Výsledky vyhledávání - "Livia Yamashiro"

801 The anti-tumor efficacy of immunogenic chemotherapy is enhanced by the dual A2aR/A2bR antagonist etrumadenant, relieving the necessity for an extended chemotherapy regimen

Autor: Daniel DiRenzo, Dana Piovesan, Ferdie Soriano, Livia Yamashiro, Janine Kline, Dillon Miles, Ehesan Sharif, Manmohan Leleti, Matthew Walters

Publikováno v: Regular and Young Investigator Award Abstracts.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e59743abddcc71fbe50f4b4683b030c7
https://doi.org/10.1136/jitc-2022-sitc2022.0801

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Abstract 256: Dual A2aR/A2bR antagonism with etrumadenant (AB928) eliminates the suppressive effects of adenosine on immune and cancer cells in the tumor microenvironment

Autor: Sachie Marubayashi, Bindi Patel, Livia Yamashiro, Dana Piovesan, Sean Cho, Jenna Jeffrey, Manmohan Leleti, Jay Powers, Matt Walters, Daniel DiRenzo

Publikováno v: Cancer Research. 82:256-256

INTRODUCTION: Tumors employ many strategies to attenuate immune responses. High levels of extracellular adenosine generated in the tumor microenvironment engage A2a and A2b adenosine receptors on immune cells, resulting in immunosuppression. Expressi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7291fa784613aa5130388c779dedc78a
https://doi.org/10.1158/1538-7445.am2022-256

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