Zobrazeno 1 - 10
of 185
pro vyhledávání: '"Livio Luongo"'
Autor:
Francesca Guida, Monica Iannotta, Anna Lauritano, Rosmara Infantino, Emanuela Salviati, Roberta Verde, Livio Luongo, Eduardo Maria Sommella, Fabio Arturo Iannotti, Pietro Campiglia, Sabatino Maione, Vincenzo Di Marzo, Fabiana Piscitelli
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-23 (2024)
Abstract Background Despite extensive studies on the neurobiological correlates of traumatic brain injury (TBI), little is known about its molecular determinants on long-term consequences, such as dementia and Alzheimer’s disease (AD). Methods Here
Externí odkaz:
https://doaj.org/article/da93149fc88b4680949790744c03cb48
Autor:
Alfonso Papa, Anna Maria Salzano, Maria Teresa Di Dato, Vincenzo Desiderio, Pietro Buonavolontà, Pietro Mango, Elisabetta Saracco, Dario Tammaro, Livio Luongo, Sabatino Maione
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/0538fe1a85b342389ad3347fe5f46a9b
Autor:
Serena Notartomaso, Nico Antenucci, Mariacristina Mazzitelli, Xavier Rovira, Serena Boccella, Flavia Ricciardi, Francesca Liberatore, Xavier Gomez-Santacana, Tiziana Imbriglio, Milena Cannella, Charleine Zussy, Livio Luongo, Sabatino Maione, Cyril Goudet, Giuseppe Battaglia, Amadeu Llebaria, Ferdinando Nicoletti, Volker Neugebauer
Publikováno v:
eLife, Vol 13 (2024)
We used light-sensitive drugs to identify the brain region-specific role of mGlu5 metabotropic glutamate receptors in the control of pain. Optical activation of systemic JF-NP-26, a caged, normally inactive, negative allosteric modulator (NAM) of mGl
Externí odkaz:
https://doaj.org/article/7992b22d74894ac98d325b25e79626e5
Autor:
Alfonso Papa, Anna Maria Salzano, Maria Teresa Di Dato, Vincenzo Desiderio, Pietro Buonavolontà, Pietro Mango, Elisabetta Saracco, Dario Tammaro, Livio Luongo, Sabatino Maione
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
BackgroundChronic pain significantly impacts quality of life and poses substantial public health challenges. Buprenorphine, a synthetic analog of thebaine, is recognized for its potential in managing moderate to severe chronic pain with fewer side ef
Externí odkaz:
https://doaj.org/article/39181e76d3b64306974fad91e3d36e1a
Autor:
Fabiana Russo, Maria Angela Vandelli, Giuseppe Biagini, Martin Schmid, Livio Luongo, Michela Perrone, Federica Ricciardi, Sabatino Maione, Aldo Laganà, Anna Laura Capriotti, Alfonso Gallo, Luigi Carbone, Elisabetta Perrone, Giuseppe Gigli, Giuseppe Cannazza, Cinzia Citti
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Cannabis is a multifaceted plant with numerous therapeutic properties on one hand, and controversial psychotropic activities on the other hand, which are modulated by CB1 endocannabinoid receptors. Δ9-Tetrahydrocannabinol (Δ9-THC) has been
Externí odkaz:
https://doaj.org/article/ad469d71ebe8463ab8901867dfc99cb5
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S635- (2023)
Externí odkaz:
https://doaj.org/article/3efe70c7277e457f8714f8b57e33e7b3
Autor:
Serena Boccella, Lidia De Filippis, Cristina Giorgio, Laura Brandolini, Meghan Jones, Rubina Novelli, Ezio Amorizzo, Matteo Luigi Giuseppe Leoni, Gaetano Terranova, Sabatino Maione, Livio Luongo, Manuela Leone, Marcello Allegretti, Enrico Maria Minnella, Andrea Aramini
Publikováno v:
Biomolecules, Vol 13, Iss 12, p 1802 (2023)
Chronic neuropathic pain (NP) is an increasingly prevalent disease and leading cause of disability which is challenging to treat. Several distinct classes of drugs are currently used for the treatment of chronic NP, but each drug targets only narrow
Externí odkaz:
https://doaj.org/article/8bbf5bb8bb154cb0b526fbf73da40a77
Autor:
Serena Boccella, Francesca Guida, Monica Iannotta, Fabio Arturo Iannotti, Rosmara Infantino, Flavia Ricciardi, Claudia Cristiano, Rosa Maria Vitale, Pietro Amodeo, Ida Marabese, Carmela Belardo, Vito de Novellis, Salvatore Paino, Enza Palazzo, Antonio Calignano, Vincenzo Di Marzo, Sabatino Maione, Livio Luongo
Publikováno v:
Molecular Brain, Vol 14, Iss 1, Pp 1-24 (2021)
Abstract Neuropathic pain (NP) remains an untreatable disease due to the complex pathophysiology that involves the whole pain neuraxis including the forebrain. Sensory dysfunctions such as allodynia and hyperalgesia are only part of the symptoms asso
Externí odkaz:
https://doaj.org/article/70f2925773ac4daa8f816652716a2dda
Autor:
Serena Notartomaso, Serena Boccella, N. Antenucci, Flavia Ricciardi, Francesco Fazio, F. Liberatore, P. Scarselli, M. Scioli, Giada Mascio, V. Bruno, Giuseppe Battaglia, Ferdinando Nicoletti, Sabatino Maione, Livio Luongo
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Cinnabarinic acid (CA) is a trace kynurenine metabolite, which activates both type-4 metabotropic glutamate (mGlu4) and arylic hydrocarbon (Ah) receptors. We examined the action of CA in models of inflammatory and neuropathic pain moving from the evi
Externí odkaz:
https://doaj.org/article/d2a42c5aabdb496ca06d4339c75ed2a4
Autor:
Pasquale Linciano, Cinzia Citti, Fabiana Russo, Francesco Tolomeo, Aldo Laganà, Anna Laura Capriotti, Livio Luongo, Monica Iannotta, Carmela Belardo, Sabatino Maione, Flavio Forni, Maria Angela Vandelli, Giuseppe Gigli, Giuseppe Cannazza
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Abstract The two most important and studied phytocannabinoids present in Cannabis sativa L. are undoubtedly cannabidiol (CBD), a non-psychotropic compound, but with other pharmacological properties, and Δ9-tetrahydrocannabinol (Δ9-THC), which inste
Externí odkaz:
https://doaj.org/article/e2be800a38e640f98a7de8fd6927174c