Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Liyang Fei"'
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
CCR2 is predominantly expressed by monocytes/macrophages with strong proinflammatory functions, prompting the development of CCR2 antagonists to dampen unwanted immune responses in inflammatory and autoimmune diseases. Paradoxically, CCR2-expressing
Externí odkaz:
https://doaj.org/article/44f816e4bb85407aa777748024a06291
Autor:
Xiaopei Cui, Xi Zhu, Haijia Yu, Jingen Xu, Xiaoyue Wei, Shi Chen, Yangtin Wang, Xiaofang Chen, Yujie Feng, Xiaochen Ren, Liyang Fei, Bin Xie, Mingwei Li, Xue Li, Huifeng Jia, Simin Xie, Li Chen, Yong Cheng, Lei Zhang, Haidong Li, Xiangyang Zhu, Yifan Zhan
Co-targeting PD-1/PD-L1 and TIGIT/CD226 is being pursued to broaden the efficacy of current immunotherapy. Here we demonstrate that a bispecific antibody (BsAb) targeting PD-L1 and TIGIT, HB0036, shows major advantages over the combination of the two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa4b517a26989fbd8310939cc91c4003
https://doi.org/10.1101/2023.05.11.540461
https://doi.org/10.1101/2023.05.11.540461