Zobrazeno 1 - 10 of 24 pro vyhledávání: '"Liz Straszynski"'
1
Optimization of a flow cytometry-based protocol for detection and phenotypic characterization of multipotent mesenchymal stromal cells from human bone marrow
Autor: Dennis McGonagle, Paul Emery, Sally E. Kinsey, Elena Jones, Anne English, Liz Straszynski, Frederique Ponchel
Publikováno v: Cytometry Part B: Clinical Cytometry. :391-399
Background To study the biology of rare bone marrow (BM) multipotent mesenchymal stromal cells (MSCs), recognized protocols are needed. Colony-forming unit-fibroblast (CFU-F) assays have historically been used for the enumeration of MSCs. However, th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d70f8459d87efc0f780af4220026b9b5
https://doi.org/10.1002/cyto.b.20118
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2
Proteolytic activation of the cytotoxic phenotype during human NK cell development
Autor: Michael F. McDermott, Tim D. Holmes, Liz Straszynski, Erika A. de Wynter, Peter Brett, Paul A. S. Ballard, Joseph A. Trapani, Erica B. Wilson, Josephine L. Meade, Graham P. Cook
Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 183(2)
NK cells induce apoptosis in target cells via the perforin-mediated delivery of granzyme molecules. Cytotoxic human NK cells can be generated by IL-15-mediated differentiation of CD34+ cells in vitro and these cultures have been used extensively to a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0079dc1c666210f711cbe6c848c5c7e4
https://pubmed.ncbi.nlm.nih.gov/19570824
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3
Abnormal T cell differentiation persists in patients with rheumatoid arthritis in clinical remission and predicts relapse
Autor: Liz Straszynski, Sarah L. Field, Mark A. Hull, Douglas J. Veale, Anne English, Alan Tennant, John D. Isaacs, CH Burgoyne, CA Lawson, Frederique Ponchel, Andrew K. Brown, R J Verburg, S L Bingham, P.G. Conaghan, P J Hamlin, Paul Emery, Ursula Fearon, J.M. van Laar, Elizabeth M A Hensor
Publikováno v: Annals of the rheumatic diseases. 67(6)
An abnormal CD4+ T cell subset related to inflammation exposure (inflammation-related cells, IRC) has been identified in rheumatoid arthritis (RA). Patients with inflammatory and non-inflammatory diseases were used to examine the relationship between
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b382321a40afa9171033606543a74c80
https://pubmed.ncbi.nlm.nih.gov/17644540
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5
[Untitled]
Autor: Poulam M. Patel, David Ma, Ann W. Morgan, Andrew Protheroe, Helen A. Papadaki, Sarah J. Bingham, Jacob M van Laar, Sarah L. Maltby, Ursula Fearon, Dennis McGonagle, John D. Isaacs, John A. Snowden, Maya H Buch, R J Verburg, Kath Short, Andrew K. Brown, Mark A. Quinn, Liz Straszynski, Douglas J. Veale, Aurelie Masurel, Frederique Ponchel, Alexander F. Markham, Paul Emery, Sarah L. Field, John Moore, CA Lawson, Susan H. Douglas
Publikováno v: Arthritis Research & Therapy. 7:R80
We previously demonstrated prolonged, profound CD4+ T-lymphopenia in rheumatoid arthritis (RA) patients following lymphocyte-depleting therapy. Poor reconstitution could result either from reduced de novo T-cell production through the thymus or from
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d5ff2cad41703ebae62128edfe97f49f
https://doi.org/10.1186/ar1452
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6
Phenotypical, Morphological and Molecular Analysis of Fresh Human Bone Marrow Mesenchymal/Stromal Stem Sells (MSCs) Enriched by Four Different Methods
Autor: Liz Straszynski, Sarah L. Field, Dennis McGonagle, Elena Jones, Frederique Ponchel, Paul Emery, Sally E. Kinsey
Publikováno v: Blood. 104:2337-2337
Methods have recently been described for purification of mesenchymal stem cells (MSCs) from human bone marrow (BM), based on different combinations of antibodies and magnetic beads (Quirici et al, 2002, Reyes et al, 2002, Jones et al, 2002, Gronthos
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::49102caf7e47c78372eff2ddc84fd4f9
https://doi.org/10.1182/blood.v104.11.2337.2337
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8
Akademický článek
Differential CpG DNA methylation in peripheral naïve CD4+ T-cells in early rheumatoid arthritis patients.
Autor: Pitaksalee, R.1 (AUTHOR), Burska, A. N.1 (AUTHOR), Ajaib, S.1 (AUTHOR), Rogers, J.1 (AUTHOR), Parmar, R.1 (AUTHOR), Mydlova, K.1 (AUTHOR), Xie, X.1 (AUTHOR), Droop, A.2 (AUTHOR), Nijjar, J. S.3 (AUTHOR), Chambers, P.1 (AUTHOR), Emery, P.1 (AUTHOR), Hodgett, R.4 (AUTHOR), McInnes, I. B.3 (AUTHOR), Ponchel, F.1 (AUTHOR) f.ponchel@leeds.ac.uk
Publikováno v: Clinical Epigenetics. 4/7/2020, Vol. 12 Issue 1, p1-16. 16p.
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