Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Livnat Jerby-Arnon"'
Autor:
Amy Li, Rebecca H. Herbst, David Canner, Jason M. Schenkel, Olivia C. Smith, Jonathan Y. Kim, Michelle Hillman, Arjun Bhutkar, Michael S. Cuoco, C. Garrett Rappazzo, Patricia Rogers, Celeste Dang, Livnat Jerby-Arnon, Orit Rozenblatt-Rosen, Le Cong, Michael Birnbaum, Aviv Regev, Tyler Jacks
Publikováno v:
Cell Reports, Vol 29, Iss 10, Pp 2998-3008.e8 (2019)
Summary: Regulatory T cells (Tregs) can impair anti-tumor immune responses and are associated with poor prognosis in multiple cancer types. Tregs in human tumors span diverse transcriptional states distinct from those of peripheral Tregs, but their c
Externí odkaz:
https://doaj.org/article/23e127cdd30c49738de5fb370ca4ae6d
Autor:
Joo Sang Lee, Avinash Das, Livnat Jerby-Arnon, Rand Arafeh, Noam Auslander, Matthew Davidson, Lynn McGarry, Daniel James, Arnaud Amzallag, Seung Gu Park, Kuoyuan Cheng, Welles Robinson, Dikla Atias, Chani Stossel, Ella Buzhor, Gidi Stein, Joshua J. Waterfall, Paul S. Meltzer, Talia Golan, Sridhar Hannenhalli, Eyal Gottlieb, Cyril H. Benes, Yardena Samuels, Emma Shanks, Eytan Ruppin
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Synthetic lethality (SL) offers a new precision oncology approach, which is based on targeting cancer-specific vulnerabilities across the whole genome, going beyond cancer drivers. The authors develop an approach termed ISLE to identify clinically re
Externí odkaz:
https://doaj.org/article/3a4240165a2541088f4b9ac5ea8738dc
Autor:
Livnat Jerby-Arnon, Aviv Regev
Publikováno v:
Nature Biotechnology. 40:1467-1477
Deciphering the functional interactions of cells in tissues remains a major challenge. Here we describe DIALOGUE, a method to systematically uncover multicellular programs (MCPs)-combinations of coordinated cellular programs in different cell types t
Autor:
Tamar Geiger, Eytan Ruppin, Neta Erez, Livnat Jerby-Arnon, Michael Selitrennik, Lir Beck, Michal Harel, Tamar Shami, Joo Sang Lee, Georgina D. Barnabas
Supplementary Figure S2. Cell proliferation and glycolytic activity upon transient IDH2 overexpression A-B - Quantification of the integrated density of cellROX staining in control and IDH2-overexpressing cells (A) and in the control and IDH2 knockou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e614cea98e2d091e46bf06bf7751f2c2
https://doi.org/10.1158/0008-5472.22426005.v1
https://doi.org/10.1158/0008-5472.22426005.v1
Autor:
Tamar Geiger, Eytan Ruppin, Neta Erez, Livnat Jerby-Arnon, Michael Selitrennik, Lir Beck, Michal Harel, Tamar Shami, Joo Sang Lee, Georgina D. Barnabas
Supplementary Table S3: Eigenprotein modules and the metabolic pathway enrichments
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3052a7943f54fdc88e0272f7b9e5b371
https://doi.org/10.1158/0008-5472.22425975
https://doi.org/10.1158/0008-5472.22425975
Autor:
Tamar Geiger, Eytan Ruppin, Neta Erez, Livnat Jerby-Arnon, Michael Selitrennik, Lir Beck, Michal Harel, Tamar Shami, Joo Sang Lee, Georgina D. Barnabas
Cancer-specific metabolic phenotypes and their vulnerabilities represent a viable area of cancer research. In this study, we explored the association of breast cancer subtypes with different metabolic phenotypes and identified isocitrate dehydrogenas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d3b537d670ff5abd8b28e02506301ef
https://doi.org/10.1158/0008-5472.c.6512196
https://doi.org/10.1158/0008-5472.c.6512196
Autor:
Yanay Rosen, Timothy L. Tickle, Joshua Gould, Satyen H. Gohil, Danielle Dionne, Natalie B. Collins, Gabriela Smith-Rosario, Orr Ashenberg, Michal Slyper, Johanna Klughammer, Avinash Waghray, Julia Waldman, F. Stephen Hodi, Anand G. Patel, Catherine J. Wu, Sébastien Vigneau, Simon Gritsch, Masashi Nomura, Eugene Drokhlyansky, Suzanne J. Baker, Sara Napolitano, Isaac Wakiro, Mario L. Suvà, Caroline B. M. Porter, Aviv Regev, Nikhil Wagle, Jingyi Wu, Ursula A. Matulonis, Elizabeth H. Stover, Michael A. Dyer, Orit Rozenblatt-Rosen, Charles H. Yoon, Aaron N. Hata, Asa Karlstrom, Bruce E. Johnson, Rizwan Haq, Bo Li, Christopher Smillie, Matan Hofree, Michael R. Clay, Lan Nguyen, Raphael Bueno, Judit Jané-Valbuena, Alexander M. Tsankov, Benjamin Izar, Peter J. Tramontozzi, Ofir Cohen, Livnat Jerby-Arnon, Mei-Ju Su, Asaf Rotem
Publikováno v:
Nature Medicine
Single-cell genomics is essential to chart tumor ecosystems. Although single-cell RNA-Seq (scRNA-Seq) profiles RNA from cells dissociated from fresh tumors, single-nucleus RNA-Seq (snRNA-Seq) is needed to profile frozen or hard-to-dissociate tumors.
Autor:
Jonathan Y. Kim, Michael E. Birnbaum, Patricia Rogers, Olivia Smith, Tyler Jacks, Celeste Dang, Arjun Bhutkar, Aviv Regev, Jason M. Schenkel, Michelle Hillman, Amy Li, David Canner, Livnat Jerby-Arnon, Le Cong, Orit Rozenblatt-Rosen, Rebecca H. Herbst, C. Garrett Rappazzo, Michael S. Cuoco
Publikováno v:
Cell Reports, Vol 29, Iss 10, Pp 2998-3008.e8 (2019)
Summary: Regulatory T cells (Tregs) can impair anti-tumor immune responses and are associated with poor prognosis in multiple cancer types. Tregs in human tumors span diverse transcriptional states distinct from those of peripheral Tregs, but their c
Autor:
Oana Ursu, James T. Neal, Emily Shea, Pratiksha I. Thakore, Livnat Jerby-Arnon, Lan Nguyen, Danielle Dionne, Celeste Diaz, Julia Bauman, Mariam Mounir Mosaad, Christian Fagre, April Lo, Maria McSharry, Andrew O. Giacomelli, Seav Huong Ly, Orit Rozenblatt-Rosen, William C. Hahn, Andrew J. Aguirre, Alice H. Berger, Aviv Regev, Jesse S. Boehm
Publikováno v:
Nature Biotechnology. 40:1691-1691
Autor:
Tamar Geiger, Georgina D. Barnabas, Eytan Ruppin, Livnat Jerby-Arnon, Joo Sang Lee, Tamar Shami, Neta Erez, Michal Harel, Lir Beck, Michael Selitrennik
Publikováno v:
Cancer Res
Cancer Research
Cancer Research
Cancer-specific metabolic phenotypes and their vulnerabilities represent a viable area of cancer research. In this study, we explored the association of breast cancer subtypes with different metabolic phenotypes and identified isocitrate dehydrogenas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f023b87e6c52f93218cbfb51beea526
https://europepmc.org/articles/PMC9216326/
https://europepmc.org/articles/PMC9216326/