Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Lizandra Jimenez"'
Autor:
Lizandra Jimenez, Bahnisikha Barman, Youn Jae Jung, Lauren Cocozza, Evan Krystofiak, Cherie Saffold, Kasey C. Vickers, John T. Wilson, T. Renee Dawson, Alissa M. Weaver
Publikováno v:
Journal of Extracellular Vesicles, Vol 12, Iss 11, Pp n/a-n/a (2023)
Abstract Extracellular vesicle (EV)‐carried miRNAs can influence gene expression and functional phenotypes in recipient cells. Argonaute 2 (Ago2) is a key miRNA‐binding protein that has been identified in EVs and could influence RNA silencing. Ho
Externí odkaz:
https://doaj.org/article/535c494cfba140799d73ec352ef56d94
Autor:
Selma Maacha, Ajaz A. Bhat, Lizandra Jimenez, Afsheen Raza, Mohammad Haris, Shahab Uddin, Jean-Charles Grivel
Publikováno v:
Molecular Cancer, Vol 18, Iss 1, Pp 1-16 (2019)
Abstract The tumor microenvironment represents a complex network, in which tumor cells not only communicate with each other but also with stromal and immune cells. Current research has demonstrated the vital role of the tumor microenvironment in supp
Externí odkaz:
https://doaj.org/article/dcc6e6d06ddd43788653862eecd0dc4f
Autor:
Lizandra Jimenez, Victor Stolzenbach, Patricia M. M. Ozawa, Marisol Ramirez-Solano, Qi Liu, Julien Sage, Alissa M. Weaver
Small Cell Lung Cancer (SCLC) tumors are made up of distinct cell subpopulations, including neuroendocrine (NE) and non-NE cells. While secreted factors from non-NE SCLC cells have been shown to support the growth of the NE cells, the underlying mole
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f19bde94a9756106e7b515863f6c097
https://doi.org/10.1101/2022.10.12.511984
https://doi.org/10.1101/2022.10.12.511984
Autor:
Alissa M. Weaver, Leonard A. Harris, Lizandra Jimenez, Patricia Midori Murobushi Ozawa, Samantha P. Beik
Publikováno v:
Curr Opin Syst Biol
Cancer is a complex, dynamic disease that despite recent advances remains mostly incurable. Inter- and intratumoral heterogeneity are generally considered major drivers of therapy resistance, metastasis, and treatment failure. Recent advances in high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c9a94fcf528d49222fa02eeb45d2564
https://europepmc.org/articles/PMC7343346/
https://europepmc.org/articles/PMC7343346/
Autor:
Jeffrey L. Franklin, James G. Patton, Alissa M. Weaver, Qi Liu, Lizandra Jimenez, Hui Yu, Andrew J. McKenzie
Publikováno v:
Journal of proteome research. 18(3)
Extracellular vesicles (EVs) are important mediators of cell-cell communication due to their cargo content of proteins, lipids and RNAs. We previously reported that small EVs (SEVs) called exosomes promote directed and random cell motility, invasion,
Autor:
Thomas J. Ow, Jeffrey E. Segall, Michael B. Prystowsky, Ved P. Sharma, Thomas M. Harris, John S. Condeelis, Geoffrey Childs, Lizandra Jimenez
Publikováno v:
Archives of Pathology & Laboratory Medicine. 139:1349-1361
ContextHead and neck squamous cell carcinoma (HNSCC) is a highly invasive cancer with an association with locoregional recurrence and lymph node metastasis. We have previously reported that low microRNA-375 (miR-375) expression levels correlate with
Publikováno v:
Arch Pathol Lab Med
ContextThe highly invasive properties demonstrated by head and neck squamous cell carcinoma (HNSCC) are often associated with locoregional recurrence and lymph node metastasis in patients and is a key factor leading to an expected 5-year survival rat
Autor:
Jihyeon Lim, Ruth Hogue Angeletti, Thomas J. Belbin, Nicole Kawachi, Thomas J. Ow, Thomas M. Harris, Jeffrey E. Segall, Michael B. Prystowsky, Berta Burd, Geoffrey Childs, Lizandra Jimenez
Publikováno v:
The American journal of pathology. 187(7)
Invasion is a hallmark of advanced head and neck squamous cell carcinoma (HNSCC). We previously determined that low relative miR-375 expression was associated with poor patient prognosis. HNSCC cells with increased miR-375 expression have lower invas
Autor:
Jeffrey E. Segall, Chandan Guha, Geoffrey J. Childs, Michael B. Prystowsky, Lizandra Jimenez, Thomas M. Harris, P. Boimel, Alan A. Alfieri
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 84:S668-S669
Autor:
Thomas M. Harris, Ved P. Sharma, Ruth Hogue Angeletti, Geoffrey Childs, Lizandra Jimenez, Jeffrey E. Segall, Michael B. Prystowsky, John S. Condeelis, Jihyeon Lim
Publikováno v:
Cancer Research. 74:1452-1452
Head and neck squamous cell carcinoma (HNSCC) is a highly invasive cancer, with a five-year survival rate of around 50%. Our goal is to improve patient outcome through understanding the mechanisms determining HNSCC invasiveness. Our research group pr