Zobrazeno 1 - 10
of 272
pro vyhledávání: '"Liwei Gu"'
Autor:
Shengnan Shen, Qiwen Liao, Liwei Gu, Yongping Zhu, Yanqing Liu, Xinwei Zhang, Junzhe Zhang, Qiaoli Shi, Yuxiang Sun, Jigang Wang, Ligen Lin
Publikováno v:
Acta Materia Medica, Vol 3, Iss 1, Pp 31-45 (2024)
G protein-coupled receptors (GPCRs) are important, potential drug targets for the treatment of metabolic disorders, such as obesity. GPCRs crosstalk with several transducers, including heterotrimeric G proteins, GPCR kinases (GRKs), and β-arrestins.
Externí odkaz:
https://doaj.org/article/ff691603cecd4052bd61b8b36d583a93
Autor:
Peng Gao, Jianyou Wang, Jiayun Chen, Liwei Gu, Chen Wang, Liting Xu, Yin Kwan Wong, Huimin Zhang, Chengchao Xu, Lingyun Dai, Jigang Wang
Publikováno v:
Engineering, Vol 31, Iss , Pp 86-97 (2023)
The widespread use of artemisinin (ART) and its derivatives has significantly reduced the global burden of malaria; however, malaria still poses a serious threat to global health. Although significant progress has been achieved in elucidating the ant
Externí odkaz:
https://doaj.org/article/b4d7d56ea69147d898cd881c039fd874
Autor:
Guanjun Li, Xueyan Liu, Xin Sun, Ling Huang, Wenhua Kuang, Jinhuan Ou, Junzhe Zhang, Ziyue Zhang, Huiying Li, Huan Tang, Chenran Feng, Liwei Gu, Chuanbin Yang, Wang Peili, Jigang Wang
Publikováno v:
Environment International, Vol 185, Iss , Pp 108543- (2024)
Exposure to environmentally hazardous substances is recognized as a significant risk factor for neurological associated disorders. Among these substances, polystyrene microplastics (PS-MPs), widely utilized in various consumer products, have been rep
Externí odkaz:
https://doaj.org/article/89b02feadfbe4ee8be04985d7d091572
Autor:
Jiayun Chen, Xueling He, Yunmeng Bai, Jing Liu, Yin Kwan Wong, Lulin Xie, Qian Zhang, Piao Luo, Peng Gao, Liwei Gu, Qiuyan Guo, Guangqing Cheng, Chen Wang, Jigang Wang
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 13, Iss 7, Pp 817-829 (2023)
Sepsis is characterized by a severe and life-threatening host immune response to polymicrobial infection accompanied by organ dysfunction. Studies on the therapeutic effect and mechanism of immunomodulatory drugs on the sepsis-induced hyperinflammato
Externí odkaz:
https://doaj.org/article/b9e0d873b1ba4bb3861585d5cc490e8a
Autor:
Yuqing Meng, Jiayun Chen, Yanqing Liu, Yongping Zhu, Yin-Kwan Wong, Haining Lyu, Qiaoli Shi, Fei Xia, Liwei Gu, Xinwei Zhang, Peng Gao, Huan Tang, Qiuyan Guo, Chong Qiu, Chengchao Xu, Xiao He, Junzhe Zhang, Jigang Wang
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 12, Iss 6, Pp 879-888 (2022)
The composition of serum is extremely complex, which complicates the discovery of new pharmacodynamic biomarkers via serum proteome for disease prediction and diagnosis. Recently, nanoparticles have been reported to efficiently reduce the proportion
Externí odkaz:
https://doaj.org/article/e4c8b83817224290a1b16557dbc499a8
Autor:
Liwei Gu, Jiaxing Zhang, Dandan Liu, Jiayun Chen, Shuzhi Liu, Qing Peng, Ya Tian, Maobo Du, Junzhe Zhang, Wei Xiao, Shuo Shen, Jigang Wang
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-21 (2022)
Abstract Breast cancer is the leading cause of cancer-related deaths in women and remains a formidable therapeutic challenge. Mitochondria participate in a myriad of essential cellular processes, such as metabolism, and are becoming an ideal target f
Externí odkaz:
https://doaj.org/article/a73e6af8ec254de6ae6e27692d651bfb
Autor:
Ya Tian, Zhongyuan Zheng, Xi Wang, Shuzhi Liu, Liwei Gu, Jing Mu, Xiaojun Zheng, Yujie Li, Shuo Shen
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-22 (2022)
Abstract Cerebral malaria (CM) is a life-threatening neurological complication caused by Plasmodium falciparum. About 627,000 patients died of malaria in 2020. Currently, artemisinin and its derivatives are the front-line drugs used for the treatment
Externí odkaz:
https://doaj.org/article/3f1ed315750343b49f1a6fd9743febf1
Autor:
Victor Cedeno-Sanchez, Melissa Perez-Santana, Devanshu Mehta, Scarlett Godinez, Liwei Gu, Victoria M. Miller, Andrew J. MacIntosh
Publikováno v:
Gels, Vol 9, Iss 10, p 798 (2023)
Standard Palm Oil (SPO) is widely used as a food ingredient partially due to its unique thermophysical properties. However, the American Heart Association recommends a saturated fat consumption of OxG Palm hybrid yields oil known as “palm oil with
Externí odkaz:
https://doaj.org/article/beaa0dd873fe483eb56877e8458854a4
Autor:
Chong Qiu, Fei Xia, Junzhe Zhang, Qiaoli Shi, Yuqing Meng, Chen Wang, Huanhuan Pang, Liwei Gu, Chengchao Xu, Qiuyan Guo, Jigang Wang
Publikováno v:
Research, Vol 6 (2023)
Nanocarriers have therapeutic potential to facilitate drug delivery, including biological agents, small-molecule drugs, and nucleic acids. However, their efficiency is limited by several factors; among which, endosomal/lysosomal degradation after end
Externí odkaz:
https://doaj.org/article/aae7928c8d5e4597ac04055a2db23fd9
Autor:
Dan-Dan Liu, Piao Luo, Liwei Gu, Qian Zhang, Peng Gao, Yongping Zhu, Xiao Chen, Qiuyan Guo, Junzhe Zhang, Nan Ma, Jigang Wang
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-18 (2021)
Abstract Background Celastrol (cel) was one of the earliest isolated and identified chemical constituents of Tripterygium wilfordii Hook. f. Based on a cel probe (cel-p) that maintained the bioactivity of the parent compound, the targets of cel in ce
Externí odkaz:
https://doaj.org/article/b532d96e759d4decab0bf7b48a44b9cf