Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Liz Hernandez"'
Autor:
Alexander G. Raufi, Nicholas R. Liguori, Lindsey Carlsen, Cassandra Parker, Liz Hernandez Borrero, Shengliang Zhang, Xiaobing Tian, Anna Louie, Lanlan Zhou, Attila A. Seyhan, Wafik S. El-Deiry
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive disease characterized by early metastasis, late detection, and poor prognosis. Progress towards effective therapy has been slow despite significant efforts. Novel treatment approaches are despe
Externí odkaz:
https://doaj.org/article/9e013afab8844e3382a6ba0292407a29
Autor:
Xiaobing Tian, Shengliang Zhang, Lanlan Zhou, Attila A. Seyhan, Liz Hernandez Borrero, Yiqun Zhang, Wafik S. El-Deiry
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
The integrated stress response (ISR) is an evolutionarily conserved intra-cellular signaling network which is activated in response to intrinsic and extrinsic stresses. Various stresses are sensed by four specialized kinases, PKR-like ER kinase (PERK
Externí odkaz:
https://doaj.org/article/5e087687999b4cd98624127086ec17cb
Autor:
Liz Hernandez Borrero, David T Dicker, John Santiago, Jennifer Sanders, Xiaobing Tian, Nagib Ahsan, Avital Lev, Lanlan Zhou, Wafik S El-Deiry
Publikováno v:
eLife, Vol 10 (2021)
Mutations in TP53 occur commonly in the majority of human tumors and confer aggressive tumor phenotypes, including metastasis and therapy resistance. CB002 and structural-analogs restore p53 signaling in tumors with mutant-p53 but we find that unlike
Externí odkaz:
https://doaj.org/article/9c1569a9e1944110b2016496e39309bd
Autor:
Shengliang Zhang, Lindsey Carlsen, Liz Hernandez Borrero, Attila A. Seyhan, Xiaobing Tian, Wafik S. El-Deiry
Publikováno v:
Biomolecules, Vol 12, Iss 4, p 548 (2022)
TP53 is a tumor suppressor gene that encodes a sequence-specific DNA-binding transcription factor activated by stressful stimuli; it upregulates target genes involved in growth suppression, cell death, DNA repair, metabolism, among others. TP53 is th
Externí odkaz:
https://doaj.org/article/82791e06ae89482f9f11405588df6eee
Autor:
Jaya Kumari Swain, Yamila Carpio, Lill-Heidi Johansen, Janet Velazquez, Liz Hernandez, Yeny Leal, Ajey Kumar, Mario Pablo Estrada
Publikováno v:
PLoS ONE, Vol 15, Iss 10, p e0239827 (2020)
Infection with parasitic copepod salmon louse Lepeophtheirus salmonis, represents one of the most important limitations to sustainable Atlantic salmon (Salmo salar L.) farming today in the North Atlantic region. The parasite exerts negative impact on
Externí odkaz:
https://doaj.org/article/c054825d2aa249f8bcb1e3e6754d4cec
Publikováno v:
Stem Cells International, Vol 2016 (2016)
Genetic manipulation is a powerful tool to establish the causal relationship between a genetic lesion and a particular pathological phenotype. The rise of CRISPR/Cas9 genome-engineering tools overcame the traditional technical bottleneck for routine
Externí odkaz:
https://doaj.org/article/3fdb7d42d946439d8881a76a41e72ff3
Publikováno v:
F1000Research, Vol 3 (2014)
Breast cancer is the most commonly diagnosed cancer in women. The latest world cancer statistics calculated by the International Agency for Research on Cancer (IARC) revealed that 1,677,000 women were diagnosed with breast cancer in 2012 and 577,000
Externí odkaz:
https://doaj.org/article/db8707fe34194fd69d4c5dd15b8172ee
Akademický článek
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Autor:
Rebeca Martínez, Antonio Morales, Osmany Rodrigo, Liz Hernandez, Mario Pablo Estrada, Soraya Piloto, Liliana Basabe, Adriana Nuñez-Robainas, Janet Velázquez, Fidel Herrera, Daniel O Palenzuela, Adrian Rodriguez-Gabilondo, Hanlet Camacho
Publikováno v:
Fish & Shellfish Immunology. 119:508-515
Growth Hormone-Releasing Peptide 6 (GHRP-6) (His-(D-Trp)-Ala-Trp-(D-Phe)-Lys-NH2) is an agonist of the growth hormone secretagogue receptor. GHRP-6 mimics the effect of ghrelin. The present study focuses on the immunomodulatory effects of GHRP-6 in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c8d46b19e23175d92b0e0c05111135e
https://doi.org/10.1016/j.fsi.2021.08.011
https://doi.org/10.1016/j.fsi.2021.08.011
Autor:
Elisa Tomat, Rohit Kumar Sharma, Nahiara Alicea, Sofia C. Pérez Otero, Martin Kowaleff, Liz Hernandez-Matias, Eman A. Akam, Andrei V. Astashkin, Kavita Gaur, Sergio A. Loza-Rosas, Josué A. Benjamín-Rivera, Arthur D. Tinoco, Anthony V Washington, Alexandra M. Vázquez Salgado, Israel Rodríguez
Publikováno v:
JACS Au, Vol 1, Iss 6, Pp 865-878 (2021)
Jacs Au
Jacs Au
Efforts directed at curtailing the bioavailability of intracellular iron could lead to the development of broad-spectrum anticancer drugs given the metal’s role in cancer proliferation and metastasis. Human ribonucleotide reductase (RNR), the key e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10db648cb2073e34128f051b0b72e28e
https://doi.org/10.1021/jacsau.1c00078
https://doi.org/10.1021/jacsau.1c00078