Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Liza Filali"'
Autor:
Andrea Michela Biolato, Liza Filali, Diogo Pereira Fernandes, Flora Moreau, Takouhie Mgrditchian, Céline Hoffmann, Clément Thomas
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The formation of a lytic immunological synapse (IS) is crucial for cytotoxic lymphocytes to accurately target and effectively eliminate malignant cells. While significant attention has been focused on the lymphocyte side of the IS, particularly its r
Externí odkaz:
https://doaj.org/article/40bc63f8a2e14f1180086ed51cbcecb9
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Cytotoxic lymphocytes (CLs), specifically cytotoxic T lymphocytes and natural killer cells, are indispensable guardians of the immune system and orchestrate the recognition and elimination of cancer cells. Upon encountering a cancer cell, CLs establi
Externí odkaz:
https://doaj.org/article/2ce692d133a94eb2bea516bfe5d57705
Autor:
Takouhie Mgrditchian, Joshua Brown-Clay, Céline Hoffmann, Tanja Müller, Liza Filali, Elena Ockfen, Xianqing Mao, Flora Moreau, Carla Pou Casellas, Tony Kaoma, Michel Mittelbronn, Clément Thomas
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
The actin cytoskeleton plays a critical role in cancer cell invasion and metastasis; however, the coordination of its multiple functions remains unclear. Actin dynamics in the cytoplasm control the formation of invadopodia, which are membrane protrus
Externí odkaz:
https://doaj.org/article/c2b8619594984cbea893d4b0fc76ae51
Publikováno v:
STAR Protocols, Vol 4, Iss 1, Pp 102104- (2023)
Summary: Here, we present a protocol to identify and quantify phosphopeptides during the dynamic formation of an immunological synapse. We describe steps for mixing isotope-labeled immune and target cells, the stabilization of cell-to-cell conjugates
Externí odkaz:
https://doaj.org/article/679234751cae4931bd448b77d7c78655
Publikováno v:
PLoS Biology, Vol 19, Iss 8 (2021)
How cytotoxic lymphocytes are protected against their own weapons during close combat with diseased target cells is an important and long-standing question in immunology. A study in this issue provides new insights into the mechanisms by which natura
Externí odkaz:
https://doaj.org/article/cb7546c9a52e438a9d79511fe98c706a
Autor:
Hannah Wurzer, Liza Filali, Céline Hoffmann, Max Krecke, Andrea Michela Biolato, Jérôme Mastio, Sigrid De Wilde, Jean Hugues François, Anne Largeot, Guy Berchem, Jérôme Paggetti, Etienne Moussay, Clément Thomas
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Natural killer (NK) cells are innate effector lymphocytes with strong antitumor effects against hematologic malignancies such as chronic lymphocytic leukemia (CLL). However, NK cells fail to control CLL progression on the long term. For effective lys
Externí odkaz:
https://doaj.org/article/6022f7d32a004eda80782d5d6124ada7
Autor:
Liza, Filali, Marie-Pierre, Puissegur, Kevin, Cortacero, Sylvain, Cussat-Blanc, Roxana, Khazen, Nathalie, Van Acker, François-Xavier, Frenois, Arnaud, Abreu, Laurence, Lamant, Nicolas, Meyer, Béatrice, Vergier, Sabina, Müller, Brienne, McKenzie, Salvatore, Valitutti
Publikováno v:
Science advances. 8(7)
Human cytotoxic T lymphocytes (CTLs) exhibit ultrarapid lytic granule secretion, but whether melanoma cells mobilize defense mechanisms with commensurate rapidity remains unknown. We used single-cell time-lapse microscopy to offer high spatiotemporal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f126a954ae6bfe1c3e0db153a9e35058
https://pubmed.ncbi.nlm.nih.gov/35171665
https://pubmed.ncbi.nlm.nih.gov/35171665
Publikováno v:
PLoS Biology, Vol 19, Iss 8, p e3001339 (2021)
PLoS Biology, Vol 19, Iss 8 (2021)
PLoS Biology, Vol 19, Iss 8 (2021)
How cytotoxic lymphocytes are protected against their own weapons during close combat with diseased target cells is an important and long-standing question in immunology. A study in this issue provides new insights into the mechanisms by which natura
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd6918169e77e7d52fd2b653e4ad1951
https://doaj.org/article/0b3fa9f16b1b48c784684bbf3fbd1b3d
https://doaj.org/article/0b3fa9f16b1b48c784684bbf3fbd1b3d
Intrinsic Resistance of Chronic Lymphocytic Leukemia Cells to NK Cell-Mediated Lysis Can Be Overcome
Autor:
Hannah, Wurzer, Liza, Filali, Céline, Hoffmann, Max, Krecke, Andrea Michela, Biolato, Jérôme, Mastio, Sigrid, De Wilde, Jean Hugues, François, Anne, Largeot, Guy, Berchem, Jérôme, Paggetti, Etienne, Moussay, Clément, Thomas
Publikováno v:
Frontiers in Immunology
Natural killer (NK) cells are innate effector lymphocytes with strong antitumor effects against hematologic malignancies such as chronic lymphocytic leukemia (CLL). However, NK cells fail to control CLL progression on the long term. For effective lys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::07af481dcb200a2763939d88174a9439
https://pubmed.ncbi.nlm.nih.gov/34108958
https://pubmed.ncbi.nlm.nih.gov/34108958
Autor:
Clément Thomas, Salvatore Valitutti, Ernesto Gargiulo, Liza Filali, Céline Hoffmann, Andrea Michela Biolato, Hannah Wurzer
The immune system protects the body against cancer by recognizing and eliminating neoplastic cells. Immune effector cells physically interact with cancer cells through a specialized membrane interface known as the immunological synapse. Such intimate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3df58eab72047a73d7412b0cd7271711
https://doi.org/10.1016/bs.ircmb.2020.07.001
https://doi.org/10.1016/bs.ircmb.2020.07.001
