Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Liya Y. Qiao"'
Publikováno v:
Cell Reports, Vol 43, Iss 5, Pp 114230- (2024)
Summary: Satellite glial cells (SGCs) of dorsal root ganglia (DRGs) are activated in a variety of chronic pain conditions; however, their mediation roles in pain remain elusive. Here, we take advantage of proteolipid protein (PLP)/creERT-driven recom
Externí odkaz:
https://doaj.org/article/921e33d88fff4e81b17c2ff0804d6ff8
Autor:
Jonathan Madar, Namrata Tiwari, Cristina Smith, Divya Sharma, Shanwei Shen, Alsiddig Elmahdi, Liya Y. Qiao
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract The mechanosensitive ion channel Piezo2 in mucosa and primary afferents transduces colonic mechanical sensation. Here we show that chemogenetic activation or nociceptor-targeted deletion of Piezo2 is sufficient to regulate colonic mechanical
Externí odkaz:
https://doaj.org/article/28a4abfc47fb4adaae40700d2f1dff62
Autor:
Namrata Tiwari, Liya Y. Qiao
Publikováno v:
Cells, Vol 13, Iss 10, p 834 (2024)
Sexual dimorphism of visceral pain has been documented in clinics and experimental animal models. Aside from hormones, emerging evidence suggests the sex-differential intrinsic neural regulation of pain generation and maintenance. According to the In
Externí odkaz:
https://doaj.org/article/97ab2b65c7e4499989d45fc840e76388
Autor:
Liya Y Qiao, Jonathan Madar
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0245410 (2021)
The present study presents a non-surgical approach to assess colonic mechanical sensitivity in mice using colonometry, a technique in which colonic stretch-reflex contractions are measured by recording intracolonic pressures during saline infusion in
Externí odkaz:
https://doaj.org/article/6ce67d2bdca740db98ef131eb2378a8a
Publikováno v:
Pain
Sympathoneuronal outflow into dorsal root ganglia (DRG) is suggested to be involved in sympathetically maintained chronic pain, which is mediated by norepinephrine (NE) action on DRG cells. This study combined in vitro and in vivo approaches to ident
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb86e3869034d8cb62c5eb1fa469c30c
https://doi.org/10.1097/j.pain.0000000000002330
https://doi.org/10.1097/j.pain.0000000000002330
Autor:
Salvador Sierra, Karan H. Muchhala, Donald K. Jessup, Katherine M. Contreras, Urjita H. Shah, David L. Stevens, Jennifer Jimenez, Xiomara K. Cuno Lavilla, Mario de la Fuente Revenga, Kumiko M. Lippold, Shanwei Shen, Justin L. Poklis, Liya Y. Qiao, William L. Dewey, Hamid I. Akbarali, M. Imad Damaj, Javier González-Maeso
Publikováno v:
Neuropharmacology
Opioids are among the most effective analgesics and the mainstay of pain management. However, concerns about safety and abuse liability have challenged their widespread use by the medical community. Opioid-sparing therapies include drugs that in comb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95feeb11babd86469a7334f6aa4413de
https://europepmc.org/articles/PMC8934299/
https://europepmc.org/articles/PMC8934299/
Autor:
Liya Y. Qiao, Namrata Tiwari
Publikováno v:
Am J Physiol Gastrointest Liver Physiol
Inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS), historically considered as regional gastrointestinal disorders with heightened colonic sensitivity, are increasingly recognized to have concurrent dysfunction of other visceral and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad7c07bac567e15c9c50fb7c6f8bd996
https://europepmc.org/articles/PMC7792669/
https://europepmc.org/articles/PMC7792669/
Autor:
Jonathan Madar, Liya Y Qiao
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0245410 (2021)
PLoS ONE
PLoS ONE
The present study presents a non-surgical approach to assess colonic mechanical sensitivity in mice using colonometry, a technique in which colonic stretch-reflex contractions are measured by recording intracolonic pressures during saline infusion in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adf584d8881493d34852f15829f93d69
https://doi.org/10.1371/journal.pone.0245410
https://doi.org/10.1371/journal.pone.0245410