Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Liwei Lang"'
Autor:
Vadym Buncha, Katie Anne Fopiano, Liwei Lang, Celestine Williams, Anatolij Horuzsko, Jessica Andrea Filosa, Gaston Kapuku, Zsolt Bagi
Publikováno v:
Physiological Reports, Vol 11, Iss 6, Pp n/a-n/a (2023)
Abstract Endothelial cell‐selective adhesion molecule (ESAM) regulates inflammatory cell adhesion and transmigration and promotes angiogenesis. Here, we examined the role of ESAM in cardiac vascularization, inflammatory cell infiltration, and left
Externí odkaz:
https://doaj.org/article/514d96ab2ffe4a84a50dcbd6f20cd596
Autor:
Yanna Tian, Katie Anne Fopiano, Vadym Buncha, Liwei Lang, Hayden A. Suggs, Rongrong Wang, R. Daniel Rudic, Jessica A. Filosa, Zsolt Bagi
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
IntroductionThe disintegrin and metalloproteinase 17 (ADAM17) exhibits α-secretase activity, whereby it can prevent the production of neurotoxic amyloid precursor protein-α (APP). ADAM17 is abundantly expressed in vascular endothelial cells and may
Externí odkaz:
https://doaj.org/article/e83ac162e11141978cac8661661d4819
Autor:
Liwei Lang, Reid Loveless, Juan Dou, Tiffany Lam, Alex Chen, Fang Wang, Li Sun, Jakeline Juarez, Zhaohui Steve Qin, Nabil F. Saba, Chloe Shay, Yong Teng
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-16 (2022)
Abstract Background Targeting mitochondrial oncoproteins presents a new concept in the development of effective cancer therapeutics. ATAD3A is a nuclear-encoded mitochondrial enzyme contributing to mitochondrial dynamics, cholesterol metabolism, and
Externí odkaz:
https://doaj.org/article/354761645dbd4b6a92f0dcb4b63e18b8
Autor:
Liwei Lang, Fang Wang, Zhichun Ding, Xiangdong Zhao, Reid Loveless, Jin Xie, Chloe Shay, Peng Qiu, Yonggang Ke, Nabil F. Saba, Yong Teng
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-14 (2021)
Abstract Background Alterations in metabolism are one of the emerging hallmarks of cancer cells and targeting dysregulated cancer metabolism provides a new approach to developing more selective therapeutics. However, insufficient blockade critical me
Externí odkaz:
https://doaj.org/article/eeac910264e948439b61a828e4cab76d
Autor:
Liwei Lang, Yuanping Xiong, Nestor Prieto-Dominguez, Reid Loveless, Caleb Jensen, Chloe Shay, Yong Teng
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-14 (2021)
Abstract Background There is no consensus about the effective dosages of melatonin in cancer management, thus, it is imperative to fully understand the dose-dependent responsiveness of cancer cells to melatonin and the underlying mechanisms. Methods
Externí odkaz:
https://doaj.org/article/6e0668c9c3b948c5ad78f147362b727d
Publikováno v:
Journal of Hematology & Oncology, Vol 12, Iss 1, Pp 1-14 (2019)
Abstract Background Src, an oncoprotein that drives progression of head and neck squamous cell carcinoma (HNSCC), is commonly hyperactivated in this disease. Unfortunately, the clinical benefit of targeting Src is significantly dampened in HNSCC pati
Externí odkaz:
https://doaj.org/article/4a560649bf20489eb4debd53cfcd460c
Autor:
Ruihua Dong, Hongyun Wang, Dandan Li, Liwei Lang, Frank Gray, Yongzhen Liu, Celine M. Laffont, Malcolm Young, Ji Jiang, Zeyuan Liu, Susan M. Learned
Publikováno v:
Drugs in R&D, Vol 19, Iss 3, Pp 255-265 (2019)
Abstract Background Two phase I studies assessed the pharmacokinetics of buprenorphine, its metabolite norbuprenorphine, and naloxone following administration of buprenorphine/naloxone sublingual tablets in Chinese participants. Methods In the first
Externí odkaz:
https://doaj.org/article/79bde2a917974800ab91d5b4112163f5
Autor:
Yuanping Xiong, Leilei He, Chloe Shay, Liwei Lang, Jenni Loveless, Jieqing Yu, Ron Chemmalakuzhy, Hongqun Jiang, Manran Liu, Yong Teng
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-11 (2019)
Abstract Background Metastatic lung cancer is a life-threatening condition that develops when cancer in another area of the body metastasizes, or spreads, to the lung. Despite advances in our understanding of primary lung oncogenesis, the biological
Externí odkaz:
https://doaj.org/article/16dd7cd7c3b54c54a90f72b5a78121ab
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-10 (2019)
Abstract Background A promising arsenal of histone deacetylase (HDAC)-targeted treatment has emerged in the past decade, as the abnormal targeting or retention of HDACs to DNA regulatory regions often occurs in many cancers. Head and neck squamous ce
Externí odkaz:
https://doaj.org/article/2433af4f091e4183a430ad123b3e3e51
Autor:
Liwei Lang, Chloe Shay, Yuanping Xiong, Parth Thakkar, Ron Chemmalakuzhy, Xuli Wang, Yong Teng
Publikováno v:
Journal of Hematology & Oncology, Vol 11, Iss 1, Pp 1-13 (2018)
Abstract Background Inhibition of metastasis of head and neck squamous cell carcinoma (HNSCC) is one of the most important challenges in cancer treatment. Src, a non-receptor tyrosine kinase, has been implicated as a key promoter in tumor progression
Externí odkaz:
https://doaj.org/article/e9e17289906d4324ad97c15efae67870