Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Liz Min"'
Autor:
Xiao Hu, Zongzhi Z. Liu, Xinyue Chen, Vincent P. Schulz, Abhishek Kumar, Amaleah A. Hartman, Jason Weinstein, Jessica F. Johnston, Elisa C. Rodriguez, Anna E. Eastman, Jijun Cheng, Liz Min, Mei Zhong, Christopher Carroll, Patrick G. Gallagher, Jun Lu, Martin Schwartz, Megan C. King, Diane S. Krause, Shangqin Guo
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
MKL1 is a key transcriptional co-activator of actin cytoskeleton genes. Here the authors show that MKL1 activation in somatic cells reduces chromatin accessibility and hinders full reprogramming to pluripotency. Reduction of MKL1, disruption of actin
Externí odkaz:
https://doaj.org/article/39034a1a1b414222967219825619062a
Autor:
Martin A. Schwartz, Xiao Hu, Anna E. Eastman, Xinyue Chen, Jason S. Weinstein, Megan C. King, Elisa C. Rodriguez, Christopher W. Carroll, Liz Min, Mei Zhong, Zongzhi Liu, Patrick G. Gallagher, Shangqin Guo, Jijun Cheng, Jun Lu, Abhishek Kumar, Jessica F. Johnston, Amaleah A. Hartman, Vincent P. Schulz, Diane S. Krause
Publikováno v:
Nature Communications
Hu, X, Liu, Z Z, Chen, X, Schulz, V P, Kumar, A, Hartman, A A, Weinstein, J, Johnston, J F, Rodriguez, E C, Eastman, A E, Cheng, J, Min, L, Zhong, M, Carroll, C, Gallagher, P G, Lu, J, Schwartz, M, King, M C, Krause, D S & Guo, S 2019, ' MKL1-actin pathway restricts chromatin accessibility and prevents mature pluripotency activation ', Nature Communications, vol. 10, no. 1, 1695 . https://doi.org/10.1038/s41467-019-09636-6
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Hu, X, Liu, Z Z, Chen, X, Schulz, V P, Kumar, A, Hartman, A A, Weinstein, J, Johnston, J F, Rodriguez, E C, Eastman, A E, Cheng, J, Min, L, Zhong, M, Carroll, C, Gallagher, P G, Lu, J, Schwartz, M, King, M C, Krause, D S & Guo, S 2019, ' MKL1-actin pathway restricts chromatin accessibility and prevents mature pluripotency activation ', Nature Communications, vol. 10, no. 1, 1695 . https://doi.org/10.1038/s41467-019-09636-6
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Actin cytoskeleton is well-known for providing structural/mechanical support, but whether and how it regulates chromatin and cell fate reprogramming is far less clear. Here, we report that MKL1, the key transcriptional co-activator of many actin cyto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c6fa88ee3a24806839b2d36622ff574
https://doi.org/10.1038/s41467-019-09636-6
https://doi.org/10.1038/s41467-019-09636-6