Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Liz Bogaert"'
Autor:
Rajbharan Yadav, Suzanne Schubbert, Patrick G. Holder, Eugene Y. Chiang, Nargess Kiabi, Liz Bogaert, Irene Leung, Rumana Rashid, Kendra N. Avery, Christine Bonzon, John R. Desjarlais, Shomyseh Sanjabi, Amy Sharma, Michelle Lepherd, Amy Shelton, Pam Chan, Yanqiu Liu, Louis Joslyn, Iraj Hosseini, Eric G. Stefanich, Amrita V. Kamath, Matthew J. Bernett, Vittal Shivva
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
IntroductionInterleukin 15 (IL-15) is a potential anticancer agent and numerous engineered IL-15 agonists are currently under clinical investigation. Selective targeting of IL-15 to specific lymphocytes may enhance therapeutic effects while helping t
Externí odkaz:
https://doaj.org/article/31030b79b4034614806d2f9e04a075ba
Autor:
Marcin Kowanetz, Shelley Ackerman, David Dornan, Michael Alonso, Edith Perez, Cecelia Pearson, Arthur Lee, Karla Henning, Steven Chapin, LIsa Blum, Angela Luo, Matthew Zhou, Brian Safina, Amreen Husain, William Mallet, Rishali Gadkari, Laughing Bear Torrez Dulgeroff, AAngela Luondrew Luo, Jennifer Melrose, Jess Nolin, Puneet Anand, Ganapathy Sarma, Liz Bogaert, Romas Kudirka, Yuyi Shen
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/fb2042523bb947d7be8150b8d9c85ab4
Autor:
Mélanie Desbois, Thierry Giffon, Poonam Yakkundi, Sivani Pandey, Rodnie Rosete, Daniel Machado, Marigold Manlusoc, Susan Calhoun, Tasnim Kothambawala, Jey Ananta, Kristina Koyama, Yuan Cao, Dean Ng, Tomas Miranda-Katz, Avneesh Saini, Abhinav Jain, Hongjun Yue, Yang Cai, Miho Oyasu, Liz Bogaert, Roel Funke, Genevive Hernandez, Denise Nagata, Maya Leabman, Eric Humke, Stephen Carroll, Beatrice Wang, Bruce Keyt, Angus Sinclair, Maya Kotturi
Publikováno v:
Regular and Young Investigator Award Abstracts.
Autor:
Dan Lu, Rajbharan Yadav, Patrick Holder, Eugene Chiang, Shomyseh Sanjabi, Victor Poon, Matthew Bernett, Rajat Varma, Ke Liu, Irene Leung, Liz Bogaert, John Desjarlais, Vittal Shivva, Iraj Hosseini, Saroja Ramanujan
Publikováno v:
European Journal of Pharmaceutical Sciences. 186:106450
Autor:
Liqin Liu, Gene Li, Ling Wang, Poonam Yakkundi, Paul R. Hinton, Deepal Pandya, Manal Amoury, Keerthana Sekar, Chian Liu, Rodnie Rosete, Nardeen Hanna, Maya F. Kotturi, Liz Bogaert, Jiyoung Hong, Christina Tsai, Bruce A. Keyt, Angus M. Sinclair
Publikováno v:
Blood. 140:5918-5919
Autor:
Gene Li, Ling Wang, Poonam Yakkundi, Paul Hinton, Deepal Pandya, Keerthana Sekar, Rodine Rosete, Zhongde Ye, Nardeen Hanna, Maya F. Kotturi, Liz Bogaert, Jiyoung Hong, Christina Tsai, Thomas Manley, Bruce A. Keyt, Angus M. Sinclair, Liqin Liu
Publikováno v:
Cancer Research. 83:2933-2933
Novel therapeutics are needed for the effective treatment of acute myeloid leukemia (AML), as standard chemotherapeutics are poorly tolerated and ~50% of patients relapse primarily due to the incomplete elimination of leukemia stem cells (LSCs). CD12
Autor:
Karla Henning, Yuyi Shen, Jennifer Melrose, David Dornan, AAngela Luondrew Luo, Rishali Gadkari, Michael N. Alonso, Laughing Bear Torrez Dulgeroff, Jess Nolin, Cecelia Pearson, Ganapathy Sarma, Brian Safina, Edith A. Perez, Shelley Erin Ackerman, Liz Bogaert, Arthur Lee, Romas Kudirka, William Mallet, Lisa Blum, Puneet Anand, Angela Luo, Amreen Husain, Steven J. Chapin, Marcin Kowanetz, Matthew Zhou
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundCEA (CEACAM5) is a well-validated cell-surface antigen that is highly expressed in multiple solid tumors. Bolt's immune-stimulating antibody conjugates (ISACs) direct a TLR7/8 agonist into tumors to activate tumor-infiltrating myeloid cells
Autor:
Rishali Gadkari, Puneet Anand, Shelley Erin Ackerman, Jennifer Melrose, Romas Kudirka, Karla Henning, Ganapathy Sarma, Steven J. Chapin, Matthew Zhou, Arthur Lee, Suprit Deol, Cindy Kreder, Justin A. Kenkel, David Dornan, Marcin Kowanetz, William Mallet, Michael N. Alonso, Brian Safina, Liz Bogaert, Po Ho, Hai Li, Yuyi Shen
Publikováno v:
Journal for ImmunoTherapy of Cancer. 9:A817-A817
BackgroundPD-L1 is an immune checkpoint that regulates anti-tumor T cell responses and is expressed on tumor cells as well as tumor-infiltrating immune cells across many tumor types. Immune-stimulating antibody conjugates (ISACs) consist of tumor-tar
Autor:
Nicole Rodriguez, Gregory L. Moore, Connie Ardila, Seung Y. Chu, Sung-Hyung Lee, Alex Nisthal, Umesh Muchhal, Christine Bonzon, Rumana Rashid, Kendra N. Avery, Yoon Kyung Kim, John R. Desjarlais, Liz Bogaert, Irene W. Leung
Publikováno v:
Cancer Research. 80:2286-2286
Bispecific T cell engagers simultaneously bind CD3 on T cells and tumor-associated antigens to promote T cell-mediated killing of tumor cells. While targeting lineage-restricted antigens such as CD19 or CD20 have found clinical success in hematopoiet
Autor:
John R. Desjarlais, Ke Liu, Rumana Rashid, Liz Bogaert, Kendra N. Avery, Irene Leung, Suzanne Schubbert, Matthew J. Bernett, Christine Bonzon, Rajat Varma
Publikováno v:
Blood. 132:3709-3709
Regulatory T cells (Tregs) characterized as CD4 positive cells, expressing CD25 (IL-2Rα) and the forkhead transcription factor FoxP3 maintain immune tolerance in tissues by suppressing the function of both CD4 and CD8 effector T cells. It is well do