Zobrazeno 1 - 10
of 665
pro vyhledávání: '"Lixin MA"'
Autor:
Ying Xu, Wen Yin, Yibin Cheng, Wei Zeng, Wenqiang Li, Wanping Chen, Fei Wang, Nan Peng, Lixin Ma, Tao Liu
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-8 (2024)
Abstract TnpB proteins encoded in the IS200/IS605 family are RNA-guided endonuclease which can be harnessed in genome editing. However, the collateral nuclease activity of TnpB remains poorly understood, which limits the development of TnpB-based dia
Externí odkaz:
https://doaj.org/article/c1a0f86a45bc4812bb754522d200309b
Autor:
Weihai Ning, Xiao Qian, Louisa Chard Dunmall, Funan Liu, Yuduo Guo, Shenglun Li, Dixiang Song, Deshan Liu, Lixin Ma, Yanming Qu, Haoran Wang, Chunyu Gu, Mingshan Zhang, Yaohe Wang, Shengdian Wang, Hongwei Zhang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Malignant glioma is a highly fatal central nervous system malignancy with high recurrence rates. Oncolytic viruses offer potential treatment but need improvement in efficacy and safety. Here we describe a phase I, dose-escalating, single arm
Externí odkaz:
https://doaj.org/article/dc2220237c314540a478ed57334e9ea9
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
Insect cytochrome P450 monooxygenases (CYPs) play crucial roles in the metabolic detoxification of insecticides. Ethyl formate and benzothiazole have recently regained popularity as fumigants due to rising resistance to phosphine in the stored-produc
Externí odkaz:
https://doaj.org/article/303526de7a4a41baaa0a27012c51291c
Autor:
Mingjun Yang, Xianhui Su, Jun Yang, Zhiwen Lu, Jie Zhou, Fei Wang, Yang Liu, Lixin Ma, Chao Zhai
Publikováno v:
Microbial Cell Factories, Vol 23, Iss 1, Pp 1-13 (2024)
Abstract Background Rhizomucor miehei (RM) lipase is a regioselective lipase widely used in food, pharmaceutical and biofuel industries. However, the high cost and low purity of the commercial RM lipase limit its industrial applications. Therefore, i
Externí odkaz:
https://doaj.org/article/e4ff92097203415c88c5d0c02902ebd8
Autor:
Amy N. Keilholz, Ishan Pathak, Catherine L. Smith, Kate L. Osman, Lauren Smith, Grace Oti, Mojgan Golzy, Lixin Ma, Teresa E. Lever, Nicole L. Nichols
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
IntroductionTongue weakness and atrophy can lead to deficits in the vital functions of breathing and swallowing in patients with motor neuron diseases (MNDs; e.g., amyotrophic lateral sclerosis (ALS) and pseudobulbar palsy), often resulting in aspira
Externí odkaz:
https://doaj.org/article/bd704596fda541c590c6727ea41c2f81
Autor:
Kailong Xu, Jiang Li, LiWei Qin, Jie Liu, Heng Yang, Gang Dou, LiXin Ma, Yanming Dong, Yang Wang
Publikováno v:
Heliyon, Vol 10, Iss 13, Pp e33196- (2024)
Background: Renal cell carcinoma (RCC) is characterized by its heterogeneity and the complexity of its tumor microenvironment. This study addresses the need to understand RCC at a cellular level, with a focus on its three main subtypes: clear cell (c
Externí odkaz:
https://doaj.org/article/b1996e4decaa4f4a8771a1497a626eb5
Autor:
Fei Shi, Zhilong Chen, Minshan Yao, Yao Huang, Jin Xiao, Lixin Ma, Jilin Mo, Li Lin, Zhendong Qin
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 272, Iss , Pp 116078- (2024)
Since disinfectants are used all over the world to treat illnesses in people and other animals, they pose a major risk to human health. The comprehensive effects of disinfectant treatments on fish liver, especially the impacts on oxidative stress, to
Externí odkaz:
https://doaj.org/article/9200a6223cc944a1891168e2d8306cfc
Autor:
Hang Xu, Ping Yu, Rajendra P. Bandari, Charles J. Smith, Michael R. Aro, Amolak Singh, Lixin Ma
Publikováno v:
Nanomaterials, Vol 14, Iss 14, p 1177 (2024)
We developed a novel site-specific bimodal MRI/fluorescence nanoparticle contrast agent targeting gastrin-releasing peptide receptors (GRPrs), which are overexpressed in aggressive prostate cancers. Biocompatible ultra-small superparamagnetic iron ox
Externí odkaz:
https://doaj.org/article/ad6ff45980e44c6e98a4f22cf155c7b6
Publikováno v:
Biosensors, Vol 14, Iss 5, p 245 (2024)
Since SARS-CoV-2 is a highly transmissible virus, alternative reliable, fast, and cost-effective methods are still needed to prevent virus spread that can be applied in the laboratory and for point-of-care testing. Reverse transcription real-time flu
Externí odkaz:
https://doaj.org/article/5591fe7d63a747e4b0205946d831def7
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108340- (2023)
Summary: Sorafenib induces ferroptosis, making it a useful treatment against advanced liver hepatocellular carcinoma (LIHC). However, sorafenib resistance is extremely common among LIHC patients. Here, we used a comprehensive approach to investigate
Externí odkaz:
https://doaj.org/article/c9be4899148042c19f1f37dad2314c3a