Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Lixian Gan"'
Publikováno v:
Chinese Journal of Physiology, Vol 66, Iss 4, Pp 220-227 (2023)
Lijie Capsules (LJJN) are a classical Chinese herbal formula adopted to treat rheumatoid arthritis (RA) clinically, yet the regulatory mechanism underlying the protection of LJJN against RA has not been fully elucidated. Here, the animal model of RA
Externí odkaz:
https://doaj.org/article/560e7258456b4a5abdc47d06088d2092
Autor:
Beth B. Pinney, Jeffery C. Hayes, Xinrong Tian, Russell James Sheldon, Mark Gregory Solinsky, Adrian Gregory Switzer, Frank H. Ebetino, Doreen Crossdoersen, John August Wos, Julie A. Farmer, Xuemei Chen, Lixian Gan
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 16:1721-1725
The first synthesis of Tic-D-Phe Psi[CH(2)-CH(2)] isostere is described, which features diastereoselective alkylation of the tricyclic lactam 14. The use of this novel dipeptide isostere in the development of melanocortin agonists has been demonstrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29f2e272b4df8d3a15260f691f187f61
https://doi.org/10.1016/j.bmcl.2005.12.005
https://doi.org/10.1016/j.bmcl.2005.12.005
Autor:
J. Chen, I. J. Magrisso, S. A. Green, J. M. Ridgeway, D. E. Kellstein, Lixian Gan, L. I. Wu, Debra L. Kuhlenbeck, P. A. Young, John Michael Janusz, Thomas H. Eichhold, Michael Wiard Scherz, K. Enzweiler, J. L. Tulich, Roy L. M. Dobson, T. Rosario-Jansen, Kenneth R. Wehmeyer
Publikováno v:
Journal of Medicinal Chemistry. 41:3515-3529
We report an expansion of the scope of our initial discovery that 5-keto-substituted 7-tert-butyl-2,3-dihydro-3,3-dimethylbenzofurans (DHDMBFs) are antiinflammatory and analgesic agents. Several other functional groups have been introduced at the 5 p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d39a59e70a7dacc34d27976abd5fc60
https://doi.org/10.1021/jm9802416
https://doi.org/10.1021/jm9802416
Autor:
Paul A. Seib, Lixian Gan
Publikováno v:
Journal of Carbohydrate Chemistry. 17:397-404
Esterification of L-ascorbic acid in concentrated sulfuric acid with 0.33 moles of gallic acid gave a 90% yield of a 2:5 mixture of L-ascorbyl 5- and 6-gallate esters. The 6-gallate ester (1) was purified from the 5-gallate ester (2) by fractional cr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::143cad0c7a931c2c770111206da4020d
https://doi.org/10.1080/07328309808002901
https://doi.org/10.1080/07328309808002901
Autor:
K. L. Mcdow-Dunham, I. J. Magrisso, K. R. Wehmeyer, S. Pikul, L. I. Wu, C. B. Senanayake, D. L. Kuhlenbeck, T. H. Eichhold, P. A. Young, J. L. Tulich, R. L. M. Dobson, S. A. Green, Lixian Gan, D. E. Kellstein, T. Rosario-Jansen, John Michael Janusz, M. W. Scherz, K. Enzweiler, Carl R. Johnson
Publikováno v:
Journal of Medicinal Chemistry. 41:1124-1137
A series of 5-keto-substituted 7-tert-buty1-2,3-dihydro-3,3- dimethylbenzofurans (DHDMBFs) were found to be nonsteroidal antiinflammatory and analgesic agents. These compounds are inhibitors of 5-lipoxygenase (5-LOX) and cyclooxygenase (COX) with sel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85a8e1d861641d90ffe2e4ad41e8dd74
https://doi.org/10.1021/jm970680p
https://doi.org/10.1021/jm970680p
Autor:
T. Rosario-Jansen, Roy L. M. Dobson, L. I. Wu, Michael Wiard Scherz, D. E. Kellstein, Kenneth R. Wehmeyer, J. M. Ridgeway, Randall Stryker Matthews, Lixian Gan, I. J. Magrisso, Debra L. Kuhlenbeck, D. Hennes, P. A. Young, K. Enzweiler, J. L. Tulich, R. Darolia, S. A. Green, Thomas H. Eichhold, John Michael Janusz, S. P. Sirko, R. W. Farmer
Publikováno v:
Journal of Medicinal Chemistry. 41:1112-1123
A series of 5-keto-substituted 7-tert-butyl-2,3-dihydro-3,3-dimethylbenzofurans (DHDMBFs) were prepared and evaluated as potential nonsteroidal antiinflammatory and analgesic agents. Interest in this class of compounds arose when a DHDMBF was found t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::254a622bfb286d235707509258e32aa6
https://doi.org/10.1021/jm970679q
https://doi.org/10.1021/jm970679q
Publikováno v:
Journal of Carbohydrate Chemistry. 16:155-164
Methyl 6-O-, 3-O- and 2-O-(2′-hydroxypropyl)-α-D-glucopyranosides (4,8, and 12) were synthesized starting from methyl 2,3,4-tri-O-benzyl-α-D-glucopyranoside (1), methyl 4,6-O-benzylidene-α-D-glucopyranoside (5), and methyl 3-O-benzyl-4,6-O-benzy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d862ac75a8a803a381f9c1e9b2759db0
https://doi.org/10.1080/07328309708006517
https://doi.org/10.1080/07328309708006517
Autor:
Paul A. Seib, Lixian Gan
Publikováno v:
ChemInform. 29
Esterification of L-ascorbic acid in concentrated sulfuric acid with 0.33 moles of gallic acid gave a 90% yield of a 2:5 mixture of L-ascorbyl 5- and 6-gallate esters. The 6-gallate ester (1) was purified from the 5-gallate ester (2) by fractional cr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff17d17a3f38439e265625918e761454
https://doi.org/10.1002/chin.199838246
https://doi.org/10.1002/chin.199838246
Autor:
Paul A. Seib, Lixian Gan
Publikováno v:
Carbohydrate Research. 220:117-125
Reaction of a 4:1 mixture of d -ribono- and d -arabinono-1,4-lactones with benzaldehyde and hydrochloric acid gave 59% crystalline 3,4- O -benzylidene- d -ribono-1,5-lactone. This acetal was oxidized with manganese dioxide in acetone to its 2-keto de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01ee8ab15c37405c8d3cd179d5e2a9a8
https://doi.org/10.1016/0008-6215(91)80010-k
https://doi.org/10.1016/0008-6215(91)80010-k
Autor:
John M. Janusz, Patricia A. Young, Michael W. Scherz, Kevin Enzweiler, Laurence I. Wu, Lixian Gan, Stanislaw Pikul, Kelly L. McDow-Dunham, Carl R. Johnson, C. B. Senanayake, David E. Kellstein, Shelley A. Green, Jennifer L. Tulich, Theresa Rosario-Jansen, I. Jack Magrisso, Kenneth R. Wehmeyer, Deborah L. Kuhlenbeck, Thomas H. Eichhold, Roy L. M. Dobson
Publikováno v:
Journal of Medicinal Chemistry. 41:3102-3102
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd4682d0f1c1c9b7f2e821d4bd9de5b1
https://doi.org/10.1021/jm980341b
https://doi.org/10.1021/jm980341b