Rugeles, Wildeman Zapata-Builes
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Despite being under constant exposure to HIV-1, some individuals do not show serological or clinical evidence of infection and are known as HESN (HIV-Exposed Seronegative). Multiple studies in different HESN cohorts have linked the NK cells
Externí odkaz:
https://doaj.org/article/8fa4cd0b6722407494196a8057b50774
Autor:
Lizdany Flórez-Álvarez, Juan C. Hernández, Wildeman Zapata, José Iván Charry- Zuluaga, José R. Jaramillo, Natalia A. Taborda, Juan D. González, Larry L. Martínez, Lina M. Yassin
Publikováno v:
Iatreia, Vol 36, Iss 1, Pp 5-15 (2023)
Introduction: COVID-19 is an acute respiratory tract disease caused by the emerging coronavirus SARS-CoV-2. Although several options for chemoprophylaxis are under development, effective treatment for COVID-19 is not yet available. Objective: To inv
Externí odkaz:
https://doaj.org/article/c64cacff9e6043eb95f68c18c515cc39
Autor:
María I. Zapata-Cardona, Lizdany Flórez-Álvarez, Tulio J. Lopera, Mateo Chvatal-Medina, Wildeman Zapata-Builes, Francisco J. Diaz, Wbeimar Aguilar-Jimenez, Natalia Taborda, Juan C. Hernandez, Maria T. Rugeles
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The emergence of the Omicron variant has generated concerns about the efficacy of COVID-19 vaccines. We evaluated the serum neutralizing activity of antibodies against the Omicron (lineage BA.1.1) by plaque reduction neutralizing test, as well as its
Externí odkaz:
https://doaj.org/article/55ba9fb3ad594814a59b783c914101d3
Autor:
Wbeimar Aguilar-Jiménez, Lizdany Flórez-Álvarez, Daniel S. Rincón, Damariz Marín-Palma, Alexandra Sánchez-Martínez, Jahnnyer Martínez, María Isabel Zapata, John D. Loaiza, Constanza Cárdenas, Fanny Guzmán, Paula A. Velilla, Natalia A. Taborda, Wildeman Zapata, Juan C. Hernández, Francisco J. Díaz, María T. Rugeles
Publikováno v:
Biomédica: revista del Instituto Nacional de Salud, Vol 41, Iss Sp. 2, Pp 86-102 (2021)
Introduction: Immunological markers have been described during COVID-19 and persist after recovery. These immune markers are associated with clinical features among SARSCoV-2 infected individuals. Nevertheless, studies reporting a comprehensive analy
Externí odkaz:
https://doaj.org/article/1091ede54c9245c7a794ff3ae63ff6fe
Autor:
Lizdany Flórez-Álvarez, Edmarcia Elisa de Souza, Viviane Fongaro Botosso, Danielle Bruna Leal de Oliveira, Paulo Lee Ho, Carlos Pelleschi Taborda, Giuseppe Palmisano, Margareth Lara Capurro, João Renato Rebello Pinho, Helena Lage Ferreira, Paola Minoprio, Eurico Arruda, Luís Carlos de Souza Ferreira, Carsten Wrenger, Edison Luiz Durigon
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Hemorrhagic fever viruses (HFVs) pose a threat to global public health owing to the emergence and re-emergence of highly fatal diseases. Viral hemorrhagic fevers (VHFs) caused by these viruses are mostly characterized by an acute febrile syndrome wit
Externí odkaz:
https://doaj.org/article/22e4f97efec644c296da8bf0aae66662
Autor:
Maria Isabel Zapata-Cardona, Lizdany Flórez-Álvarez, Diana Maryory Gómez-Gallego, María Juliana Moncada-Díaz, Juan Carlos Hernandez, Francisco Díaz, María Teresa Rugeles, Wbeimar Aguilar-Jiménez, Wildeman Zapata
Publikováno v:
Iranian Journal of Microbiology, Vol 14, Iss 3 (2022)
Background and Objectives: SARS-CoV-2 variants of concern (VOC) and interest (VOI) pose a significant threat to public health because the rapid change in the SARS-CoV-2 genome can alter viral phenotypes such as virulence, transmissibility and the abi
Externí odkaz:
https://doaj.org/article/e0b358d0cfd644c2b9373ed6f9f79b31