Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Lixiao Che"'
Autor:
Lixiao Che, Xingyuan Yang, Chunmin Ge, Salim S El-Amouri, Qi-En Wang, Dao Pan, Thomas J Herzog, Chunying Du
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0216553 (2019)
Autophagy is an intracellular catabolic system. It delivers cellular components to lysosomes for degradation and supplies nutrients that promote cell survival under stress conditions. Although much is known regarding starvation-induced autophagy, the
Externí odkaz:
https://doaj.org/article/3a95895e3a0f4d83bea9037b19e82b2f
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0144957 (2015)
BRUCE is implicated in the regulation of DNA double-strand break response to preserve genome stability. It acts as a scaffold to tether USP8 and BRIT1, together they form a nuclear BRUCE-USP8-BRIT1 complex, where BRUCE holds K63-ubiquitinated BRIT1 f
Externí odkaz:
https://doaj.org/article/f1653f9d54934271b395904ffe4f6dfd
Autor:
Lixiao Che, Kejian Wang, Ding Tang, Qiaoquan Liu, Xiaojun Chen, Yafei Li, Qing Hu, Yi Shen, Hengxiu Yu, Minghong Gu, Zhukuan Cheng
Publikováno v:
PLoS Genetics, Vol 10, Iss 6, p e1004405 (2014)
Meiotic recombination normally takes place between allelic sequences on homologs. This process can also occur between non-allelic homologous sequences. Such ectopic interaction events can lead to chromosome rearrangements and are normally avoided. Ho
Externí odkaz:
https://doaj.org/article/6e120b1e7bcd4177ad49b497aba7ff21
Autor:
Arun Pradhan, Lixiao Che, Vladimir Ustiyan, Abid A. Reza, Nicole M. Pek, Yufang Zhang, Andrea B. Alber, Timothy R. Kalin, Jennifer A. Wambach, Mingxia Gu, Darrell N. Kotton, Matthew E. Siefert, Assem G. Ziady, Tanya V. Kalin, Vladimir V. Kalinichenko
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 207:1042-1054
Alveolar Capillary Dysplasia with Misalignment of Pulmonary Veins (ACDMPV) is linked to heterozygous mutations in the FOXF1 gene, a key transcriptional regulator of pulmonary vascular development. There are no effective treatments for ACDMPV other th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e84e62a57a4b9ba7085d590bd8aeac1f
https://doi.org/10.1164/rccm.202207-1332oc
https://doi.org/10.1164/rccm.202207-1332oc
Autor:
Xing Wang, Yuanyuan Liu, Qiuyan Zhao, Xin Wang, Xinyi Chen, Li Hou, Shaodan Tian, Zi-Mei Peng, Xiao-Jian Han, Tao Wang, Zhen Zhang, Fang-Fang Tou, Shan Huang, Jun Rao, Lixiao Chen, Zhi Zheng
Publikováno v:
Cell Death and Disease, Vol 15, Iss 9, Pp 1-15 (2024)
Abstract Paired immunoglobin-like type 2 receptor beta (PILRB) mainly plays a crucial role in regulating innate immunity, but whether PILRB is involved in cancer is poorly understood. Here, we report that PILRB potentiates the PI3K/AKT pathway to dri
Externí odkaz:
https://doaj.org/article/8e34be5d33e647fc9a572d2cdea46c5e
Autor:
Chunying Du, Shimul A. Shah, Chrystelle L. Vilfranc, Olugbenga Olowokure, Liang Niu, Lixiao Che, Krushna C. Patra, Jiang Wang
Publikováno v:
World Journal of Hepatology
Background BIR repeat-containing ubiquitin conjugating enzyme (BRUCE) is a liver tumor suppressor, which is downregulated in a large number of patients with liver diseases. BRUCE facilitates DNA damage repair to protect the mouse liver against the he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::626c02d420800d02c5f4485b761a4d02
https://doi.org/10.4254/wjh.v13.i3.343
https://doi.org/10.4254/wjh.v13.i3.343
Novel FOXF1-Stabilizing Compound TanFe Stimulates Lung Angiogenesis in Alveolar Capillary Dysplasia.
Autor:
Pradhan, Arun, Lixiao Che, Ustiyan, Vladimir, Reza, Abid A., Pek, Nicole M., Yufang Zhang, Alber, Andrea B., Kalin, Timothy R., Wambach, Jennifer A., Mingxia Gu, Kotton, Darrell N., Siefert, Matthew E., Ziady, Assem G., Kalin, Tanya V., Kalinichenko, Vladimir V.
Publikováno v:
American Journal of Respiratory & Critical Care Medicine; 4/15/2023, Vol. 207 Issue 8, p1042-1054, 13p
Autor:
Shuang Wang, Hengjie Xie, Lu Liu, Lei Du, Fang Yin, Yuzhen Chen, Ziqing Liu, Gaoxiang Sun, Xiaomei Zhang, Dapeng Sun, Ming Fang, Lixiao Cheng, Yanru Chen, Zengqiang Kou, Beiwen Zheng
Publikováno v:
Emerging Microbes and Infections, Vol 13, Iss 1 (2024)
Bacillus paranthracis, a Gram-positive conditional pathogen of Bacillus cereus group species, is capable of causing foodborne and waterborne illnesses, leading to intestinal diseases in humans characterized by diarrhoea and vomiting. However, documen
Externí odkaz:
https://doaj.org/article/de17d34d030b4f219fa7fc230fbec0a0
Publikováno v:
Cell death and differentiation, vol 27, iss 8
Cell Death Differ
Cell Death Differ
BRUCE is a DNA damage response protein that promotes the activation of ATM and ATR for homologous recombination (HR) repair in somatic cells, making BRUCE a key protector of genomic stability. Preservation of genomic stability in the germline is esse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fef6f38c273119d05bf972fb96a73bbc
https://escholarship.org/uc/item/5xc3t4s1
https://escholarship.org/uc/item/5xc3t4s1
Autor:
Yuanyuan Liu, Xing Wang, Yuying Liu, Jianqiang Yang, Wei Mao, Chen Feng, Xiaoliang Wu, Xinwei Chen, Lixiao Chen, Pin Dong
Publikováno v:
Cell Death and Disease, Vol 14, Iss 11, Pp 1-15 (2023)
Abstract N4-acetylcytidine (ac4C) is a post-transcriptional RNA modification that regulates in various important biological processes. However, its role in human cancer, especially lymph node metastasis, remains largely unknown. Here, we demonstrated
Externí odkaz:
https://doaj.org/article/4520f525726c411e866cb6e99ebc7747