Zobrazeno 1 - 10
of 150
pro vyhledávání: '"Liza, Makowski"'
Autor:
Sarah Asemota, Wendy Effah, Kirsten L. Young, Jeremiah Holt, Linnea Cripe, Suriyan Ponnusamy, Thirumagal Thiyagarajan, Dong-Jin Hwang, Yali He, Keely Mcnamara, Daniel Johnson, Yinan Wang, Brandy Grimes, Yekta Khosrosereshki, T.J. Hollingsworth, Martin D. Fleming, Frances E. Pritchard, Ashley Hendrix, Farhan Khan, Meiyun Fan, Liza Makowski, Zheng Yin, Hironobu Sasano, D. Neil Hayes, Lawrence M. Pfeffer, Duane D. Miller, Ramesh Narayanan
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113461- (2023)
Summary: Triple-negative breast cancer (TNBC) is an aggressive subtype with no targeted therapeutics. The luminal androgen receptor (LAR) subtype constitutes 15% of TNBC and is enriched for androgen receptor (AR) and AR target genes. Here, we show th
Externí odkaz:
https://doaj.org/article/ac241ea52bf347e5b56f2020cc95e398
Autor:
Sydney C. Joseph, Samson Eugin Simon, Margaret S. Bohm, Minjeong Kim, Madeline E. Pye, Boston W. Simmons, Dillon G. Graves, Stacey M. Thomas-Gooch, Ubaid A. Tanveer, Jeremiah R. Holt, Suriyan Ponnusamy, Laura M. Sipe, D. Neil Hayes, Katherine L. Cook, Ramesh Narayanan, Joseph F. Pierre, Liza Makowski
Publikováno v:
Cancers, Vol 16, Iss 7, p 1368 (2024)
Bariatric surgery is associated with improved outcomes for several cancers, including breast cancer (BC), although the mechanisms mediating this protection are unknown. We hypothesized that elevated bile acid pools detected after bariatric surgery ma
Externí odkaz:
https://doaj.org/article/ad4335c849194130bb94e4446773aa43
Autor:
Eugene B Chang, Margaret S Bohm, Laura M Sipe, Sydney C Joseph, Boston W Simmons, Madeline E Pye, Ashley M Sidebottom, Joseph F Pierre, Liza Makowski
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/98eba0532a6b4fbd82337bca478fb77a
Autor:
Mehdi Chaib, Bilal B. Hafeez, Hassan Mandil, Deidre Daria, Ajeeth K. Pingili, Sonam Kumari, Mohammed Sikander, Vivek K. Kashyap, Guo-Yun Chen, Emmanuel Anning, Manish K. Tripathi, Sheema Khan, Stephen Behrman, Murali M. Yallapu, Meena Jaggi, Liza Makowski, Subhash C. Chauhan
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-15 (2022)
The probiotic-derived siderophore, ferrichrome, enhances anti-tumor immunity and improves the efficacy of checkpoint immunotherapy in a model of pancreatic cancer by repolarizing tumor-associated macrophages to a immunostimulatory M1 phenotype.
Externí odkaz:
https://doaj.org/article/f945b76f55ec4be9afc242551058f2f7
Autor:
Laura M Sipe, Mehdi Chaib, Emily B Korba, Heejoon Jo, Mary Camille Lovely, Brittany R Counts, Ubaid Tanveer, Jeremiah R Holt, Jared C Clements, Neena A John, Deidre Daria, Tony N Marion, Margaret S Bohm, Radhika Sekhri, Ajeeth K Pingili, Bin Teng, James A Carson, D Neil Hayes, Matthew J Davis, Katherine L Cook, Joseph F Pierre, Liza Makowski
Publikováno v:
eLife, Vol 11 (2022)
Bariatric surgery is a sustainable weight loss approach, including vertical sleeve gastrectomy (VSG). Obesity exacerbates tumor growth, while diet-induced weight loss impairs progression. It remains unknown how bariatric surgery-induced weight loss i
Externí odkaz:
https://doaj.org/article/6cdf342dabec4096909e6bcc91bbf1e4
Autor:
Avtar S. Meena, Pradeep K. Shukla, Briar Bell, Francesco Giorgianni, Rebeca Caires, Carlos Fernández-Peña, Sarka Beranova, Eitaro Aihara, Marshall H. Montrose, Mehdi Chaib, Liza Makowski, Indira Neeli, Marko Z. Radic, Valeria Vásquez, Jonathan H. Jaggar, Julio F. Cordero-Morales, RadhaKrishna Rao
Publikováno v:
Cell Reports, Vol 39, Iss 11, Pp 110937- (2022)
Summary: Intestinal epithelial tight junction disruption is a primary contributing factor in alcohol-associated endotoxemia, systemic inflammation, and multiple organ damage. Ethanol and acetaldehyde disrupt tight junctions by elevating intracellular
Externí odkaz:
https://doaj.org/article/e5f537285d734a398709ecbe67fe5d88
Autor:
Prisha S. Patel, Christopher Castelow, Disha S. Patel, Syamal K. Bhattacharya, Cem Kuscu, Canan Kuscu, Liza Makowski, James D. Eason, Amandeep Bajwa
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 21, p 12993 (2022)
Triple negative breast cancer (TNBC) is one of the most aggressive cancers diagnosed amongst women with a high rate of treatment failure and a poor prognosis. Mitochondria have been found to be key players in oncogenesis and tumor progression by mech
Externí odkaz:
https://doaj.org/article/f806cc46c5a54600bd90b29aa38c4b87
Autor:
Thomas V. Rousselle, Canan Kuscu, Cem Kuscu, Kailo Schlegel, LiPing Huang, Maria Namwanje, James D. Eason, Liza Makowski, Daniel Maluf, Valeria Mas, Amandeep Bajwa
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Dendritic cells (DCs) are central in regulating immune responses of kidney ischemia-reperfusion injury (IRI), and strategies to alter DC function may provide new therapeutic opportunities. Sphingosine 1-phosphate (S1P) modulates immunity through bind
Externí odkaz:
https://doaj.org/article/e1a321347247487bb554ae50d64b3edd
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
The tumor microenvironment (TME) is a complex network of epithelial and stromal cells, wherein stromal components provide support to tumor cells during all stages of tumorigenesis. Among these stromal cell populations are myeloid cells, which are com
Externí odkaz:
https://doaj.org/article/55732d31d4244ecbb94d1d4b889e55ad
Autor:
Alessandro Porrello, Patrick L. Leslie, Emily B. Harrison, Balachandra K. Gorentla, Sravya Kattula, Subrata K. Ghosh, Salma H. Azam, Alisha Holtzhausen, Yvonne L. Chao, Michele C. Hayward, Trent A. Waugh, Sanggyu Bae, Virginia Godfrey, Scott H. Randell, Cecilia Oderup, Liza Makowski, Jared Weiss, Matthew D. Wilkerson, D. Neil Hayes, H. Shelton Earp, Albert S. Baldwin, Alisa S. Wolberg, Chad V. Pecot
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-19 (2018)
Lung squamous carcinomas (LUSC) are poorly molecularly characterized, but sub-populations show promising response to immune checkpoint inhibitors. Here, the authors identify a subset of LUSC characterized by infiltration of inflammatory monocytes, wh
Externí odkaz:
https://doaj.org/article/98a06355bdd34530b4587e1a8b9d1ffe